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1. Full Text The ENTPD1 promoter polymorphism −860 A > G (rs3814159) is associated with increased gene transcription, protein expression, CD39/NTPDase1 enzymatic activity, and thromboembolism risk
by Maloney, James P and Branchford, Brian R and Brodsky, Gary L and Cosmic, Maxwell S and Calabrese, David W and Aquilante, Christina L and Maloney, Kelly W and Gonzalez, Joseph R and Zhang, Weiming and Moreau, Kerrie L and Wiggins, Kerri L and Smith, Nicholas L and Broeckel, Ulrich and Di Paola, Jorge
The FASEB journal, ISSN 0892-6638, 07/2017, Volume 31, Issue 7, pp. 2771 - 2784
purinergic signaling | CD39 Denver | P2Y1 | platelet aggregation | Platelet aggregation | Purinergic signaling | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Genetic Predisposition to Disease | Alternative Splicing | Humans | Middle Aged | Apyrase - metabolism | Genotype | Male | Gene Expression Regulation, Enzymologic - physiology | Venous Thromboembolism - enzymology | Antigens, CD - genetics | Antigens, CD - metabolism | Venous Thromboembolism - genetics | Apyrase - genetics | HEK293 Cells | Adult | Female | Polymorphism, Single Nucleotide | Venous Thromboembolism - metabolism | Haplotypes | Regulators | Transcription | Splicing | Linkage disequilibrium | Oligonucleotides | Adenosine diphosphate | Agglomeration | Gene expression | Ribonucleic acid--RNA | Gene polymorphism | Clotting | Endothelial cells | Proteins | Purines | CD39 antigen | Enzymatic activity | Alleles | Protein expression | Thromboembolism | Platelets | Genotypes | Polymorphism | Index Medicus | Research
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2. Full Text Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial
by Coleman, Robert L and Oza, Amit M and Lorusso, Domenica and Aghajanian, Carol and Oaknin, Ana and Dean, Andrew and Colombo, Nicoletta and Weberpals, Johanne I and Clamp, Andrew and Scambia, Giovanni and Leary, Alexandra and Holloway, Robert W and Gancedo, Margarita Amenedo and Fong, Peter C and Goh, Jeffrey C and O'Malley, David M and Armstrong, Deborah K and Garcia-Donas, Jesus and Swisher, Elizabeth M and Floquet, Anne and Konecny, Gottfried E and McNeish, Iain A and Scott, Clare L and Cameron, Terri and Maloney, Lara and Isaacson, Jeff and Goble, Sandra and Grace, Caroline and Harding, Thomas C and Raponi, Mitch and Sun, James and Lin, Kevin K and Giordano, Heidi and Ledermann, Jonathan A and Buck, M and Dean, A and Friedlander, M L and Goh, J C and Harnett, P and Kichenadasse, G and Scott, C L and Denys, H and Dirix, L and Vergote, I and Elit, L and Ghatage, P and Oza, A M and Plante, M and Provencher, D and Weberpals, J I and Welch, S and Floquet, A and Gladieff, L and Joly, F and Leary, A and Lortholary, A and Lotz, J and Medioni, J and Tredan, O and You, B and El-Balat, A and Hänle, C and Krabisch, P and Neunhöffer, T and Pölcher, M and Wimberger, P and Amit, A and Kovel, S and Leviov, M and Safra, T and Shapira-Frommer, R and Stemmer, S and Bologna, A and Colombo, N and Lorusso, D and Pignata, S and Sabbatini, R F and Scambia, G and Tamberi, S and Zamagni, C and Fong, P C and O'Donnell, A and Gancedo, M Amenedo and Herraez, A Casado and Garcia-Donas, J and Guerra, E M and Oaknin, A and Palacio, I and Romero, I and Sanchez, A and Banerjee, S N and Clamp, A and Drew, Y and Gabra, H G and Jackson, D and Ledermann, J A and McNeish, I A and Parkinson, C and Powell, M and Aghajanian, C and ... and ARIEL3 investigators and ARIEL3 Investigators
The Lancet (British edition), ISSN 0140-6736, 10/2017, Volume 390, Issue 10106, pp. 1949 - 1961
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Double-Blind Method | Follow-Up Studies | Risk Assessment | Humans | Middle Aged | Ovarian Neoplasms - pathology | Neoplasm Recurrence, Local - drug therapy | Survival Rate | Treatment Outcome | Ovarian Neoplasms - mortality | Neoplasm Recurrence, Local - mortality | Indoles - administration & dosage | Poly(ADP-ribose) Polymerase Inhibitors - administration & dosage | Neoplasm Recurrence, Local - pathology | Disease-Free Survival | Maintenance Chemotherapy - methods | Internationality | Ovarian Neoplasms - therapy | Female | Aged | Molecular Targeted Therapy - methods | Clinical trials | Care and treatment | Carcinoma | Drug therapy | Ovarian cancer | Cancer | Analysis | Chemotherapy | Ovarian carcinoma | Platinum | Biomarkers | Mutation | Cancer therapies | Evidence-based medicine | Tumors | Homologous recombination | Central nervous system | Poly(ADP-ribose) | Homology | Genomes | Fallopian tube | Anticancer properties | Metastases | Homologous recombination repair | Randomization | Pain | Motivation | Ribose | Hemoglobin | Alanine | Anemia | Poly(ADP-ribose) polymerase | Adenosine diphosphate | Breast cancer | Patients | Survival | Heterozygosity | Abdomen | Inhibitors | Point mutation | Loss of heterozygosity | Antitumor activity | Aspartate aminotransferase | Peritoneum | Index Medicus | Abridged Index Medicus
