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PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 12, p. e14191
Journal Article
Cell, ISSN 0092-8674, 02/2012, Volume 148, Issue 3, pp. 421 - 433
Journal Article
Diabetes, ISSN 0012-1797, 10/2002, Volume 51, Issue 10, pp. 2929 - 2935
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2015, Volume 112, Issue 17, pp. E2253 - E2262
Although inhibition of cyclic nucleotide phosphodiesterase type 3 (PDE3) has been reported to protect rodent heart against ischemia/reperfusion (I/R) injury,... 
Protein kinase A | Signalosome | Ischemia/reperfusion injury | Membrane repair | PDe3B-/- Mice | PERMEABILITY TRANSITION PORE | signalosome | INNER MITOCHONDRIAL-MEMBRANE | KINASE-A | ischemia/reperfusion injury | CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES | MULTIDISCIPLINARY SCIENCES | CA2+-ACTIVATED K+ CHANNELS | CARDIAC MYOCYTES | membrane repair | GLYCOGEN-SYNTHASE KINASE-3-BETA | ISCHEMIA-REPERFUSION INJURY | SIGNAL-TRANSDUCTION | SMOOTH-MUSCLE-CELLS | PDE3B(-/-) mice | protein kinase A | Myocardial Infarction - genetics | Caveolin 3 - genetics | Mitochondria, Heart - metabolism | Mitochondria, Heart - pathology | Quinolones - pharmacology | Myocardial Reperfusion Injury - enzymology | Mitochondrial Membrane Transport Proteins - genetics | Cyclic Nucleotide Phosphodiesterases, Type 3 - deficiency | Myocardial Reperfusion Injury - pathology | Cyclic AMP-Dependent Protein Kinases - genetics | Myocardial Infarction - pathology | Cyclic AMP - genetics | Cyclic Nucleotide Phosphodiesterases, Type 3 - metabolism | Mitochondria, Heart - genetics | Cyclic AMP - metabolism | Myocardial Reperfusion Injury - genetics | Connexin 43 - genetics | Myocardial Infarction - enzymology | Cyclic AMP-Dependent Protein Kinases - metabolism | Mitochondrial Membrane Transport Proteins - metabolism | Connexin 43 - metabolism | Phosphodiesterase Inhibitors - pharmacology | Myocardium - pathology | Mice, Knockout | Mitochondrial Membrane Transport Proteins - pharmacology | Myocardium - enzymology | Animals | Mice | Myocardial Infarction - prevention & control | Caveolin 3 - metabolism | Myocardial Reperfusion Injury - prevention & control | Enzymes | Development and progression | Genetic aspects | Regulation | Phosphodiesterases | Health aspects | Reperfusion injury | Biological Sciences | PNAS Plus | PDE3B | reperfusion injury | mice | ischemia
Journal Article
Biochemical Journal, ISSN 0264-6021, 12/2009, Volume 424, Issue 3, pp. 399 - 410
In adipocytes, PDE3B (phosphodiesterase 3B) is an important regulatory effector in signalling pathways controlled by insulin and cAMP-increasing hormones.... 
Caveolin-1 | adrenergic receptor | Phosphodiesterase 3 (PDE3) | Adipocyte | Protein kinase A (PKA) | Insulin
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2011, Volume 286, Issue 29, pp. 26238 - 26249
Cyclic nucleotide phosphodiesterase 3 (PDE3) is an important regulator of cyclic adenosine monophosphate (cAMP) signaling within the cardiovascular system. In... 
MIGRATION | INSULIN REGULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MESANGIAL CELLS | NITRIC-OXIDE | ATHEROSCLEROSIS | GROWTH-FACTOR | NUCLEOTIDE PHOSPHODIESTERASES | DIFFERENTIAL REGULATION | EXPRESSION | CAMP | Cell Cycle - genetics | Gene Expression Regulation, Enzymologic - drug effects | RNA, Small Interfering - genetics | Cyclic Nucleotide Phosphodiesterases, Type 3 - genetics | Muscle, Smooth, Vascular - metabolism | Male | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Cyclic Nucleotide Phosphodiesterases, Type 3 - deficiency | Phosphorylation - genetics | MAP Kinase Signaling System - genetics | Biocatalysis - drug effects | Gene Deletion | Cell Cycle Proteins - genetics | DNA - biosynthesis | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Muscle, Smooth, Vascular - drug effects | Cyclic AMP-Dependent Protein Kinases - metabolism | Cell Cycle Proteins - metabolism | Cells, Cultured | Platelet-Derived Growth Factor - pharmacology | Gene Knockout Techniques | Muscle, Smooth, Vascular - cytology | Proto-Oncogene Proteins c-raf - metabolism | Animals | MAP Kinase Signaling System - drug effects | Gene Expression Regulation, Enzymologic - genetics | Cyclic AMP Response Element-Binding Protein - metabolism | Dual Specificity Phosphatase 1 - metabolism | Cell Proliferation - drug effects | Mice | Cell Cycle - drug effects | Muscle, Smooth, Vascular - enzymology | Mitogen-Activated Protein Kinases - metabolism | MAP Kinases (MAPKs) | Protein Kinase A (PKA) | CREB | Cell Cycle | Signal Transduction | Retinoblastoma (Rb) | Cell Growth | ERK Signaling | VSMC | Cyclic AMP (cAMP) | Cell Biology
Journal Article
Scientific Reports, ISSN 2045-2322, 01/2017, Volume 7, Issue 1, p. 40445
Understanding mechanisms by which a population of beige adipocytes is increased in white adipose tissue (WAT) reflects a potential strategy in the fight... 
FATTY-ACID OXIDATION | ENERGY HOMEOSTASIS | ADAPTIVE THERMOGENESIS | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTIONAL CONTROL | DEPENDENT PROTEIN-KINASE | TUMOR-SUPPRESSOR | DEFICIENT MICE | METABOLIC-CONTROL | BROWN FAT | Epididymis - metabolism | AMP-Activated Protein Kinases - metabolism | Adipose Tissue, White - metabolism | Male | Gene Knockdown Techniques | Cyclic Nucleotide Phosphodiesterases, Type 3 - deficiency | Organelle Biogenesis | Female | Cyclic Nucleotide Phosphodiesterases, Type 3 - metabolism | Weight Gain | Cyclic AMP - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Signal Transduction | Mitochondria - metabolism | 3T3-L1 Cells | Mice, Knockout | Obesity - metabolism | Phenotype | Animals | Thermogenesis | Energy Metabolism | Adipocytes - metabolism | Obesity - prevention & control | Mice | Enzyme Activation | Adipose Tissue, Beige - metabolism | Protein kinase A | Energy metabolism | Adipose tissue | Body weight | Liver | Homeostasis | Nucleotides | Adipocytes | Kinases | AMP-activated protein kinase | High fat diet | Mitochondria | Rodents | Cyclic GMP | Oxidation | Pancreas | Phosphodiesterase | Obesity | 3',5'-Cyclic-nucleotide phosphodiesterase | Diabetes mellitus | Cyclic AMP | Oxygen consumption | Fatty acids | Hydrolysis | Energy balance | Cyclic nucleotides | Diabetes | Metabolic disorders | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article