X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (21) 21
mice (15) 15
index medicus (13) 13
arachidonic acid (12) 12
steroidogenesis (12) 12
cyclic-amp (11) 11
endocrinology & metabolism (10) 10
phosphorylation (10) 10
arachidonic acid - metabolism (9) 9
biochemistry & molecular biology (9) 9
cell biology (8) 8
coenzyme a ligases - metabolism (8) 8
mitochondria - metabolism (8) 8
arachidonic-acid (7) 7
humans (7) 7
male (7) 7
phosphoproteins - metabolism (7) 7
rats (7) 7
steroids - biosynthesis (7) 7
acyl-coa synthetase (6) 6
acyl-coa thioesterase (6) 6
expression (6) 6
leydig cells - metabolism (6) 6
adrenocorticotropic hormone - pharmacology (5) 5
arachidonic-acid release (5) 5
blotting, western (5) 5
cell line (5) 5
cell line, tumor (5) 5
cholesterol (5) 5
cholesterol - metabolism (5) 5
leydig-cells (5) 5
mitochondria (5) 5
protein (5) 5
transfection (5) 5
acth (4) 4
adenosine 3'-5'-cyclic monophosphate (4) 4
adrenal steroidogenesis (4) 4
biochemistry (4) 4
breast cancer (4) 4
camp (4) 4
coenzyme a ligases - genetics (4) 4
cyclic amp - pharmacology (4) 4
dependent protein-kinase (4) 4
enzyme inhibitors - pharmacology (4) 4
kinases (4) 4
ligases (4) 4
lipoxygenase products (4) 4
p43 intermediary (4) 4
phosphoproteins - genetics (4) 4
proteins (4) 4
rat-liver (4) 4
rats, wistar (4) 4
rna, messenger - metabolism (4) 4
star protein (4) 4
steroids (4) 4
stimulated steroidogenesis (4) 4
activation (3) 3
adrenal cortex - metabolism (3) 3
cancer (3) 3
cell proliferation (3) 3
cyclic amp - metabolism (3) 3
cycloheximide - pharmacology (3) 3
dactinomycin - pharmacology (3) 3
enzymes (3) 3
erk1/2 (3) 3
fatty acids - metabolism (3) 3
female (3) 3
gene expression regulation, enzymologic - drug effects (3) 3
gene-expression (3) 3
growth (3) 3
hormone (3) 3
immunohistochemistry (3) 3
inhibition (3) 3
leydig tumor-cells (3) 3
lh/chorionic gonadotropin (3) 3
medicine (3) 3
metabolism (3) 3
mitochondrial proteins (3) 3
molecular sequence data (3) 3
motility (3) 3
multidisciplinary sciences (3) 3
phosphotyrosine phosphatase (3) 3
physiological aspects (3) 3
rat adrenal-gland (3) 3
recombinant proteins - metabolism (3) 3
research article (3) 3
science (3) 3
steroid-synthesis (3) 3
thiolester hydrolases - metabolism (3) 3
transcription (3) 3
tumor cells, cultured (3) 3
unsaturated fatty acids (3) 3
5-lipoxygenase (2) 2
5-lipoxygenase metabolites (2) 2
5-oxo-6,8,11,14-eicosatetraenoic acid (2) 2
8-bromo cyclic adenosine monophosphate - pharmacology (2) 2
acs4 (2) 2
acsl4 (2) 2
activated protein-kinase (2) 2
acute regulatory protein (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 10324 - 13
Acyl-CoA synthetase 4 (ACSL4) overexpression plays a causal role in the aggressiveness of triple negative breast cancer. In turn, a negative correlation has... 
ESTROGEN-RELATED RECEPTOR | ACTIVATION | PROTEIN | INHIBITION | ERR-ALPHA | MULTIDISCIPLINARY SCIENCES | GROWTH | INVERSE AGONIST | SUPPRESSES | CARCINOMA | ROR-ALPHA | Cell proliferation | E2F protein | Transcription factors | Mutagenesis | Base pairs | Breast cancer | Tumor cell lines | Sp1 protein
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, p. e15540
The acyl-CoA synthetase 4 (ACSL4) is increased in breast cancer, colon and hepatocellular carcinoma. ACSL4 mainly esterifies arachidonic acid (AA) into... 
ARACHIDONIC-ACID RELEASE | RAT-LIVER | CYCLIC-AMP | TUMOR PROGRESSION | LEYDIG-CELLS | BENZODIAZEPINE-RECEPTOR PBR | CHOLESTEROL TRANSPORT | EPIDERMAL-GROWTH-FACTOR | BIOLOGY | HUMAN HEPATOCELLULAR-CARCINOMA | STEROIDOGENIC CELLS | Arachidonic Acid - metabolism | Cell Proliferation | Arachidonate 12-Lipoxygenase - metabolism | Coenzyme A Ligases - genetics | Humans | Gene Expression Regulation, Neoplastic | Gene Expression Profiling | Coenzyme A Ligases - metabolism | Breast Neoplasms - enzymology | RNA Interference | Cyclooxygenase 2 - genetics | Lipoxygenases - metabolism | Fatty Acids - metabolism | Arachidonate 12-Lipoxygenase - genetics | Mitochondria - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Gene Expression Regulation, Enzymologic | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cyclooxygenase 2 - metabolism | Cell Line, Tumor | Lipoxygenases - genetics | Cell Movement | Prostaglandins - metabolism | COX-2 inhibitors | Metabolites | Ligases | Cancer cells | Physiological aspects | Breast cancer | Genetic aspects | Arachidonic acid | Drugs | Phosphorylation | Motility | Hepatocellular carcinoma | Biosynthesis | Biochemistry | Metastasis | Kinases | Metastases | Proteins | Liver cancer | Genotype & phenotype | Mitochondria | Cell growth | Colon cancer | Rodents | Cell cycle | Tumorigenesis | Colon | Trends | Enzymes | Aggressive behavior | Intracellular levels | Metabolism | Fatty acids | Esterification | Medicine | Side effects | Breast | Regulation | Cyclooxygenase-2 | Cancer | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e40794
The acyl-CoA synthetase 4 (ACSL4), which esterify mainly arachidonic acid (AA) into acyl-CoA, is increased in breast, colon and hepatocellular carcinoma. The... 