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3. Full Text Anti-CD20 Antibody Therapy for B-Cell Lymphomas
by Maloney, David G
The New England journal of medicine, ISSN 0028-4793, 05/2012, Volume 366, Issue 21, pp. 2008 - 2016
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | General aspects | Medical sciences | Antigens, CD20 - immunology | Doxorubicin - therapeutic use | Humans | Middle Aged | Rituximab | Male | Antineoplastic Agents - therapeutic use | Cyclophosphamide - therapeutic use | Antineoplastic Agents - adverse effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Vincristine - therapeutic use | Antibodies, Monoclonal, Murine-Derived - adverse effects | Prednisone - therapeutic use | Antibodies, Monoclonal, Murine-Derived - therapeutic use | Lymphoma, B-Cell - drug therapy | Practice Guidelines as Topic | Case studies | Medical case management | Monoclonal antibodies | Lymphomas | Dosage and administration | Drug therapy | Methods | Chemotherapy | Lymphocytes B | Immunotherapy | CD20 antigen | Antibodies | Cancer therapies | Lymphoma | Cancer | Abdomen | B-cell lymphoma | Index Medicus | Abridged Index Medicus
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4. Full Text Neutrino interaction classification with a convolutional neural network in the DUNE far detector
by Abi, B and Acciarri, R and Acero, M.A and Adamov, G and Adams, D and Adinolfi, M and Filthaut, F and Henry, S.B and Mariani, C and Matthews, J and Miedema, T and Wu, W.T and Zutshi, V and Zwaska, R and DUNE Collaboration and SLAC National Accelerator Lab., Menlo Park, CA (United States) and Brookhaven National Lab. (BNL), Upton, NY (United States) and Los Alamos National Lab. (LANL), Los Alamos, NM (United States) and Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States) and Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States) and Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Physical review. D, ISSN 2470-0010, 2020, Volume 102, Issue 9, pp. 1 - 20
Physical Sciences | Astronomy & Astrophysics | Physics, Particles & Fields | Physics | Science & Technology | Neural networks | Efficiency | Neutrinos | Machine learning | Artificial neural networks | Experiments | Electrons | Muons | INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY | PHYSICS OF ELEMENTARY PARTICLES AND FIELDS
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5. Full Text Unruptured Intracranial Aneurysms — Risk of Rupture and Risks of Surgical Intervention
by Wiebers, David O and Marsh, Richard and The International Study of Unruptured Intracranial Aneurysms Investigators and Int Study Unruptured Intracranial Aneurysms Inv and International Study of Unruptured Intracranial Aneurysms Investigators
The New England journal of medicine, ISSN 0028-4793, 12/1998, Volume 339, Issue 24, pp. 1725 - 1733
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Neurology | Biological and medical sciences | Vascular diseases and vascular malformations of the nervous system | Medical sciences | Subarachnoid Hemorrhage - epidemiology | Prospective Studies | Age Factors | Rupture, Spontaneous - epidemiology | Humans | Middle Aged | Risk Factors | Aneurysm, Ruptured - epidemiology | Probability | Male | Aneurysm, Ruptured - etiology | Intracranial Aneurysm - complications | Intracranial Aneurysm - surgery | Vascular Surgical Procedures - adverse effects | Vascular Surgical Procedures - mortality | Adolescent | Aged, 80 and over | Subarachnoid Hemorrhage - etiology | Adult | Female | Aged | Retrospective Studies | Intracranial Aneurysm - pathology | Intracranial aneurysms | Prognosis | Health care | Aneurysms | Hemorrhage | Index Medicus | Abridged Index Medicus
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6. Full Text Autologous or Reduced-Intensity Conditioning Allogeneic Hematopoietic Cell Transplantation for Chemotherapy-Sensitive Mantle-Cell Lymphoma: Analysis of Transplantation Timing and Modality
by Timothy S. Fenske and Mei-Jie Zhang and Jeanette Carreras and Ernesto Ayala and Linda J. Burns and Amanda Cashen and Luciano J. Costa and César O. Freytes and Robert P. Gale and Mehdi Hamadani and Leona A. Holmberg and David J. Inwards and Hillard M. Lazarus and Richard T. Maziarz and Reinhold Munker and Miguel-Angel Perales and David A. Rizzieri and Harry C. Schouten and Sonali M. Smith and Edmund K. Waller and Baldeep M. Wirk and Ginna G. Laport and David G. Maloney and Silvia Montoto and Parameswaran N. Hari
