Arthritis & rheumatology (Hoboken, N.J.), ISSN 2326-5191, 02/2016, Volume 68, Issue 2, pp. 282 - 298
To provide evidence-based recommendations for the treatment of patients with ankylosing spondylitis (AS) and nonradiographic axial spondyloarthritis (SpA). A...
Spondylarthropathies - complications | Glucocorticoids - therapeutic use | Spondylarthropathies - diagnostic imaging | Spondylarthritis - diagnostic imaging | United States | Humans | Spondylitis, Ankylosing - therapy | Spondylitis, Ankylosing - complications | Infliximab - therapeutic use | Rheumatology - standards | Societies, Medical | Physical Therapy Modalities | Inflammatory Bowel Diseases - complications | Antirheumatic Agents - therapeutic use | Arthroplasty, Replacement, Hip | Spondylarthritis - therapy | Evidence-Based Medicine | Spondylarthropathies - therapy | Spondylitis, Ankylosing - diagnostic imaging | Radiography | Adalimumab - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Spondylarthritis - complications | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Etanercept - therapeutic use
Spondylarthropathies - complications | Glucocorticoids - therapeutic use | Spondylarthropathies - diagnostic imaging | Spondylarthritis - diagnostic imaging | United States | Humans | Spondylitis, Ankylosing - therapy | Spondylitis, Ankylosing - complications | Infliximab - therapeutic use | Rheumatology - standards | Societies, Medical | Physical Therapy Modalities | Inflammatory Bowel Diseases - complications | Antirheumatic Agents - therapeutic use | Arthroplasty, Replacement, Hip | Spondylarthritis - therapy | Evidence-Based Medicine | Spondylarthropathies - therapy | Spondylitis, Ankylosing - diagnostic imaging | Radiography | Adalimumab - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Spondylarthritis - complications | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Etanercept - therapeutic use
Journal Article
The Journal of rheumatology, ISSN 0315-162X, 05/2019, Volume 46, Issue 5, pp. 542 - 542
Journal Article
NATURE REVIEWS RHEUMATOLOGY, ISSN 1759-4790, 11/2019, Volume 15, Issue 11, pp. 657 - 672
MRI of the sacroiliac joints is increasingly acknowledged as being indispensable in the early diagnosis of axial spondyloarthritis (axSpA) and as having a...
POSITRON-EMISSION-TOMOGRAPHY | RESEARCH CONSORTIUM | BONE-FORMATION | LOW-DOSE CT | RADIOGRAPHIC SACROILIITIS PROGRESSION | FOLLOW-UP | STRUCTURAL LESIONS | ANKYLOSING-SPONDYLITIS | RHEUMATOLOGY | INFLAMMATORY BACK-PAIN | CLASSIFICATION CRITERIA
POSITRON-EMISSION-TOMOGRAPHY | RESEARCH CONSORTIUM | BONE-FORMATION | LOW-DOSE CT | RADIOGRAPHIC SACROILIITIS PROGRESSION | FOLLOW-UP | STRUCTURAL LESIONS | ANKYLOSING-SPONDYLITIS | RHEUMATOLOGY | INFLAMMATORY BACK-PAIN | CLASSIFICATION CRITERIA
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 4340 - 13
Non-genetic MMP-2 insufficiency is a relatively unexplored condition which could be induced by pathological overexpression of endogenous MMP-2 inhibitors such...
CLUSPRO | MATRIX METALLOPROTEINASES | GELATINASE-A | MECHANISM | MULTIDISCIPLINARY SCIENCES | MUTATION | EXTRACELLULAR-MATRIX | MULTICENTRIC OSTEOLYSIS | ALPHA-2-MACROGLOBULIN | PLATELET ACTIVATION | WEB SERVER | a2-Macroglobulin | Gelatin | Fluorescein | Fibrinogen | Arthritis | Gelatinase B | Gelatinase A
CLUSPRO | MATRIX METALLOPROTEINASES | GELATINASE-A | MECHANISM | MULTIDISCIPLINARY SCIENCES | MUTATION | EXTRACELLULAR-MATRIX | MULTICENTRIC OSTEOLYSIS | ALPHA-2-MACROGLOBULIN | PLATELET ACTIVATION | WEB SERVER | a2-Macroglobulin | Gelatin | Fluorescein | Fibrinogen | Arthritis | Gelatinase B | Gelatinase A
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2019, Volume 10, p. 305
There exists a major unmet need for biomarkers that can identify axial spondyloarthritis (axSpA) early after disease onset because of the availability of...
