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JOURNAL OF CELLULAR PHYSIOLOGY, ISSN 0021-9541, 09/2015, Volume 230, Issue 9, pp. 2067 - 2074
Cutaneous squamous cell carcinomas (SCCs) typically lack somatic oncogene-activating mutations and most of them contain p53 mutations. However, the presence of... 
SURVIVAL | MIGRATION | APOPTOSIS | INVASION | PHYSIOLOGY | GROWTH | PROLIFERATION | P63 | SUPPRESSION | EXPRESSION | P73 | CELL BIOLOGY | Binding | Squamous cell carcinoma | Cell survival | p53 Protein | AKT protein | Metastasis | Survival | Nuclear factor I | 1-Phosphatidylinositol 3-kinase | Metastases | Signaling | Detachment | Cell death | Skin diseases | Skin | Mutation | Lesions
Journal Article
Genes to Cells, ISSN 1356-9597, 06/2016, Volume 21, Issue 6, p. 648
  Y-box binding protein 1 (YBX-1 or YB-1) is an oncoprotein that promotes replicative immortality, tumor cell invasion and metastasis. The increase in the... 
Proteins | Rodents
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 7056 - 9
ARF role as tumor suppressor has been challenged in the last years by several findings of different groups ultimately showing that its functions can be... 
ADHESION | PROTEIN STABILITY | P14(ARF) | MULTIDISCIPLINARY SCIENCES | ALPHA | ARF TUMOR-SUPPRESSOR | DEFICIENT MICE | AUTOPHAGY | DELTA-NP63-ALPHA | KINASE-C PKC | MOTILITY | Cell proliferation | Phosphorylation | Protein kinase C | Threonine | Kinases | Cell spreading | Signal transduction | Hypotheses | Cell growth | Cell activation | Tumor suppressor genes | Anoikis | Focal adhesion kinase | Cell migration
Journal Article
Journal Article
Cell Cycle, ISSN 1538-4101, 08/2006, Volume 5, Issue 16, pp. 1816 - 1822
P63, a protein related to the tumor suppressor p53, is a transcription factor that plays an important role in epidermal differentiation and limb development.... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Ubiquitin | AIP4 | HECT domain | Itch | Protein degradation | Ubiquitin ligase | p63 | ubiquitin ligase | TRANSCRIPTIONAL ACTIVITY | INDUCED APOPTOSIS | DELTA-NP63-ALPHA | ubiquitin | CELL BIOLOGY | UBIQUITINATION | INHIBITION | MDM2 | TUMOR-SUPPRESSOR | P53 FAMILY | SAM DOMAIN | protein degradation | P63-ALPHA | Cyclin-Dependent Kinase Inhibitor p57 - genetics | Humans | Transcriptional Activation | Ubiquitin - metabolism | Foot Deformities, Congenital - genetics | Trans-Activators - chemistry | Promoter Regions, Genetic - genetics | DNA-Binding Proteins - metabolism | Lysosomes - metabolism | Transfection | Luciferases | Tumor Suppressor Proteins - chemistry | Tumor Suppressor Proteins - genetics | Trans-Activators - genetics | Lysine - metabolism | Proto-Oncogene Proteins c-mdm2 - metabolism | Genes, Reporter | Repressor Proteins - metabolism | Amino Acid Sequence | Tumor Suppressor Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Repressor Proteins - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Lysine - genetics | Hand Deformities, Congenital - genetics | Cell Line, Tumor | Protein Binding | Trans-Activators - metabolism | Transcription Factors | Mutation | Proteasome Endopeptidase Complex - metabolism | Lysine - chemistry | Ubiquitin-Protein Ligases - genetics
Journal Article
Cell Cycle, ISSN 1538-4101, 01/2005, Volume 4, Issue 1, pp. 183 - 190
Post-translational modification of proteins by the ubiquitin-like molecule SUMO-1 regulates their stability and activity with crucial implications for many... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Development | p63 | SUMO-1 | development | DNA-DAMAGE | HOMOLOG | IDENTIFICATION | P73 | FAMILY | CELL BIOLOGY | P53 STABILITY | GENE | SQUAMOUS-CELL CARCINOMA | MDM2
Journal Article
Cell Cycle, ISSN 1538-4101, 04/2009, Volume 8, Issue 8, pp. 1185 - 1195
Journal Article
Gene, 12/2017
ΔNp63α is finely and strictly regulated during embryogenesis and differentiation. ΔNp63α is the only p63 isoform degraded by the proteasome after Ubiquitin and... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2002, Volume 277, Issue 4, pp. 2674 - 2681
Genetic alteration of the p53 tumor suppressor gene, which monitors DNA damage and operates cell cycle checkpoints, is a major factor in the development of... 
LIMB | ACTIVATION | P19(ARF) | BIOCHEMISTRY & MOLECULAR BIOLOGY | SIGNALS | DEGRADATION | PROMOTER | P73 | FAMILY | P73-ALPHA
Journal Article
Journal Article
Cell Cycle, ISSN 1538-4101, 11/2009, Volume 8, Issue 21, pp. 3545 - 3551
The tumor suppressor p14ARF inhibits cell growth in response to oncogenic stress in a p53¬dependent and independent manner. However, new physiologic roles for... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2002, Volume 291, Issue 5, pp. 1138 - 1145
Journal Article