Journal of clinical oncology, ISSN 0732-183X, 02/2014, Volume 32, Issue 4, pp. 273 - +
Life Sciences & Biomedicine | Oncology | Science & Technology | Hematologic and hematopoietic diseases | Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis | Biological and medical sciences | Medical sciences | Tumors | Recurrence | Lymphoma, Mantle-Cell - surgery | Humans | Middle Aged | Kaplan-Meier Estimate | Lymphoma, Mantle-Cell - drug therapy | Male | Transplantation, Autologous | Treatment Outcome | Hematopoietic Stem Cell Transplantation - mortality | Disease Progression | Transplantation, Homologous | Lymphoma, Mantle-Cell - mortality | Disease-Free Survival | Time Factors | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adult | Female | Aged | Hematopoietic Stem Cell Transplantation - methods | Transplantation Conditioning - methods | Index Medicus | Bone2 | ORIGINAL REPORTS
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7. Full Text Anti-CD19 CAR T cell therapy for lymphoma - off to the races
by Maloney, David G
Nature reviews. Clinical oncology, ISSN 1759-4774, 05/2019, Volume 16, Issue 5, pp. 279 - 280
Life Sciences & Biomedicine | Oncology | Science & Technology | Antigen receptors, T cell | Receptors | Care and treatment | Pharmacology, Experimental | Physiological aspects | Dosage and administration | Lymphomas | Research | Drug therapy | T cells | Testing | Cancer | Chimeric antigen receptors | CD19 antigen | Lymphocytes B | Clinical trials | Lymphocytes T | Lymphoma | B-cell lymphoma | Index Medicus
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8. Full Text Autologous haemopoietic stem-cell transplantation followed by allogeneic or autologous haemopoietic stem-cell transplantation in patients with multiple myeloma (BMT CTN 0102): a phase 3 biological assignment trial
by Krishnan, Amrita, MD and Pasquini, Marcelo C, MD and Logan, Brent, PhD and Stadtmauer, Edward A, Prof and Vesole, David H, Prof and Alyea, Edwin, MD and Antin, Joseph H, Prof and Comenzo, Raymond, Prof and Goodman, Stacey, Prof and Hari, Parameswaran, MD and Laport, Ginna, MD and Qazilbash, Muzaffar H, MD and Rowley, Scott, Prof and Sahebi, Firoozeh, MD and Somlo, George, MD and Vogl, Dan T, MD and Weisdorf, Daniel, Prof and Ewell, Marian, ScD and Wu, Juan, MS and Geller, Nancy L, PhD and Horowitz, Mary M, MD and Giralt, Sergio, Prof and Maloney, David G, Prof and on behalf of the Blood Marrow Transplant Clinical Trials Network (BMT CTN) and Blood Marrow Transplant Clinical and Blood Marrow Transplant Clinical Trials Network (BMT CTN)
The lancet oncology, ISSN 1470-2045, 2011, Volume 12, Issue 13, pp. 1195 - 1203
Hematology, Oncology and Palliative Medicine | Life Sciences & Biomedicine | Oncology | Science & Technology | Myeloablative Agonists - therapeutic use | Multiple Myeloma - mortality | United States | Humans | Middle Aged | Male | Transplantation, Autologous | Hematopoietic Stem Cell Transplantation - mortality | Transplantation, Homologous | Young Adult | Multiple Myeloma - drug therapy | Time Factors | Hematopoietic Stem Cell Transplantation - adverse effects | Adult | Female | Multiple Myeloma - surgery | Dexamethasone - administration & dosage | Multiple Myeloma - diagnosis | Risk Assessment | Risk Factors | Kaplan-Meier Estimate | Proportional Hazards Models | Graft vs Tumor Effect | Survival Rate | Treatment Outcome | Thalidomide - administration & dosage | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Care and treatment | Oncology, Experimental | Multiple myeloma | Stem cells | Transplantation | Research | Universities and colleges | Cancer | Index Medicus
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9. Full Text Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120)
by Sparks, Steven M and Chen, Grace and Collins, Jon L and Danger, Dana and Dock, Steven T and Jayawickreme, Channa and Jenkinson, Stephen and Laudeman, Christopher and Leesnitzer, M. Anthony and Liang, Xi and Maloney, Patrick and McCoy, David C and Moncol, David and Rash, Vincent and Rimele, Thomas and Vulimiri, Padmaja and Way, James M and Ross, Sean
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 07/2014, Volume 24, Issue 14, pp. 3100 - 3103
Free fatty acid receptor 4 agonist | FFA4 | GPR120 | Free fatty acid receptor 4 | Free fatty acid receptor 4 antagonist | Cell Line | Insulin - agonists | Sulfonamides - chemistry | Humans | Structure-Activity Relationship | Receptors, G-Protein-Coupled - agonists | Sulfonamides - pharmacology | Dose-Response Relationship, Drug | Sulfonamides - chemical synthesis | Animals | HEK293 Cells | Mice | Molecular Structure | Fatty acids | Index Medicus
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