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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2014, Volume 111, Issue 5, pp. 1766 - 1771
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e83865
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/2016, Volume 138, Issue 4, pp. 1430 - 1445
As part of an effort to examine the utility of antibody–drug conjugates (ADCs) beyond oncology indications, a novel pyrophosphate ester linker was discovered... 
CHEMISTRY, MULTIDISCIPLINARY | SENSITIVE DIPEPTIDE PRODRUGS | Glucocorticoids - chemistry | Diphosphates - chemistry | Esters | Immunoconjugates - chemistry
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 10/2014, Volume 53, Issue 44, pp. 11863 - 11867
Journal Article
American Journal of Gastroenterology, ISSN 0002-9270, 10/2017, Volume 112, p. S1105
Journal Article
Journal Article
Angewandte Chemie, ISSN 1433-7851, 11/2013, Volume 52, Issue 46, pp. 12101 - 12104
  A Fab-ulous killer: An anti-CD3 Fab-folate conjugate that targets cytotoxic Tcells to folate-receptor-positive (FR(+) ) tumors results in efficient killing... 
Killing | Conjugates | Synthesis | Antibodies | Amino acids | Binding sites | Tumors | Cancer
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 11/2013, Volume 52, Issue 46, pp. 12101 - 12104
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 09/2016, Volume 27, Issue 9, p. 2081
  In an effort to examine the utility of antibody-drug conjugates (ADCs) beyond oncology indications, a novel phosphate bridged Cathepsin B sensitive linker... 
Immunoglobulins | Immunology | Proteases | Research & development--R&D | Immunotherapy | Oncology | Steroids
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 09/2016, Volume 27, Issue 9, pp. 2081 - 2081
In an effort to examine the utility of antibody-drug conjugates (ADCs) beyond oncology indications, a novel phosphate bridged Cathepsin B sensitive linker was... 
Journal Article
ACS Chemical Biology, ISSN 1554-8929, 04/2014, Volume 9, Issue 4, pp. 874 - 879
We found that Methanocaldococcus jannaschii DSM2661 tyrosyl-tRNA synthetase (Mj E9RS), specifically evolved to charge its cognate tRNA with the unnatural amino... 
EVOLUTION | RECOGNITION | STRUCTURAL BASIS | TYROSINE | AMINO-ACIDS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | SYNTHETASE | ANTICODON | PROTEINS | PROLINE | Methanocaldococcus - genetics | Methanocaldococcus - enzymology | Amino Acids - chemistry | RNA, Transfer - genetics | Genetic Code - genetics | Amino Acids - genetics | RNA, Transfer - chemistry | Index Medicus | Letters
Journal Article
Angewandte Chemie (International ed. in English), ISSN 1433-7851, 11/2013, Volume 52, Issue 46, pp. 12101 - 12104
Herein, we describe the synthesis of a chemically defined anti-CD3 Fab-folate conjugate that targets cytotoxic T cells to folate receptor positive (FR + )... 
Bi-specific Antibody | T Cells | Folate Receptor | Immunotherapy | Cancer
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2014, Volume 111, Issue 5, p. 1766
  Using an expanded genetic code, antibodies with site-specifically incorporated nonnative amino acids were produced in stable cell lines derived from a CHO... 
Drugs | Amino acids
Journal Article
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