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European Journal of Clinical Pharmacology, ISSN 0031-6970, 3/2013, Volume 69, Issue 3, pp. 377 - 383
Gamma-glutamyl hydrolase (GGH), cyclin D1 (CCND1) and thymidylate synthase (TS) genes encode enzymes that are involved in methotrexate (MTX) action. In a group... 
Biomedicine | Pharmacology/Toxicology | Methotrexate | Rheumatoid arthritis | Genetic polymorphism | MODIFYING ANTIRHEUMATIC DRUGS | REDUCED FOLATE CARRIER | G870A POLYMORPHISM | COMMON POLYMORPHISMS | RHEUMATOID-ARTHRITIS PATIENTS | ACUTE LYMPHOBLASTIC-LEUKEMIA | CANCER SUSCEPTIBILITY | FUNCTIONAL-ANALYSIS | PHARMACOLOGY & PHARMACY | REDUCTASE GENES | THYMIDYLATE-SYNTHASE | Bone Marrow Diseases - enzymology | Multivariate Analysis | Humans | Methotrexate - pharmacokinetics | Middle Aged | gamma-Glutamyl Hydrolase - metabolism | Male | Young Adult | Arthritis, Rheumatoid - drug therapy | Aged, 80 and over | Antirheumatic Agents - adverse effects | Adult | Female | Odds Ratio | gamma-Glutamyl Hydrolase - genetics | Arthritis, Rheumatoid - diagnosis | Bone Marrow - drug effects | Severity of Illness Index | Genetic Predisposition to Disease | Pharmacogenetics | Bone Marrow Diseases - chemically induced | Gene Frequency | Risk Factors | Thymidylate Synthase - metabolism | Arthritis, Rheumatoid - enzymology | Logistic Models | Chi-Square Distribution | Thymidylate Synthase - genetics | Bone Marrow Diseases - genetics | Polymorphism, Genetic | Methotrexate - adverse effects | Arthritis, Rheumatoid - genetics | Phenotype | Analysis of Variance | Cyclin D1 - genetics | Antirheumatic Agents - pharmacokinetics | Aged | Rheumatoid factor | Complications and side effects | Enzymes | Genes | Hydrolases | Genetic aspects | Universities and colleges | Bone marrow | Genotype & phenotype | Drug therapy | Toxicity | Patients | Index Medicus
Journal Article
Journal Article
Journal Article
Genetika, ISSN 0534-0012, 2014, Volume 46, Issue 2, pp. 621 - 629
Physicians usually do not suspect pulmonary thromboembolism in younger patients except in those who have thrombophilia. In those latter patients some special... 
Thrombophilia | Genetic | Pulmonary thromboembolism | Risk factors | genetic | risk factors | AGRONOMY | RISK-FACTORS | THYROID-DYSFUNCTION | DEEP-VEIN THROMBOSIS | pulmonary thromboembolism | FAMILY-HISTORY | thrombophilia | 1ST | VENOUS THROMBOEMBOLISM | PULMONARY-EMBOLISM | GENETICS & HEREDITY | COAGULATION | PATIENT
Journal Article
Genetika, ISSN 0534-0012, 2016, Volume 48, Issue 2, pp. 707 - 716
Retinopathy of prematurity (ROP) is a vascular proliferative disorder of retina, that causes visual impairment in premature children. Beside well known risk... 
4a/b polymorphism | Retinopathy of prematurity | SNP | T-786C polymorphism | ENOS gene | AGRONOMY | RISK-FACTORS | VARIANTS | eNOS gene | GENETICS & HEREDITY | GROWTH-FACTOR | ASSOCIATION | retinopathy of prematurity
Journal Article
Acta chirurgica Iugoslavica, ISSN 0354-950X, 2016, Volume 63, Issue 2, pp. 35 - 40
Journal Article
American Journal of Human Genetics, ISSN 0002-9297, 09/2010, Volume 87, Issue 3, pp. 376 - 381
Retinitis pigmentosa (RP) is a degenerative disease of the retina leading to progressive loss of vision and, in many instances, to legal blindness at the end... 