ankylosing spondylitis | diagnosis | multiomics | biomarker | axial spondyloarthritis | imaging | prognosis | AUTOANTIBODIES | POTENTIAL BIOMARKERS | MARKERS | ANKYLOSING-SPONDYLITIS | IMMUNOLOGY | BLOOD MONONUCLEAR-CELLS | FECAL CALPROTECTIN | RADIOGRAPHIC SPINAL PROGRESSION | INFLAMMATION | STRUCTURAL DAMAGE | EXPRESSION
ankylosing spondylitis | diagnosis | multiomics | biomarker | axial spondyloarthritis | imaging | prognosis | AUTOANTIBODIES | POTENTIAL BIOMARKERS | MARKERS | ANKYLOSING-SPONDYLITIS | IMMUNOLOGY | BLOOD MONONUCLEAR-CELLS | FECAL CALPROTECTIN | RADIOGRAPHIC SPINAL PROGRESSION | INFLAMMATION | STRUCTURAL DAMAGE | EXPRESSION
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 07/2018, Volume 20, Issue 1, pp. 141 - 9
Background: We aimed to evaluate the diagnostic utility of pelvic radiographs versus magnetic resonance imaging (MRI) of the sacroiliac joints in children with...
Juvenile spondyloarthritis | Radiograph | Misclassification | Magnetic resonance imaging | Sacroiliitis | DIAGNOSIS | ASSESSMENTS | RESONANCE-IMAGING MRI | RHEUMATOLOGY | Medical examination | Sacroiliac joint | Diagnosis, Radioscopic | Patient outcomes | Pediatric radiology | Consortia | Studies | Radiography | Edema | Nuclear magnetic resonance--NMR | Inflammation | Arthritis | Bone density
Juvenile spondyloarthritis | Radiograph | Misclassification | Magnetic resonance imaging | Sacroiliitis | DIAGNOSIS | ASSESSMENTS | RESONANCE-IMAGING MRI | RHEUMATOLOGY | Medical examination | Sacroiliac joint | Diagnosis, Radioscopic | Patient outcomes | Pediatric radiology | Consortia | Studies | Radiography | Edema | Nuclear magnetic resonance--NMR | Inflammation | Arthritis | Bone density
Journal Article
Drugs, ISSN 0012-6667, 09/2018, Volume 78, Issue 14, pp. 1397 - 1418
Axial spondyloarthritis (axSpA) is a complex disease that affects the joints and entheses of axial and peripheral joints, and is associated with inflammation...
PHASE-III TRIAL | INFLAMMATORY-BOWEL-DISEASE | IMMUNE-MEDIATED DISEASES | PHARMACOLOGY & PHARMACY | NECROSIS-FACTOR-ALPHA | TOXICOLOGY | PLACEBO-CONTROLLED TRIAL | INNATE LYMPHOID-CELLS | ACTIVE ANKYLOSING-SPONDYLITIS | SOCIETY CLASSIFICATION CRITERIA | GENOME-WIDE ASSOCIATION | PROOF-OF-CONCEPT | Spondylarthritis - etiology | Unfolded Protein Response - genetics | Spondylarthritis - immunology | Humans | Spondylitis, Ankylosing - drug therapy | Spondylarthritis - drug therapy | HLA-B27 Antigen - metabolism | Spondylitis, Ankylosing - immunology | Interleukin-17 - metabolism | Inflammation - metabolism | Animals | Endoplasmic Reticulum Stress | Spondylitis, Ankylosing - etiology | Molecular Targeted Therapy - methods | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Biological Products - therapeutic use | Back pain | Nuclear magnetic resonance--NMR | Pathogenesis | Mucosa | Interleukin | Medical services | Phosphodiesterase IV | Interleukin 22 | Stimulation | Interleukin 23 | Lymphocytes T | Arthritis | Kinases | Cell surface | Inflammatory diseases | Interleukin 6 | Proteins | Interleukin 7 | Receptors | Immunology | Lymphocytes | Janus kinase | Tumor necrosis factor-TNF | Genetics | Natural killer cells | Ankylosing spondylitis | Physical therapy | Genotypes | Phosphodiesterase | Immune system | Myeloid cells | Psoriasis | Cytokines | Inflammation | FDA approval | Gene expression | Joint diseases | Patients | Interleukin 17 | Inflammatory bowel disease | Inhibitors | Interferon | Histocompatibility antigen HLA | Aminopeptidase | Endoplasmic reticulum | Phagocytosis
