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1. Full Text COPD: Epidemiology, prevalence, morbidity and mortality, and disease heterogeneity
by Mannino, David M
Chest, ISSN 0012-3692, 2002, Volume 121, Issue 5, pp. 121S - 126S
COPD continues to cause a heavy health and economic burden both in the United states and around the world. Some of the risk factors for COPD are well-known and... 
Prevalence | Epidemiology | Mortality | Risk factors | COPD | UNITED-STATES | risk factors | MANAGEMENT | ADULTS | HYPERRESPONSIVENESS | epidemiology | prevalence | OBSTRUCTIVE PULMONARY-DISEASE | RESPIRATORY SYSTEM | mortality | LUNG-DISEASE | ASTHMA | AIRWAYS | BURDEN | AIR-FLOW OBSTRUCTION | CRITICAL CARE MEDICINE | Pulmonary Disease, Chronic Obstructive - mortality | United States - epidemiology | Humans | Risk Factors | Terminology as Topic | Pulmonary Disease, Chronic Obstructive - etiology | Respiratory Mechanics | Pulmonary Disease, Chronic Obstructive - epidemiology
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2. Full Text Counting Costs in COPD : What Do the Numbers Mean?
by Mannino, David M
Chest, ISSN 0012-3692, 01/2015, Volume 147, Issue 1, pp. 3 - 5
UNITED-STATES | RESPIRATORY SYSTEM | CRITICAL CARE MEDICINE | Medicaid - economics | Health Care Costs - statistics & numerical data | Health Expenditures - statistics & numerical data | Humans | Cost of Illness | Female | Male | Medicare - economics | Forecasting | Pulmonary Disease, Chronic Obstructive - economics
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3. Full Text Smoking and Emphysema: Looking Beyond the Cigarette
by Mannino, David M
Chest, ISSN 0012-3692, 11/2015, Volume 148, Issue 5, pp. 1126 - 1127
UNITED-STATES | HEROIN | OBSTRUCTIVE LUNG-DISEASE | RESPIRATORY SYSTEM | COPD | CRITICAL CARE MEDICINE | Heroin - adverse effects | Female | Male | Humans | Pulmonary Emphysema - chemically induced | Substance-Related Disorders - complications
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4. Exactly what is restrictive spirometry capturing?
by Mannino, David M
International Journal of Tuberculosis and Lung Disease, ISSN 1027-3719, 09/2017, Volume 21, Issue 9, pp. 956 - 956
INFECTIOUS DISEASES | PREVALENCE | RESPIRATORY SYSTEM | VITAL CAPACITY
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5. Full Text Biomarkers for chronic obstructive pulmonary disease diagnosis and progression: insights, disappointments and promise
by Mannino, David M
Current Opinion in Pulmonary Medicine, ISSN 1070-5287, 03/2019, Volume 25, Issue 2, pp. 144 - 149
PURPOSE OF REVIEWThis article reviews the status of biomarkers useful in the diagnosis and progression of chronic obstructive pulmonary disease (COPD).... 
TURNOVER | biomarkers | exhaled breath | diagnosis | RISK | MICRORNAS | lung function decline | PREDICT | RESPIRATORY SYSTEM | EMPHYSEMA | EXACERBATIONS | LUNG-FUNCTION DECLINE | OUTCOMES | ASSOCIATION | chronic obstructive pulmonary disease | COPD | Development and progression | Lung diseases, Obstructive | Research | Diagnosis | Biological markers
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6. Full Text Counting Costs in COPD
by Mannino, David M., MD, FCCP
Chest, ISSN 0012-3692, 2015, Volume 147, Issue 1, pp. 3 - 5
Pulmonary/Respiratory
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7. Full Text Is vitamin D's "moment in the sun" behind us?
by Mannino, David M
Chest, ISSN 0012-3692, 2014, Volume 145, Issue 1, pp. 5 - 6
RESPIRATORY SYSTEM | EXACERBATIONS | ASTHMA | PREVALENCE | PULMONARY-DISEASE | COPD | CRITICAL CARE MEDICINE | Vitamin D Deficiency - blood | Humans | Pulmonary Disease, Chronic Obstructive - blood | Female | Male | Vitamin D - analogs & derivatives | Primary Health Care | Vitamin D - blood
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8. Occupational Noise Exposure, Bilateral High-Frequency Hearing Loss, and Blood Pressure
by Wen Qi Gan and David M Mannino
Journal of Occupational and Environmental Medicine, ISSN 1076-2752, 05/2018, Volume 60, Issue 5, p. 462
Objective: The aim of this study was to investigate the relationships between occupational noise exposure and blood pressure using self-reported occupational... 