Journal Article
Expert Opinion on Drug Metabolism & Toxicology, ISSN 1742-5255, 03/2019, Volume 15, Issue 3, pp. 253 - 257
Background: Methotrexate (MTX), a folate analogue, is the most commonly used disease-modifying drug in the treatment of rheumatoid arthritis (RA). However,... 
DHFR | toxicity | methotrexate | genetic polymorphism | rheumatoid arthritis | pharmacogenetics | EFFICACY | GENOTYPE | BIOCHEMISTRY & MOLECULAR BIOLOGY | POOR RESPONSE | DISEASE | RESISTANCE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Index Medicus
Journal Article
Archives of Biological Sciences, ISSN 0354-4664, 2014, Volume 66, Issue 2, pp. 729 - 734
The effect of 5,10-methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism on serum lipid profiles is controversial. We randomly selected 530... 
Schoolchildren | MTHFR gene | MTHFR 677T allele | Lipid levels | Atherosclerosis | Polymorphism | atherosclerosis | schoolchildren | lipid levels | polymorphism
Journal Article
Journal of Medical Biochemistry, ISSN 1452-8258, 01/2014, Volume 33, Issue 1, pp. 3 - 7
Molecular genetic testing is part of modern medical practice. DNA tests are an essential part of diagnostics and genetic counseling in single gene diseases,... 
molecular genetics | metode | genetic counselling | test | methods | testovi | genetičko savetovanje | molekularna genetika
Journal Article
Genetika, ISSN 0534-0012, 2013, Volume 45, Issue 3, pp. 865 - 872
Apolipoprotein E (ApoE) play important role in lipid metabolism and in processes of remodeling and reparation in central nervous system. Three common ApoE... 
Population study | Serbia | Apolipoprotein E | ε 4allele | Gene polymorphism | AGRONOMY | RISK-FACTORS | DEMENTIA | GENOTYPE | ALZHEIMERS-DISEASE | MARKERS | gene polymorphism | COGNITIVE IMPAIRMENT | FOLLOW-UP | PATTERNS | epsilon 4 allele | population study | GENETICS & HEREDITY | apolipoprotein E | APOE | ε4 allele
Journal Article
JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, ISSN 1482-1826, 04/2019, Volume 22, Issue 1, pp. 142 - 149
Purpose: Treatment of Ischemic stroke (IS) in acute phase is based on the use of thrombolytic rt-PA therapy. We aimed to determine whether different alleles... 
SYSTEMATIC ANALYSIS | GLOBAL BURDEN | HEART | RISK-FACTORS | PLASMINOGEN-ACTIVATOR | GENOTYPE | CARDIOVASCULAR-DISEASE | PHARMACOLOGY & PHARMACY | 4G/5G POLYMORPHISM | ANGIOTENSIN-CONVERTING ENZYME | HEALTH-CARE PROFESSIONALS
Journal Article
Genetika, ISSN 0534-0012, 2016, Volume 48, Issue 1, pp. 395 - 408
A folate analogue methotrexate (MTX) is the most commonly used disease-modifying drug in the treatment of rheumatoid arthritis. However, the clinical response... 
MTHFR | MTHFD1 | RFC1 | Methotrexate | Rheumatoid arthritis | Genetic polymorphism | methotrexate | genetic polymorphism | rheumatoid arthritis
Journal Article
Journal of Medical Biochemistry, ISSN 1452-8258, 2014, Volume 33, Issue 1, pp. 3 - 7
Journal Article
Archives of Biological Sciences, ISSN 0354-4664, 2014, Volume 66, Issue 3, pp. 1055 - 1059
Myelodysplastic syndromes (MDS) are clonal hematologic stem cell disorders with an as yet unknown molecular pathology. Genetic instability has been proposed as... 
657DEL5 | MDS | NBS1 mutations | Nibrin | CELLS | COMPLEX | PROTEIN | NIJMEGEN BREAKAGE SYNDROME | DNA-DAMAGE RESPONSE | REPAIR | TELOMERE DYSFUNCTION | 657del5 | BIOLOGY | nibrin | ATAXIA-TELANGIECTASIA | APLASTIC-ANEMIA | ASSOCIATION
Journal Article
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