PHASE-III TRIAL | INFLAMMATORY-BOWEL-DISEASE | IMMUNE-MEDIATED DISEASES | PHARMACOLOGY & PHARMACY | NECROSIS-FACTOR-ALPHA | TOXICOLOGY | PLACEBO-CONTROLLED TRIAL | INNATE LYMPHOID-CELLS | ACTIVE ANKYLOSING-SPONDYLITIS | SOCIETY CLASSIFICATION CRITERIA | GENOME-WIDE ASSOCIATION | PROOF-OF-CONCEPT | Spondylarthritis - etiology | Unfolded Protein Response - genetics | Spondylarthritis - immunology | Humans | Spondylitis, Ankylosing - drug therapy | Spondylarthritis - drug therapy | HLA-B27 Antigen - metabolism | Spondylitis, Ankylosing - immunology | Interleukin-17 - metabolism | Inflammation - metabolism | Animals | Endoplasmic Reticulum Stress | Spondylitis, Ankylosing - etiology | Molecular Targeted Therapy - methods | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Biological Products - therapeutic use | Back pain | Nuclear magnetic resonance--NMR | Pathogenesis | Mucosa | Interleukin | Medical services | Phosphodiesterase IV | Interleukin 22 | Stimulation | Interleukin 23 | Lymphocytes T | Arthritis | Kinases | Cell surface | Inflammatory diseases | Interleukin 6 | Proteins | Interleukin 7 | Receptors | Immunology | Lymphocytes | Janus kinase | Tumor necrosis factor-TNF | Genetics | Natural killer cells | Ankylosing spondylitis | Physical therapy | Genotypes | Phosphodiesterase | Immune system | Myeloid cells | Psoriasis | Cytokines | Inflammation | FDA approval | Gene expression | Joint diseases | Patients | Interleukin 17 | Inflammatory bowel disease | Inhibitors | Interferon | Histocompatibility antigen HLA | Aminopeptidase | Endoplasmic reticulum | Phagocytosis
Journal Article
Current Rheumatology Reports, ISSN 1523-3774, 10/2019, Volume 21, Issue 10, pp. 1 - 10
Ankylosing spondyloarthritis (AS) is a chronic inflammatory disease that involves the axial joints and entheses. Extra-spinal manifestations such as anterior...
Immunology | Medicine & Public Health | Pathogenesis | Genes | Rheumatology | HLA-B27 | Ankylosing spondylitis | Microbiome
Immunology | Medicine & Public Health | Pathogenesis | Genes | Rheumatology | HLA-B27 | Ankylosing spondylitis | Microbiome
Journal Article
Nature Reviews Rheumatology, ISSN 1759-4790, 03/2018, Volume 14, Issue 3, pp. 130 - 131
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 03/2018, Volume 20, Issue 1, pp. 56 - 7
Background: Published methods for quantification of magnetic resonance imaging (MRI) evidence of inflammation in the sacroiliac joint lack validation in...
Spondyloarthritis | Imaging | Ankylosing spondylitis | Outcomes | Juvenile idiopathic arthritis | ADALIMUMAB | MRI | JUVENILE-ONSET | DOUBLE-BLIND | RHEUMATOLOGY | ONSET ANKYLOSING-SPONDYLITIS | AXIAL SPONDYLOARTHRITIS | Severity of Illness Index | Reproducibility of Results | Spondylarthritis - diagnostic imaging | Sacroiliitis - epidemiology | Humans | Male | Osteitis - diagnostic imaging | Osteitis - epidemiology | Feasibility Studies | Sacroiliitis - diagnostic imaging | Canada - epidemiology | Adolescent | Female | Child | Biomedical Research - standards | Sacroiliac Joint - diagnostic imaging | Spondylarthritis - epidemiology | Spondyloarthropathies | Evaluation | Medical tests | Diagnosis | Children | Diseases
Spondyloarthritis | Imaging | Ankylosing spondylitis | Outcomes | Juvenile idiopathic arthritis | ADALIMUMAB | MRI | JUVENILE-ONSET | DOUBLE-BLIND | RHEUMATOLOGY | ONSET ANKYLOSING-SPONDYLITIS | AXIAL SPONDYLOARTHRITIS | Severity of Illness Index | Reproducibility of Results | Spondylarthritis - diagnostic imaging | Sacroiliitis - epidemiology | Humans | Male | Osteitis - diagnostic imaging | Osteitis - epidemiology | Feasibility Studies | Sacroiliitis - diagnostic imaging | Canada - epidemiology | Adolescent | Female | Child | Biomedical Research - standards | Sacroiliac Joint - diagnostic imaging | Spondylarthritis - epidemiology | Spondyloarthropathies | Evaluation | Medical tests | Diagnosis | Children | Diseases
Journal Article
CLINICAL RHEUMATOLOGY, ISSN 0770-3198, 06/2016, Volume 35, Issue 6, pp. 1447 - 1455
Plain radiography remains the benchmark for diagnostic evaluation of spondyloarthritis although MRI has much great sensitivity because it can detect a variety...