GAMMA AGONISTS | MURINE MODEL | RAT | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | COX-2 INHIBITORS | 5-LIPOXYGENASE | CANCER | EXPRESSION | BREAST | Immunohistochemistry | Arachidonate 5-Lipoxygenase - metabolism | Humans | Tetracycline - pharmacology | Enzyme Inhibitors - pharmacology | Injections, Intraperitoneal | Coenzyme A Ligases - antagonists & inhibitors | Molecular Targeted Therapy | Coenzyme A Ligases - metabolism | Receptors, Progesterone - metabolism | Enzyme Inhibitors - administration & dosage | Xenograft Model Antitumor Assays | Cell Movement - drug effects | Breast Neoplasms - enzymology | Animals | Analysis of Variance | MCF-7 Cells | Breast Neoplasms - pathology | Cyclooxygenase 2 - metabolism | Estrogen Receptor alpha - metabolism | Female | Cell Proliferation - drug effects | Mice | COX-2 inhibitors | Growth | Ligases | Analysis | Physiological aspects | Development and progression | Progesterone | Cancer | Cell proliferation | Phosphorylation | Motility | Laboratories | Estrogens | Xenotransplantation | Clinical trials | Oncology | Hepatocellular carcinoma | Biochemistry | Arachidonic acid | Kinases | Cancer therapies | Metastases | Transfection | Xenografts | Cell cycle | Tumorigenesis | Inhibition | Colon | Trends | Enzymes | Phenotypes | Therapeutic applications | Breast cancer | Metabolism | Esterification | Medicine | Inhibitors | Liquid oxygen | Doxycycline | Breast | In vivo methods and tests | Cyclooxygenase-2 | Synergistic effect | Prostate cancer | Combinatorial analysis | Tumors | Polymorphism
Journal Article
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 01/2019, Volume 159, pp. 52 - 63
[Display omitted] Acyl-CoA synthetase-4 (ACSL4) is an enzyme implicated in estrogen receptor α (ERα) negative regulation and hormone therapy resistance in... 
mTOR pathway | Breast cancer | ACSL4 | ABC transporter | Chemotherapeutic drug resistance | DOXORUBICIN RESISTANCE | SIDE POPULATION | PROTEIN | STEROID-SYNTHESIS | ARACHIDONIC-ACID | INHIBITION | SIGNALING PATHWAY | PHARMACOLOGY & PHARMACY | MULTIDRUG-RESISTANCE | UP-REGULATION | ABCG2
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 09/2016, Volume 117, Issue 9, pp. 2170 - 2181
Journal Article
Journal Article
Journal Article
FRONTIERS IN ENDOCRINOLOGY, ISSN 1664-2392, 06/2016, Volume 7, p. 60
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 11/2011, Volume 52, Issue 11, pp. 1936 - 1948
Acyl-CoA synthetase 4 (ACSL4) is implicated in fatty acid metabolism with marked preference for arachidonic acid (AA). ACSL4 plays crucial roles in... 
Protein tyrosine phosphatases | Leydig cells | Steroidogenesis | Long-chain acyl-CoA synthetases | Proliferation | Arachidonic acid | Breast cancer cells | arachidonic acid | ARACHIDONIC-ACID RELEASE | breast cancer cells | BOVINE ADRENOCORTICAL-CELLS | proliferation | LEYDIG-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | steroidogenesis | DEPENDENT PROTEIN-KINASE | protein tyrosine phosphatases | BREAST-CANCER CELLS | CYCLIC-AMP | long-chain acyl-CoA synthetases | ADRENAL STEROIDOGENESIS | LH/CHORIONIC GONADOTROPIN | HUMAN HEPATOCELLULAR-CARCINOMA | PHOSPHOTYROSINE PHOSPHATASE | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Arachidonic Acid - metabolism | Coenzyme A Ligases - genetics | Humans | Male | Leydig Cells - drug effects | Quinolines - pharmacology | Coenzyme A Ligases - metabolism | Gene Knockdown Techniques | RNA Interference | Leydig Cells - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - deficiency | Plasmids - genetics | Steroids - biosynthesis | Enzyme Inhibitors - pharmacology | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - antagonists & inhibitors | Rats | Phosphoproteins - genetics | Cyclic AMP - pharmacology | Animals | Gene Expression Regulation, Enzymologic - genetics | Arachidonic Acid - biosynthesis | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - genetics
Journal Article
FEBS Letters, ISSN 0014-5793, 08/2007, Volume 581, Issue 21, pp. 4023 - 4028
Recent studies demonstrated the importance of the mitochondrial ATP in the regulation of a novel long-chain fatty acid generation/export system in mitochondria... 
Cholesterol transport | Mitochondria | Steroidogenesis | Arachidonic acid | arachidonic acid |