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Nature, ISSN 0028-0836, 05/2016, Volume 533, Issue 7604, pp. 477 - 478
Ketamine is an attractive therapeutic, because it can act rapidly and effectively against even treatment-resistant depression3-6 - but the drug has side... 
Antidepressants | Dosage and administration | Ketamine | Studies | Brain | Mental depression | Drug dosages | Psychopharmacology
Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 533, Issue 7604, pp. 477 - 478
The way in which ketamine exerts its antidepressant effects has been perplexing. Evidence that a metabolite of the drug is responsible, and acts on a different... 
ANTIDEPRESSANT | POTENTIATION | MULTIDISCIPLINARY SCIENCES | SYNAPTIC-TRANSMISSION | D-ASPARTATE ANTAGONIST | BLOCKADE | RECEPTOR ANTAGONIST | Ketamine - analogs & derivatives | Animals | Female | Male | Antidepressive Agents - pharmacology | Ketamine - metabolism | Ketamine - pharmacology | Antidepressive Agents - metabolism
Journal Article
Neuron, ISSN 0896-6273, 2005, Volume 48, Issue 2, pp. 289 - 301
Journal Article
Nature Neuroscience, ISSN 1097-6256, 2014, Volume 17, Issue 9, pp. 1146 - 1152
Journal Article
Science, ISSN 0036-8075, 09/2014, Volume 345, Issue 6203, pp. 1494 - 1498
The lateral habenula (LHb), a key regulator of monoaminergic brain regions, is activated by negatively valenced events. Its hyperactivity is associated with... 
DEPRESSION | GLUTAMATE | BEHAVIOR | MULTIDISCIPLINARY SCIENCES | LATERAL HABENULA | GABA | MOSSY FIBER SYNAPSES | CEREBRAL METABOLISM | REWARD | GABAERGIC NEURONS | VENTRAL TEGMENTAL AREA | Physiological aspects | Basal ganglia | Glutamate | Neurotransmitters | Mental depression | Antidepressants | Psychopharmacology | Brain | Regulators | Control | Pathways | Rodents | Depression | Glutamates
Journal Article