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Journal of Neurochemistry, ISSN 0022-3042, 06/2014, Volume 129, Issue 6, pp. 895 - 897
Read the full article ‘Interferon‐γinduces leucine‐rich repeat kinase LRRK2 via extracellular signal‐regulated kinase ERK5 in macrophages’ on page 980. 
ASSOCIATION | NEUROSCIENCES | BIOCHEMISTRY & MOLECULAR BIOLOGY | ERK5 | Protein-Serine-Threonine Kinases - biosynthesis | Mitogen-Activated Protein Kinase 7 - physiology | Humans | Interferon-gamma - pharmacology | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Macrophages - enzymology | Immune response
Journal Article
Scientific Reports, ISSN 2045-2322, 10/2016, Volume 6, Issue 1, p. 35106
Journal Article
BIOCHEMICAL SOCIETY TRANSACTIONS, ISSN 0300-5127, 04/2019, Volume 47, Issue 2, pp. 651 - 661
The past two decades in research has revealed the importance of leucine-rich repeat kinase 2 (LRRK2) in both monogenic and sporadic forms of Parkinson's... 
KINASE 2 LRRK2 | LEWY BODY PATHOLOGY | AUTOSOMAL-DOMINANT PARKINSONISM | RISK-FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | MUTATION | G2019S | ALPHA-SYNUCLEIN | GENOME-WIDE ASSOCIATION | COMPREHENSIVE ANALYSIS | RAB10 PHOSPHORYLATION
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e47784
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are a common cause of autosomal dominant familial Parkinson's disease (PD). LRRK2 encodes a... 
DISEASE-ASSOCIATED MUTATIONS | KINASE-ACTIVITY | ACTIVATION | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | LINK | GTP-BINDING | DOPAMINERGIC NEURON | PARKINSONS-DISEASE | Phosphorylation | Humans | Male | Phosphoproteins - metabolism | Brain - metabolism | Multiprotein Complexes - metabolism | HEK293 Cells | Aged, 80 and over | Female | Mammals - metabolism | Parkinson Disease - pathology | Protein-Serine-Threonine Kinases - genetics | Rats | Mutation - genetics | Subcellular Fractions - metabolism | Phosphothreonine - metabolism | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Animals | Carrier Proteins - metabolism | Parkinson Disease - enzymology | Brain - pathology | Aged | Mice | Protein Processing, Post-Translational | Adaptor Proteins, Signal Transducing - metabolism | Brain | Usage | Parkinson's disease | Gene mutations | Leucine zipper | Genetic aspects | Research | Complex formation | Toxicity | Parkinsons disease | Leucine | Kinases | Mammalian cells | Proteins | Neurotoxicity | Enzymatic activity | Neurodegeneration | Rodents | Animal tissues | Post-translation | Physiology | Life sciences | LRRK2 protein | Localization | Coordination compounds | Movement disorders | Neurodegenerative diseases | Drosophila | Transgenic mice | Mammals | Substrates | Neurology | Insects | Mutation | Initiation factor eIF-4E | Guanosinetriphosphatase
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 09/2019, Volume 129, p. 67
Several previous studies have linked the Parkinson's disease (PD) gene LRRK2 to the biology of microglia cells. However, the precise ways in which LRRK2... 
RNA sequencing | Medical research | Oxidative stress | Enzymes | Messenger RNA | Analysis | Genes | Medicine, Experimental | Genetic research | Superoxide | Gene expression | Mitogens
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2014, Volume 35, Issue 5, pp. 1111 - 1115
Journal Article
Journal Article
Molecular Neurodegeneration, ISSN 1750-1326, 09/2017, Volume 12, Issue 1, pp. 70 - 17
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 10/2011, Volume 122, Issue 4, pp. 415 - 428
Journal Article
Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, p. 5827
LRRK2, a gene relevant to Parkinson's disease, encodes a scaffolding protein with both GTPase and kinase activities. LRRK2 protein is itself phosphorylated and... 
PROTEIN | INHIBITION | MULTIDISCIPLINARY SCIENCES | 14-3-3 BINDING | PARKINSONS-DISEASE | RNA, Small Interfering - genetics | Phosphorylation | Membrane Glycoproteins - metabolism | Humans | Casein Kinase Ialpha - genetics | Neurons - cytology | Cerebral Cortex - cytology | Corpus Striatum - cytology | trans-Golgi Network - metabolism | Membrane Glycoproteins - antagonists & inhibitors | HEK293 Cells | Phloroglucinol - pharmacology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Rho Guanine Nucleotide Exchange Factors - antagonists & inhibitors | Indoles - pharmacology | Benzamides - pharmacology | Cerebral Cortex - drug effects | Rho Guanine Nucleotide Exchange Factors - metabolism | Neurons - drug effects | Corpus Striatum - enzymology | Protein-Serine-Threonine Kinases - metabolism | Cerebral Cortex - enzymology | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Casein Kinase Ialpha - antagonists & inhibitors | Imidazoles - pharmacology | Rho Guanine Nucleotide Exchange Factors - genetics | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Membrane Glycoproteins - genetics | Mice, Knockout | trans-Golgi Network - drug effects | Animals | Neurons - enzymology | Mice | Protein Kinase Inhibitors - pharmacology | Primary Cell Culture | Casein Kinase Ialpha - metabolism | Phloroglucinol - analogs & derivatives | RNA, Small Interfering - metabolism
Journal Article