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Acta Neuropathologica, ISSN 0001-6322, 2014, Volume 127, Issue 6, pp. 861 - 879
Immunotherapeutic approaches are currently in the spotlight for their potential as disease-modifying treatments for neurodegenerative disorders. The discovery... 
Parkinson's disease | AFFITOME | Immunotherapy | Vaccination | Alpha-synuclein | AFFITOPE | HUMAN ALPHA-SYNUCLEIN | ALZHEIMERS-DISEASE | PATHOLOGY | NEUROSCIENCES | NEURODEGENERATIVE DISEASES | CLINICAL NEUROLOGY | EXPLORATORY ACTIVITY | AFFITOME (R) | A-BETA | MICE | MOTOR COORDINATION | LEWY-BODY-DISEASE | TRANSGENIC MOUSE MODEL | AFFITOPE (R) | Parkinson Disease - therapy | Memory Disorders - physiopathology | Motor Activity - physiology | T-Lymphocytes - physiology | Putamen - pathology | Humans | Caudate Nucleus - pathology | Nerve Degeneration - physiopathology | Axons - physiology | Synapses - pathology | Caudate Nucleus - physiopathology | Lewy Body Disease - therapy | Microglia - physiology | Vaccination - methods | Putamen - physiopathology | Microglia - pathology | alpha-Synuclein - genetics | T-Lymphocytes - pathology | Memory Disorders - pathology | Disease Models, Animal | Parkinson Disease - pathology | Synapses - physiology | Mice, Inbred C57BL | Lewy Body Disease - pathology | Antibodies - cerebrospinal fluid | Mice, Transgenic | Clinical Trials as Topic | Parkinson Disease - physiopathology | Nerve Degeneration - pathology | Animals | Axons - pathology | Memory Disorders - therapy | Antibodies - blood | alpha-Synuclein - metabolism | Lewy Body Disease - physiopathology | Nerve Degeneration - therapy | Oligomers | Platelet-derived growth factor | Peptides | Clinical trials | Genetic engineering | T cells
Journal Article
Movement Disorders, ISSN 0885-3185, 02/2016, Volume 31, Issue 2, pp. 214 - 224
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 12954 - 10
Application of in vitro transcribed (IVT) messenger ribonucleic acid (mRNA) is an increasingly popular strategy to transiently produce proteins as therapeutics... 
THERAPEUTICS | GENE GUN | STABILITY | DNA | MULTIDISCIPLINARY SCIENCES | BASAL-CELL CARCINOMA | INTRALESIONAL INTERFERON-ALPHA-2B | CAP ANALOGS | ACTINIC KERATOSES | MAMMALIAN-CELLS | DELIVERY | Explants | α-Interferon | Transfection | Media (culture) | Secretion | Melanoma | mRNA | Interferon | Skin tests | Skin cancer
Journal Article
Genes and Development, ISSN 0890-9369, 11/2002, Volume 16, Issue 22, pp. 2958 - 2970
The mammalian kidney develops in three successive steps from the initial pronephros via the mesonephros to the adult metanephros. Although the nephric lineage... 
Genetic redundancy | Lineage specification | Pax8 | Mesenchymal-epithelial transition | Pax2 | Kidney development | lineage specification | genetic redundancy | METANEPHRIC MESENCHYME | DEVELOPING EXCRETORY SYSTEM | INTERMEDIATE MESODERM | DEVELOPMENTAL BIOLOGY | THYROID-GLAND | RETROVIRAL VECTORS | MICE LACKING GDNF | kidney development | mesenchymal-epithelial transition | GENETICS & HEREDITY | GENE-EXPRESSION | CHICK-EMBRYO | GROWTH-FACTOR | Kidney - embryology | Homeodomain Proteins - metabolism | Molecular Sequence Data | Apoptosis - genetics | Male | Mesoderm - cytology | Mesonephros - metabolism | DNA-Binding Proteins - metabolism | Gene Expression Regulation, Developmental | Mice, Mutant Strains | Trans-Activators - genetics | Female | Proto-Oncogene Proteins c-ret | Cell Differentiation | PAX2 Transcription Factor | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Drosophila Proteins | Paired Box Transcription Factors | Mice, Inbred C57BL | Gene Silencing | Urogenital System - embryology | Proto-Oncogene Proteins - genetics | Kidney - cytology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Chick Embryo | Homeodomain Proteins - genetics | Nuclear Proteins | Transcription Factors - metabolism | Cell Lineage | Urogenital System - metabolism | Animals | Mesonephros - embryology | Kidney - abnormalities | Receptor Protein-Tyrosine Kinases - genetics | LIM-Homeodomain Proteins | Trans-Activators - metabolism | Mice | PAX8 Transcription Factor | Epithelial cells | Analysis | Genetic research | Physiological aspects | Genetic aspects | Nephrotic syndrome | Genetic transcription | Research | Genetic regulation | Research Paper
Journal Article
Molecular Neurodegeneration, ISSN 1750-1326, 03/2015, Volume 10, Issue 1, p. 10
Journal Article
Human Vaccines, ISSN 1554-8600, 11/2010, Volume 6, Issue 11, pp. 948 - 952
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 07/2014, Volume 128, Issue 1, p. 67
Pyroglutamylated amyloid-[beta] (pE(3)-A[beta]) has been suggested to play a major role in Alzheimer's disease (AD) pathogenesis as amyloid-[beta] (A[beta])... 
Oligomers | Brain | Activities of daily living | Alzheimer's disease | Analysis | Neurophysiology
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 2012, Volume 33, pp. S20 - S21
Journal Article
Journal of Neuroinflammation, ISSN 1742-2094, 12/2015, Volume 12, Issue 1
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2011, Volume 7, Issue 4, pp. S793 - S793
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 09/2019, Volume 15, Issue 9, p. 1133
Immunotherapeutic approaches targeting amyloid [beta] (A[beta]) protein and tau in Alzheimer's disease and [alpha]-synuclein ([alpha]-syn) in Parkinson's... 
Neurosciences | Neurons | Immunotherapy | Analysis | Alzheimer's disease
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2015, Volume 10, Issue 1
Recent evidence suggests Alzheimer-Disease (AD) to be driven by aggregated A beta. Capitalizing on the mechanism of molecular mimicry and applying several... 
Max planck ring 2 | APP TRANSGENIC MICE | NEURAL STEM-CELLS | IMMUNOTHERAPY | FAMILY-MEMBERS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | DISEASE | SECRETED FORM | AMYLOID-PRECURSOR-PROTEIN | PROLIFERATION | BRAIN
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 09/2019, Volume 15, Issue 9, pp. 1133 - 1148
Immunotherapeutic approaches targeting amyloid β (Aβ) protein and tau in Alzheimer's disease and α-synuclein (α-syn) in Parkinson's disease are being developed... 
Immunization | Alzheimer's disease | Immunotherapy | α-synuclein | AFFITOPE | Dementia with Lewy bodies | BODY DISEASE | ALZHEIMERS-DISEASE | TAU | PATHOLOGY | alpha-synuclein | NEURODEGENERATIVE DISEASES | CLINICAL NEUROLOGY | DEGENERATION | MULTIPLE SYSTEM ATROPHY | A-BETA | PARKINSON-DISEASE | TRANSGENIC MOUSE MODEL | AFFITOPE (R)
Journal Article