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Nature Reviews Endocrinology, ISSN 1759-5029, 2017, Volume 14, Issue 2, pp. 72 - 74
Journal Article
Lancet, The, ISSN 0140-6736, 2013, Volume 381, Issue 9881, pp. 1905 - 1915
Journal Article
Diabetes, ISSN 0012-1797, 12/2017, Volume 66, Issue 12, pp. 2937 - 2939
Two major unanswered questions related to the pathogenesis of type 1 diabetes (T1D) prevent progress in our ability to intervene in disease development: (1)... 
INTERLEUKIN-2 | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | PERFORIN | MICE | IL-2 | SIGNATURE | CELL-DEATH | Enzymes | Pathogenesis | Diabetes mellitus | Transgenic mice | Cytotoxicity | Insulin | Immunological tolerance | Cells | Rodents | Tryptase | Diabetes | Pancreas | Immune system | Apoptosis
Journal Article
NATURE REVIEWS ENDOCRINOLOGY, ISSN 1759-5029, 02/2018, Volume 14, Issue 2, pp. 73 - 74
Extracellular danger-associated molecular patterns signal to NOD-like receptors, but the exact signalling pathways remain unclear. The inflammasomes, a... 
ENDOCRINOLOGY & METABOLISM | Glucose metabolism | Inflammation | Immune response | Research | Cells | Aging
Journal Article
Diabetes Care, ISSN 0149-5992, 12/2017, Volume 40, Issue 12, pp. 1771 - 1778
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 10/2010, Volume 11, Issue 10, pp. 881 - 883
IAPP, a hormone secreted together with insulin and deposited in pancreatic islets in type 2 diabetes, can induce macrophage processing of interleukin 1 linked... 
INTERLEUKIN-1 | OXIDATIVE STRESS | ACTIVATION | PROTEIN | MELLITUS | IMMUNOLOGY | Interleukin-1 - metabolism | Macrophages - metabolism | Animals | Amyloid - metabolism | Islet Amyloid Polypeptide | Islets of Langerhans - metabolism | Diabetes Mellitus, Type 2 - immunology | Humans | Islets of Langerhans - immunology | Macrophages - immunology
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 04/2007, Volume 356, Issue 15, pp. 1517 - 1526
The expression of interleukin-1–receptor antagonist is reduced in pancreatic islets in type 2 diabetes, and high glucose concentrations induce interleukin-1β... 
INSULIN | MEDICINE, GENERAL & INTERNAL | HUMAN PANCREATIC-ISLETS | OBESITY | GLUCOSE | BETA-CELL APOPTOSIS | DISEASE | MUSCLE | EXPRESSION | RECEPTOR ANTAGONIST | NIDDM | Recombinant Proteins - therapeutic use | Insulin-Secreting Cells - secretion | Glucose Transporter Type 4 - metabolism | Glycated Hemoglobin A - metabolism | Humans | Middle Aged | Male | Diabetes Mellitus, Type 2 - metabolism | RNA, Messenger - metabolism | Heat-Shock Proteins - genetics | Insulin Resistance - physiology | Interleukin-6 - blood | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Female | Interleukin 1 Receptor Antagonist Protein - pharmacology | Body Mass Index | Glucose Tolerance Test | Double-Blind Method | Glucose Transporter Type 4 - genetics | Heat-Shock Proteins - metabolism | C-Reactive Protein - secretion | Recombinant Proteins - pharmacology | Transcription Factors - genetics | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Interleukin 1 Receptor Antagonist Protein - therapeutic use | Insulin-Secreting Cells - drug effects | Interleukin 1 Receptor Antagonist Protein - adverse effects | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Receptors, Interleukin-1 - antagonists & inhibitors | Type 2 diabetes | Interleukin-1 | Research | Drug therapy | Pancreas | Diabetes | Apoptosis | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
Nature reviews. Immunology, ISSN 1474-1733, 09/2019
Type 1 and type 2 diabetes are characterized by chronic inflammation; both diseases involve pancreatic islet inflammation, while systemic low-grade... 
Journal Article