Hypertension | Medical research | Noise levels | Nutrition | Noise | Exposure | Hearing impairment | Occupational exposure | Blood | Hearing loss | Heart rate | Biomarkers | Occupational health | Blood pressure | Risk exposure
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9. Full Text Reducing COPD Readmissions: Great Promise but Big Problems
by Mannino, David M and Thomashow, Byron
Chest, ISSN 0012-3692, 05/2015, Volume 147, Issue 5, pp. 1199 - 1201
HOSPITAL DISCHARGE | UNITED-STATES | CONTROLLED-TRIAL | OBSTRUCTIVE PULMONARY-DISEASE | RESPIRATORY SYSTEM | ADULTS | RISK | REHOSPITALIZATIONS | EXACERBATION | PROGRAM | CRITICAL CARE MEDICINE | Patient Readmission - statistics & numerical data | Pulmonary Disease, Chronic Obstructive - therapy | Humans
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10. Full Text Factors that impact medical student and house-staff career interest in brain related specialties
by Kamour, Abdulbaset H., DrPH and Han, Dong Y., PsyD and Mannino, David M., MD and Hessler, Amy B., DO and Kedar, Sachin, MD
Journal of the Neurological Sciences, ISSN 0022-510X, 2016, Volume 369, pp. 312 - 317
Abstract Purpose There is a national shortage of physicians in brain related specialties (neurology, neurosurgery and psychiatry), with fewer students training... 
Neurology | Neurophobia | Brain related specialties | Education | Career | SCHOOL | PSYCHIATRY | INDEBTEDNESS | NEUROSCIENCES | ATTITUDES | CLINICAL NEUROLOGY | CHOICE | NEUROLOGY | TRAINEES | PERCEPTIONS | Brain | Specialization | Internship and Residency | Physicians | Students, Medical - psychology | Humans | Female | Male | Psychiatry | Education, Medical, Graduate | Medical students | Vocational interests | Career development | Medical colleges | Neurosciences | Analysis | Vocational guidance
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11. Is it time to move beyond the "o" in early COPD?
by Mannino, David M and Make, Barry J
European Respiratory Journal, ISSN 0903-1936, 12/2015, Volume 46, Issue 6, pp. 1535 - 1537
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death globally [1] and is the focus of primary and tertiary prevention programmes... 
DIAGNOSIS | SPIROMETRY | OBSTRUCTIVE PULMONARY-DISEASE | MANAGEMENT | RESPIRATORY SYSTEM | PRIMARY PREVENTION | Humans | Lung | Pulmonary Disease, Chronic Obstructive
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12. Full Text Global burden of COPD: risk factors, prevalence, and future trends
by Mannino, David M, Dr and Buist, A Sonia, MD
Lancet, The, ISSN 0140-6736, 2007, Volume 370, Issue 9589, pp. 765 - 773
Summary Chronic obstructive pulmonary disease (COPD) continues to be an important cause of morbidity, mortality, and health-care costs worldwide. It is a... 
Internal Medicine | UNITED-STATES | CHRONIC-BRONCHITIS | POPULATION | MEDICINE, GENERAL & INTERNAL | OBSTRUCTIVE PULMONARY-DISEASE | PHARMACOECONOMIC EVALUATION | NUTRITION-EXAMINATION-SURVEY | LUNG-FUNCTION | GOLD CLASSIFICATION | NATIONAL-HEALTH | GLUTATHIONE-S-TRANSFERASE | Severity of Illness Index | Smoking - adverse effects | Environmental Pollutants - adverse effects | Prevalence | Global Health | Occupational Exposure - adverse effects | Humans | Risk Factors | Cost of Illness | Pulmonary Disease, Chronic Obstructive - classification | Male | Pulmonary Disease, Chronic Obstructive - etiology | Forecasting | Pulmonary Disease, Chronic Obstructive - epidemiology | Social Class | Female | Lung diseases, Obstructive | Forecasts and trends | Statistics | Risk factors | Tobacco smoke | High income | Middle income | Respiratory system | Studies | Smoking cessation | Hypotheses | Research methodology | Chronic obstructive pulmonary disease | Health risk assessment | Public health | Chronic illnesses
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13. Full Text Involuntary smoking and asthma severity in children: Data from the Third National Health and Nutrition Examination Survey
by Mannino, David M and Homa, David M and Redd, Stephen C
Chest, ISSN 0012-3692, 2002, Volume 122, Issue 2, pp. 409 - 415
Study objectives: We sought to determine the indicators of asthma severity among children in the United States with high and low levels of tobacco smoke... 