BASE-LINE | MULTICENTER | ADALIMUMAB | MRI | SACROILIAC JOINTS | ANKYLOSING-SPONDYLITIS | RHEUMATOLOGY | Spondyloarthritis | INFLAMMATORY BACK-PAIN | DOUBLE-BLIND | Short tau inversion recovery (STIR) | DIAGNOSTIC UTILITY | SPINAL INFLAMMATION | AXIAL SPONDYLOARTHRITIS | Back Pain - etiology | Magnetic Resonance Imaging | Sacroiliitis - diagnostic imaging | Sacroiliac Joint - pathology | Spine - diagnostic imaging | Spondylarthritis - diagnostic imaging | Humans | Spine - pathology | Sacroiliac Joint - diagnostic imaging | Magnetic resonance imaging | Backache
BASE-LINE | MULTICENTER | ADALIMUMAB | MRI | SACROILIAC JOINTS | ANKYLOSING-SPONDYLITIS | RHEUMATOLOGY | Spondyloarthritis | INFLAMMATORY BACK-PAIN | DOUBLE-BLIND | Short tau inversion recovery (STIR) | DIAGNOSTIC UTILITY | SPINAL INFLAMMATION | AXIAL SPONDYLOARTHRITIS | Back Pain - etiology | Magnetic Resonance Imaging | Sacroiliitis - diagnostic imaging | Sacroiliac Joint - pathology | Spine - diagnostic imaging | Spondylarthritis - diagnostic imaging | Humans | Spine - pathology | Sacroiliac Joint - diagnostic imaging | Magnetic resonance imaging | Backache
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 11/2019, Volume 78, Issue 11, pp. 1550 - 1558
ObjectivesThe Assessment of SpondyloArthritis international Society (ASAS) MRI working group (WG) was convened to generate a consensus update on standardised...
RADIOGRAPHS | RESEARCH CONSORTIUM | SPINE | INFLAMMATION | DIAGNOSTIC UTILITY | CLASSIFICATION | RHEUMATOLOGY
RADIOGRAPHS | RESEARCH CONSORTIUM | SPINE | INFLAMMATION | DIAGNOSTIC UTILITY | CLASSIFICATION | RHEUMATOLOGY
Journal Article
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, ISSN 0889-857X, 08/2019, Volume 45, Issue 3, pp. 341 - 341
MRI has an important role in the assessment of axial spondyloarthritis (axSpA), particularly early in the disease course, before radiographic damage is...
STRUCTURAL LESIONS | SACROILIAC JOINTS | ANKYLOSING-SPONDYLITIS | RHEUMATOLOGY | Spondyloarthritis | INFLAMMATORY BACK-PAIN | POSITIVE MRI | Radiography | RADIOGRAPHIC PROGRESSION | Magnetic resonance imaging | SPINE | ASAS CRITERIA | DIAGNOSTIC UTILITY | Sacroiliitis | Ankylosing spondylitis | ONSET
STRUCTURAL LESIONS | SACROILIAC JOINTS | ANKYLOSING-SPONDYLITIS | RHEUMATOLOGY | Spondyloarthritis | INFLAMMATORY BACK-PAIN | POSITIVE MRI | Radiography | RADIOGRAPHIC PROGRESSION | Magnetic resonance imaging | SPINE | ASAS CRITERIA | DIAGNOSTIC UTILITY | Sacroiliitis | Ankylosing spondylitis | ONSET
Journal Article
Rheumatic Disease Clinics of North America, ISSN 0889-857X, 11/2016, Volume 42, Issue 4, pp. 645 - 662
The primary use of imaging focuses on diagnostic evaluation, and pelvic radiography is still the primary modality for evaluation of disease in the sacroiliac...
