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Arabian Journal of Chemistry, ISSN 1878-5352, 11/2016, Volume 9, Issue S2, pp. S1443 - S1449
Multiple sclerosis (MS) is a neurodegenerative disease of the central nervous system (CNS), causes irreversible disability in young adults but the cause and... 
4-AP | Clinical trials | Dalfampridine SR | Multiple sclerosis | Safety | Walking speed | AXONS | PLACEBO | POTASSIUM CHANNELS | SUSTAINED-RELEASE FAMPRIDINE | CHEMISTRY, MULTIDISCIPLINARY | 4-AMINOPYRIDINE | TRIAL | PHARMACOKINETICS | DOUBLE-BLIND | DISABILITY | PROGRESSION
Journal Article
Arabian Journal of Chemistry, ISSN 1878-5352, 02/2017, Volume 10, Issue S1, pp. S1267 - S1275
Reduced levels of γ-aminobutyric acid (GABA) are cause of quite a many diseases, and it cannot be directly introduced into the body to enhance its level... 
GABA | Docking studies | ABAT | GABA inhibitors | Aminobutyrate transaminase | Homology modeling | ACID | RECEPTOR | CHEMISTRY, MULTIDISCIPLINARY | DEFICIENCY | NEUROTRANSMITTER | GASTROESOPHAGEAL-REFLUX | AMINOTRANSFERASE | DISEASE | LOWER ESOPHAGEAL SPHINCTER | ASSOCIATION | BRAIN | Enzymes | Regulation | Aminotransferases | Properties | Testing
Journal Article
Arabian Journal of Chemistry, ISSN 1878-5352, 02/2017, Volume 10, Issue S1, pp. S1022 - S1031
The oxadiazole pharmacophore is considered a viable lead structure for the synthesis of more efficacious and broad spectrum antimicrobial agents. The... 
Schiff bases | 1,3,4-Oxadiazoles | Antifungal | Antioxidant activity | Antibacterial | Biological assays | Lipophilicity | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Arabian Journal of Chemistry, ISSN 1878-5352, 07/2014, Volume 7, Issue 3, pp. 287 - 291
In the present study novel derivatives of 4-thiazolidinone were prepared from biphenyl-4-carboxylic acid and evaluated for their antimicrobial activity against... 
Hydrazones | 4-Thiazolidinone | Antibacterial and antifungal activity | 4-THIAZOLIDINONES | DESIGN | ANTIINFLAMMATORY AGENTS | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Journal Article
Arabian Journal of Chemistry, ISSN 1878-5352, 02/2017, Volume 10, p. S1022-S1031
The oxadiazole pharmacophore is considered a viable lead structure for the synthesis of more efficacious and broad spectrum antimicrobial agents. The... 
Drugs | Heterocyclic compounds | Structure-activity relationship (Pharmacology) | Anti-infective agents | Properties | Structure-activity relationships | Testing
Journal Article
Current topics in medicinal chemistry, 01/2019
5α-Reductase (5AR) a NADPH dependent enzyme is expressed in most of the prostate epithelial cells. By converting testosterone (T) into more potent androgen... 
Journal Article
Toxicology Letters, ISSN 0378-4274, 08/2013, Volume 221, pp. S94 - S94
Journal Article
Arabian Journal of Chemistry, ISSN 1878-5352, 11/2014, Volume 7, Issue 5, pp. 666 - 671
In this study a series of new mannich bases were synthesized and characterized by elemental and spectral (IR, H NMR, C NMR) studies. All the synthesized... 
Antifungal activity | Mannich bases | Antibacterial | Isoniazid | HYDRAZONES | ACID HYDRAZIDE | AGENTS | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Journal of the Serbian Chemical Society, ISSN 0352-5139, 02/2012, Volume 77, Issue 1, pp. 9 - 16
Structural modifications of the front line antitubercular drug isoniazid provide lipophilic adaptations of the drug in which the hydrazide moiety of isoniazid... 
Antimicrobial activity | Mannich bases | Isoniazid | Lipophilicity | 1,3,4-oxadiazoles | DESIGN | isoniazid | BIOLOGICAL EVALUATION | lipophilicity | antimicrobial activity | CHEMISTRY, MULTIDISCIPLINARY | mannich bases
Journal Article
Current Topics in Medicinal Chemistry, ISSN 1568-0266, 08/2013, Volume 13, Issue 16, pp. 2047 - 2061
We herein report the synthesis of 3 beta -substituted amides of 17a-aza-D-homo-4-androsten-17-one (11a-11r) from commercially available Diosgenin as the... 
Journal Article
Journal Article
Mini-Reviews in Medicinal Chemistry, ISSN 1389-5575, 08/2013, Volume 13, Issue 10, pp. 1475 - 1486
Prostate cancer is the most common malignancy among men found to be the second leading cause of male cancer-related mortality due to development of resistance... 
Journal Article
Mini-Reviews in Medicinal Chemistry, ISSN 1389-5575, 05/2013, Volume 13, Issue 6, pp. 915 - 920
Cabazitaxel has recently been approved by FDA for the treatment of docetaxel resistant hormone-refractory prostate cancer. It has been developed by... 
Journal Article
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