Tobacco smoke pollution | Children | Asthma | UNITED-STATES | POPULATION | PASSIVE SMOKING | COTININE | asthma | tobacco smoke pollution | ENVIRONMENTAL TOBACCO-SMOKE | CHILDHOOD ASTHMA | children | PARENTAL SMOKING | RESPIRATORY SYSTEM | RESPIRATORY HEALTH | EXPOSURE | CRITICAL CARE MEDICINE | Severity of Illness Index | Asthma - physiopathology | Cross-Sectional Studies | Nutrition Surveys | United States | Humans | Child, Preschool | Logistic Models | Male | Regression Analysis | Tobacco Smoke Pollution - adverse effects | Cotinine - blood | Asthma - blood | Adolescent | Adult | Female | Respiratory Function Tests | Child | Asthma - epidemiology | Physiological aspects | Passive smoking | Causes of | Respiratory tract diseases | Asthma in children | Cigarette smoke
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14. Full Text Counting Costs in COPD From the Department of Preventive Medicine and Environmental Health, University of Kentucky College of Public Health
by Mannino, David M
Chest, ISSN 0012-3692, 01/2015, Volume 147, Issue 1, pp. 3 - 5
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15. Full Text An Official American Thoracic Society/European Respiratory Society Statement: Research Questions in Chronic Obstructive Pulmonary Disease
by Celli, B.R and Decramer, M and Wedzicha, J.A and Wilson, K.C and Agustí, A and Criner, G.J and MacNee, W and Make, B.J and Rennard, S.I and Stockley, R.A and Vogelmeier, C and Anzueto, A and Au, D.H and Barnes, P.J and Burgel, P.R and Calverley, P.M and Casanova, C and Clini, E.M and Cooper, C.B and Coxson, H.O and Dusser, D.J and Fabbri, L.M and Fahy, B and Ferguson, G.T and Fisher, A and Fletcher, M.J and Hayot, M and Hurst, J.R and Jones, P.W and Mahler, D.A and Maltais, F and Mannino, D.M and Martinez, F.J and Miravitlles, M and Meek, P.M and Papi, A and Rabe, K.F and Roche, N and Sciurba, F.C and Sethi, S and Siafakas, N and Sin, D.D and Soriano, J.B and Stoller, J.K and Tashkin, D.P and Troosters, T and Verleden, G.M and Verschakelen, J and Vestbo, J and Walsh, J.W and Washko, G.R and Wise, R.A and Wouters, E.F.M and ZuWallack, R.L and ATS/ERS Task Force for COPD Research, the and ATS ERS Task Force COPD Res and ATS/ERS Task Force for COPD Research
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 01/2015, Volume 191, Issue 7, pp. e4 - e27
Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality, and resource use worldwide. The goal of this Official... 
TERM OXYGEN-THERAPY | SMOKING-CESSATION | RESPIRATORY SYSTEM | LUNG-FUNCTION | DOUBLE-BLIND | RANDOMIZED CONTROLLED-TRIAL | POSITIVE-PRESSURE VENTILATION | NONINVASIVE VENTILATION | COMPUTED-TOMOGRAPHY | AIR-FLOW OBSTRUCTION | BODE INDEX | CRITICAL CARE MEDICINE | Societies, Medical - organization & administration | Evidence-Based Medicine - methods | Pulmonary Disease, Chronic Obstructive - diagnosis | Pulmonary Disease, Chronic Obstructive - therapy | Evidence-Based Medicine - organization & administration | Organizational Objectives | United States | Europe | Humans | Policy Making | Biomedical Research - organization & administration | Life Sciences
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16. Lung function impairment in the never-smoker: The search for answers continues
by Mannino, David M
International Journal of Tuberculosis and Lung Disease, ISSN 1027-3719, 09/2015, Volume 19, Issue 9, pp. 1001 - 1001
INFECTIOUS DISEASES | RESPIRATORY SYSTEM | RISK-FACTORS | Tuberculosis - epidemiology | Female | Male | Lung - physiopathology | Humans | Asthma - epidemiology
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17. Chronic obstructive pulmonary disease: Definition and epidemiology
by Mannino, David M
Respiratory Care, ISSN 0020-1324, 2003, Volume 48, Issue 12, pp. 1185 - 1191
Chronic obstructive pulmonary disease (COPD) continues to cause a heavy health and economic burden in the United States and around the world. Some of the risk... 
