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Cell Reports, ISSN 2211-1247, 06/2019, Volume 27, Issue 10, pp. 3049 - 3061.e6
Adaptor protein 2 (AP2) is a major constituent of clathrin-coated pits (CCPs). Whether it is essential for all forms of clathrin-mediated endocytosis (CME) in... 
AP2 | signaling | transcription | clathrin-coated pits | receptor degradation | endocytosis | recycling | EGFR | epsin | eps15 | endocytic adaptors | Life Sciences
Journal Article
Progress in molecular and subcellular biology, ISSN 0079-6484, 01/2018, Volume 57, pp. 235 - 272
Signaling from the epidermal growth factor receptor (EGFR) elicits multiple biological responses, including cell proliferation, migration, and survival.... 
Journal Article
Science, ISSN 0036-8075, 05/2017, Volume 356, Issue 6338, pp. 617 - 624
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 02/2018, Volume 217, Issue 2, p. 745
Numb functions as an oncosuppressor by inhibiting Notch signaling and stabilizing p53. This latter effect depends on the interaction of Numb with Mdm2, the E3... 
Alternative splicing | MDM2 protein | Splicing | Toxicity | p53 Protein | Genotoxicity | Chemoresistance | Homeostasis | Breast cancer | Fuzzy logic | Degradation | Signaling | Stem cells | Isoforms | NUMB protein | Notch protein | Ubiquitin-protein ligase | Tumors | Cancer
Journal Article
Journal Article
Science (New York, N.Y.), ISSN 0036-8075, 5/2017, Volume 356, Issue 6338, pp. 617 - 624
The integration of endocytic routes is critical to regulate receptor signaling. A non-clathrin endocytic pathway (NCE) of the epidermal growth factor receptor... 
Journal Article
PLoS Genetics, ISSN 1553-7390, 10/2009, Volume 5, Issue 10, pp. e1000675 - e1000675
Journal Article
Nature Cell Biology, ISSN 1465-7392, 12/2004, Volume 6, Issue 12, pp. 1173 - 1179
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e56383
Journal Article