Radiography | Fat metaplasia | Ankylosis | Bone edema | MRI | Erosion | SPONDYLARTHRITIS | SCINTIGRAPHY | SACROILIAC JOINTS | ANKYLOSING-SPONDYLITIS | RHEUMATOLOGY | ACTIVE SACROILIITIS | DIAGNOSTIC UTILITY | CONVENTIONAL RADIOGRAPHY | COHORT | CLINICAL-PRACTICE | Spondylarthropathies - diagnostic imaging | Arthritis - diagnostic imaging | Humans | Tomography, X-Ray Computed | Disease Progression | Spondylarthropathies - classification | Spondylitis, Ankylosing - diagnostic imaging | Edema - diagnostic imaging | Magnetic Resonance Imaging | Saccule and Utricle | Sacroiliac Joint - pathology | Spine - diagnostic imaging | Bone Marrow | Sacroiliac Joint - diagnostic imaging
Radiography | Fat metaplasia | Ankylosis | Bone edema | MRI | Erosion | SPONDYLARTHRITIS | SCINTIGRAPHY | SACROILIAC JOINTS | ANKYLOSING-SPONDYLITIS | RHEUMATOLOGY | ACTIVE SACROILIITIS | DIAGNOSTIC UTILITY | CONVENTIONAL RADIOGRAPHY | COHORT | CLINICAL-PRACTICE | Spondylarthropathies - diagnostic imaging | Arthritis - diagnostic imaging | Humans | Tomography, X-Ray Computed | Disease Progression | Spondylarthropathies - classification | Spondylitis, Ankylosing - diagnostic imaging | Edema - diagnostic imaging | Magnetic Resonance Imaging | Saccule and Utricle | Sacroiliac Joint - pathology | Spine - diagnostic imaging | Bone Marrow | Sacroiliac Joint - diagnostic imaging
Journal Article
Journal of Rheumatology, ISSN 0315-162X, 06/2018, Volume 45, Issue 6, pp. 729 - 730
Journal Article
JOURNAL OF RHEUMATOLOGY, ISSN 0315-162X, 09/2019, Volume 46, Issue 9, pp. 1232 - 1238
Objective. To develop and validate an enthesitis magnetic resonance imaging (MRI) scoring system for spondyloarthritis/psoriatic arthritis, using the heel as...
CRITERIA | SPONDYLOARTHRITIS | MAGNETIC RESONANCE IMAGING | ENTHESOPATHY | OMERACT | RHEUMATOLOGY | PSORIATIC-ARTHRITIS | PSORIATIC ARTHRITIS | SPONDYLOARTHROPATHY
CRITERIA | SPONDYLOARTHRITIS | MAGNETIC RESONANCE IMAGING | ENTHESOPATHY | OMERACT | RHEUMATOLOGY | PSORIATIC-ARTHRITIS | PSORIATIC ARTHRITIS | SPONDYLOARTHROPATHY
Journal Article
Clinical Rheumatology, ISSN 0770-3198, 6/2016, Volume 35, Issue 6, pp. 1447 - 1455
Plain radiography remains the benchmark for diagnostic evaluation of spondyloarthritis although MRI has much great sensitivity because it can detect a variety...
Short tau inversion recovery (STIR) | Medicine & Public Health | MRI | Spondyloarthritis | Rheumatology
Short tau inversion recovery (STIR) | Medicine & Public Health | MRI | Spondyloarthritis | Rheumatology
Journal Article
Journal of rheumatology, ISSN 0315-162X, 2019, Volume 46, Issue 9, pp. 1192 - 1197
Objective. To develop definitions for the assessment of magnetic resonance imaging (MRI) pathologies of the sacroiliac joints (SIJ) in juvenile idiopathic...
SACROILIITIS | DIAGNOSIS | MAGNETIC RESONANCE IMAGING | OMERACT | MANAGEMENT | OUTCOME ASSESSMENT | SPONDYLOARTHRITIS RESEARCH CONSORTIUM | JUVENILE IDIOPATHIC ARTHRITIS | RHEUMATOLOGY
SACROILIITIS | DIAGNOSIS | MAGNETIC RESONANCE IMAGING | OMERACT | MANAGEMENT | OUTCOME ASSESSMENT | SPONDYLOARTHRITIS RESEARCH CONSORTIUM | JUVENILE IDIOPATHIC ARTHRITIS | RHEUMATOLOGY
Journal Article
JOURNAL OF RHEUMATOLOGY, ISSN 0315-162X, 09/2019, Volume 46, Issue 9, pp. 1215 - 1221
Objective. To develop a whole-body magnetic resonance imaging (MRI) scoring system for peripheral arthritis and enthesitis. Methods. After consensus on...
DEFINITIONS | MAGNETIC RESONANCE IMAGING | OMERACT | 1ST STEPS | OUTCOME ASSESSMENT | RHEUMATOLOGY | ARTHRITIS | PSORIATIC-ARTHRITIS | AXIAL SPONDYLOARTHRITIS | DAMAGE
DEFINITIONS | MAGNETIC RESONANCE IMAGING | OMERACT | 1ST STEPS | OUTCOME ASSESSMENT | RHEUMATOLOGY | ARTHRITIS | PSORIATIC-ARTHRITIS | AXIAL SPONDYLOARTHRITIS | DAMAGE
Journal Article