Chronic obstructive pulmonary disease | COPD | Severity of Illness Index | Pulmonary Disease, Chronic Obstructive - diagnosis | United States - epidemiology | Prevalence | Humans | Middle Aged | Pulmonary Disease, Chronic Obstructive - classification | Terminology as Topic | Male | Survival Rate | Pulmonary Disease, Chronic Obstructive - epidemiology | Adult | Female | Aged
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18. Full Text Impact of donor lung pathogenic bacteria on patient outcomes in the immediate post‐transplant period
by Ahmad, Omar and Shafii, Alexis E and Mannino, David M and Choate, Radmila and Baz, Maher A
Transplant Infectious Disease, ISSN 1398-2273, 12/2018, Volume 20, Issue 6, pp. e12986 - n/a
Background Patient outcomes post‐lung transplant remain inferior to other types of solid organ transplantation. We investigated whether the presence of... 
acute kidney injury | lung transplantation | bacteria | mechanical ventilation | primary graft dysfunction | Lung - microbiology | Humans | Middle Aged | Male | Acute Lung Injury - epidemiology | Incidence | Anti-Bacterial Agents - therapeutic use | Graft Rejection - epidemiology | Allografts - microbiology | Time Factors | Adult | Female | Acute Lung Injury - drug therapy | Retrospective Studies | Graft Rejection - drug therapy | Mortality | Postoperative Period | Treatment Outcome | Graft Rejection - microbiology | Lung Transplantation - adverse effects | Bacteria - isolation & purification | Acute Lung Injury - microbiology | Tissue Donors - statistics & numerical data | Respiration, Artificial - statistics & numerical data | Aged | Heart | Medical research | Patient outcomes | Organ transplant recipients | Medicine, Experimental | Transplantation of organs, tissues, etc | Cystic fibrosis | Bacteria | Donation of organs, tissues, etc | Transplants & implants | Syngeneic grafts | Pulmonary arteries | Lung transplantation | Organs | Cultures | Population studies | Transplantation | Bronchiectasis | Regression analysis | Patients | Clinical outcomes | Pulmonary artery | Medical centres | Fibrosis | Ventilation | Smoking | Kidney transplantation
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19. Chronic obstructive pulmonary disease surveillance--United States, 1971-2000
by Mannino, David M and Homa, David M and Akinbami, Lara J and Ford, Earl S and Redd, Stephen C
Respiratory care, ISSN 0020-1324, 2002, Volume 47, Issue 10, pp. 1184 - 1199
Chronic obstructive pulmonary disease (COPD) includes chronic bronchitis and emphysema but has been defined recently as the physiologic finding of... 
Office Visits - statistics & numerical data | Pulmonary Disease, Chronic Obstructive - mortality | United States - epidemiology | Ambulatory Care Facilities - statistics & numerical data | Humans | Middle Aged | Hospitalization - statistics & numerical data | Male | Emergency Service, Hospital - statistics & numerical data | Pulmonary Disease, Chronic Obstructive - epidemiology | Activities of Daily Living | Pulmonary Disease, Chronic Obstructive - therapy | Adult | Female | Aged | Population Surveillance
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20. Full Text Exacerbation recovery patterns in newly diagnosed or maintenance treatment-naïve patients with COPD: Secondary analyses of TICARI 1 trial data
by Mannino, David M and Clerisme-Beaty, Emmanuelle M and Franceschina, Joanne and Ting, Naitee and Leidy, Nancy K
International Journal of COPD, ISSN 1176-9106, 05/2018, Volume 13, pp. 1515 - 1525
Little is known about the recovery patterns from acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in newly diagnosed or maintenance... 
Tiotropium | AECOPD | Acute exacerbation of chronic obstruc­tive pulmonary disease | Pulmonary function | Maintenance therapy | COPD Assessment Test | EXACT | Acute respiratory tract infection symptoms | Infection | Medical research | Care and treatment | Lung diseases, Obstructive | Analysis | Chronic diseases | Clinical trials | Medicine, Experimental | Health aspects | Patient compliance | acute exacerbation of chronic obstructive pulmonary disease (AECOPD) | acute respiratory tract infection symptoms | pulmonary function | maintenance therapy | tiotropium
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