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Nature Chemistry, ISSN 1755-4330, 06/2018, Volume 10, Issue 6, pp. 578 - 580
As the most abundant class of biomolecules on Earth, carbohydrates are implicated in a multitude of biological functions. Now, a simple chemical transformation... 
Small Molecule Libraries - chemistry | Glycosylation | Carbohydrates - chemistry | Glycoconjugates - chemistry | Peptides - chemistry | Carbohydrates | Biomolecules | Transformation | Peptides | Molecular chains
Journal Article
Science, ISSN 0036-8075, 05/2016, Volume 352, Issue 6287, pp. 801 - 805
Journal Article
ISSN 1359-7345, 10/2016, Volume 52, Issue 88, pp. 12952 - 12955
A novel method for the introduction of a single protected amine-functional monomer at the chain end of RAFT polymers has been developed. This monomer addition,... 
Journal Article
Australian Journal of Chemistry, ISSN 0004-9425, 2016, Volume 69, Issue 12, pp. 1360 - 1364
Transition metal-mediated arylation chemistry is emerging as a powerful tool for the selective modification of native peptides and proteins, providing new... 
CONJUGATION | CATALYSIS | ALKYLATION | UNPROTECTED PEPTIDES | CHEMISTRY | LIGATION | SELENOCYSTEINE | UNNATURAL AMINO-ACIDS | CHEMISTRY, MULTIDISCIPLINARY | MACROCYCLIZATION | Backbone | Proteins | Covalence | Peptides | Chemical bonds | Amides | Strategy | Selectivity
Journal Article
ChemBioChem, ISSN 1439-4227, 03/2013, Volume 14, Issue 5, p. 559
  The utility of a new [beta]-thiol arginine building block in ligation-desulfurization chemistry has been demonstrated through reactions and kinetic studies... 
Journal Article
Journal Article
Biochemistry, ISSN 0006-2960, 08/2017, Volume 56, Issue 30, pp. 3863 - 3873
Advances in bioconjugation and native protein modification are appearing at a blistering pace, making it increasingly time consuming for practitioners to... 
Journal Article
ISSN 2041-6520, 11/2013, Volume 5, Issue 1, pp. 26 - 266
Peptide ligation-desulfurization chemistry at 2-thiol tryptophan (Trp) is described for the first time. Installation of a thiol auxiliary was achieved through... 
Journal Article
Organic Letters, ISSN 1523-7060, 06/2012, Volume 14, Issue 12, pp. 3142 - 3145
An efficient synthetic route to a suitably protected β-selenol-phenylalanine derivative from commercially available Garner’s aldehyde is described. The... 
EXPRESSED PROTEIN LIGATION | PROLINE LIGATION | REDUCTION | VALINE | CHEMISTRY, ORGANIC | CYSTEINE | DESULFURIZATION | SELENOCYSTEINE | GLYCOPEPTIDES | RESIDUES | PEPTIDE | Phenylalanine - chemical synthesis | Selenium - chemistry | Selenium Compounds - chemical synthesis | Selenium Compounds - chemistry | Molecular Structure | Peptides - chemistry
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2017, Volume 56, Issue 39, pp. 11906 - 11910
Journal Article
Australian Journal of Chemistry, ISSN 0004-9425, 2015, Volume 68, Issue 4, pp. 521 - 537
Native chemical ligation is a powerful tool for the convergent assembly of homogeneous peptide and protein targets from unprotected peptide fragments. The... 
TRYPTOPHAN | EXPRESSED PROTEIN LIGATION | GLYCOPEPTIDE LIGATION | PROLINE LIGATION | NATIVE CHEMICAL LIGATION | SULFENYL HALIDES | CYSTEINE | CHEMOSELECTIVE LIGATION | CHEMISTRY, MULTIDISCIPLINARY | STEREOCONTROLLED SYNTHESIS | HIGHLY EFFICIENT
Journal Article
SCIENCE, ISSN 0036-8075, 01/2016, Volume 351, Issue 6270, pp. 241 - 246
To optimize drug candidates, modern medicinal chemists are increasingly turning to an unconventional structural motif: small, strained ring systems. However,... 
FUNCTIONALIZATION | ORGANIC-CHEMISTRY | POTENT | DESIGN | BIOCONJUGATION | HETEROCYCLES | CLICK CHEMISTRY | MULTIDISCIPLINARY SCIENCES | BRIDGEHEAD | DERIVATIVES | MACROCYCLIZATION | Clinical trials | Nucleophiles | Health aspects | Methods | Drugs | Chemistry | Nitrogen | Carbon
Journal Article
Science, ISSN 0036-8075, 01/2016, Volume 351, Issue 6270, pp. 241 - 246
To optimize drug candidates, modern medicinal chemists are increasingly turning to an unconventional structural motif: small, strained ring systems. However,... 
Chemistry Techniques, Synthetic | Peptides - chemical synthesis | Amination | Pharmaceutical Preparations - chemical synthesis | Chemistry, Pharmaceutical
Journal Article