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SCIENTIFIC REPORTS, ISSN 2045-2322, 07/2019, Volume 9, Issue 1, pp. 1 - 7
Aneuploidy has been reported to occur at remarkably high levels in normal somatic tissues using Fluorescence In Situ Hybridization (FISH). Recently, these... 
MULTIDISCIPLINARY SCIENCES | NEURONS | SENESCENCE | PLOIDY | CYTOGENETICS | BRAIN | COPY-NUMBER VARIATION | Aneuploidy | Genomes | Hybridization | Fluorescence in situ hybridization
Journal Article
BRITISH JOURNAL OF CANCER, ISSN 0007-0920, 04/2019, Volume 120, Issue 7, pp. 746 - 753
BACKGROUND: Oncogenes promote the development of therapeutic targets against subsets of cancers. Only several hundred oncogenes have been identified, primarily... 
NELL2 | COMPLEX | GENE | RNA | ONCOLOGY | HALLMARK | CANCER | EXPRESSION | EZH2 | Cell survival | Transcription | Therapeutic applications | Invasiveness | Breast cancer | Genomes | Statistical methods | Gene expression | Heterogeneity | Breast carcinoma | Cell cycle | DNA methylation | Breast | Mutation | Methylation | Deoxyribonucleic acid--DNA | Tumors | Cancer
Journal Article
by Carbajo, Daniel and Magi, Shigeyuki and Itoh, Masayoshi and Kawaji, Hideya and Lassmann, Timo and Arner, Erik and Forrest, Alistair R. R and Carninci, Piero and Hayashizaki, Yoshihide and Daub, Carsten O and Okada-Hatakeyama, Mariko and Mar, Jessica C and Rehli, Michael and Baillie, J. Kenneth and de Hoon, Michiel J. L and Haberle, Vanja and Kulakovskiy, Ivan V and Lizio, Marina and Andersson, Robin and Mungall, Christopher J and Meehan, Terrence F and Schmeier, Sebastian and Bertin, Nicolas and Jørgensen, Mette and Dimont, Emmanuel and Schmidl, Christian and Schaefer, Ulf and Medvedeva, Yulia A and Plessy, Charles and Vitezic, Morana and Severin, Jessica and Semple, Colin A and Ishizu, Yuri and Francescatto, Margherita and Alam, Intikhab and Albanese, Davide and Altschuler, Gabriel M and Archer, John A. C and Arner, Peter and Babina, Magda and Baker, Sarah and Balwierz, Piotr J and Beckhouse, Anthony G and Pradhan-Bhatt, Swati and Blake, Judith A and Blumenthal, Antje and Bodega, Beatrice and Bonetti, Alessano and Briggs, James and Brombacher, Frank and Burroughs, A. Maxwell and Califano, Anea and Cannistraci, Carlo V and Chen, Yun and Chierici, Marco and Ciani, Yari and Clevers, Hans C and Dalla, Emiliano and Davis, Carrie A and Detmar, Michael and Diehl, Alexander D and Dohi, Taeko and bløs, Finn and Edge, Albert S. B and Edinger, Matthias and Ekwall, Karl and Endoh, Mitsuhiro and Enomoto, Hideki and Fagiolini, Michela and Fairbairn, Lynsey and Fang, Hai and Farach-Carson, Mary C and Faulkner, Geoffrey J and Favorov, Alexander V and Fisher, Malcolm E and Frith, Martin C and Fujita, Rie and Fukuda, Shiro and Furlanello, Cesare and Furuno, Masaaki and Furusawa, Jun-ichi and Geijtenbeek, Teunis B and Gibson, Anew and Gingeras, Thomas and Goldowitz, Daniel and Gough, Julian and Guhl, Sven and Guler, Reto and Gustincich, Stefano and Ha, Thomas J and Hamaguchi, Masahide and Hara, Mitsuko and Harbers, Matthias and Harshbarger, Jayson and Hasegawa, Akira and Hasegawa, Yuki and Hashimoto, Takehiro and Herlyn, Meenhard and Hitchens, Kelly J and Ho Sui, Shannan J and ... and FANTOM Consortium and FANTOM consortium
PLoS ONE, ISSN 1932-6203, 2015, Volume 10, Issue 12, pp. e0144176 - e0144176
Understanding how cells use complex transcriptional programs to alter their fate in response to specific stimuli is an important question in biology. For the... 
TRANSCRIPTION FACTORS | NETWORK | PRODUCTS | IREFINDEX | MULTIDISCIPLINARY SCIENCES | UPDATE | CELL-DIFFERENTIATION | PROTEIN-INTERACTION DATABASE | MOLECULAR INTERACTION DATABASE | DURATION | RESOURCE | Cell Cycle - genetics | ErbB Receptors - metabolism | Gene Expression - drug effects | Gene Expression Regulation - genetics | Humans | ErbB Receptors - genetics | Apoptosis - genetics | Gene Expression Profiling | Extracellular Signal-Regulated MAP Kinases - metabolism | Neuregulin-1 - pharmacology | Enzyme Activation - drug effects | Promoter Regions, Genetic - genetics | Tumor Suppressor Protein p53 - genetics | Focal Adhesions - genetics | Breast Neoplasms - genetics | MAP Kinase Signaling System - genetics | MCF-7 Cells | Cell Differentiation - drug effects | Cell Line, Tumor | Female | Cell Proliferation - drug effects | Epidermal Growth Factor - pharmacology | FHL2 protein | Regulators | Transcription | Ontology | Laboratories | p53 Protein | Genes | Biology | Activation | Genomes | Heregulin | Kinases | Data bases | Complexity | Consortia | Proteins | Signal transduction | Epidermal growth factor | Cell fate | Cell cycle | Life sciences | Bioinformatics | Medical research | ErbB protein | Extracellular signal-regulated kinase | MAP kinase | Data processing | Breast cancer | Trajectories | Preventive medicine | Metabolism | Gene expression | Promoters | Signaling | Acids | Cell death | Genetic engineering | Receptor mechanisms | Gene mapping | Stimuli | Cancer | Index Medicus
Journal Article
PLoS Genetics, ISSN 1553-7390, 08/2015, Volume 11, Issue 8
  An analysis of gene expression variability can provide an insightful window into how regulatory control is distributed across the transcriptome. In a single... 
Studies | DNA methylation | Annotations | Gene expression | Telomerase | Stem cells
Journal Article
PeerJ, ISSN 2167-8359, 2017, Volume 2017, Issue 5, pp. e3334 - e3334
Identifying the pathways that control a cellular phenotype is the first step to building a mechanistic model. Recent examples in developmental biology, cancer... 
Cellular heterogeneity | Gene expression variability | Transcriptional regulation | Functional genomics | Single cell analysis | Bioinfor-matics | Phenotype | Genetic variation | Analysis | Models | Gene expression | Genetic regulation | Methods | Studies | Statistical analysis | Acids | Transcription | Gene regulation | Genomics | Stem cells | Biology | Metastasis | Cancer | Bioinformatics
Journal Article
by Forrest, Alistair R. R and Kawaji, Hideya and Rehli, Michael and Baillie, J. Kenneth and de Hoon, Michiel J. L and Haberle, Vanja and Lassmann, Timo and Kulakovskiy, Ivan V and Lizio, Marina and Itoh, Masayoshi and Andersson, Robin and Mungall, Christopher J and Meehan, Terrence F and Schmeier, Sebastian and Bertin, Nicolas and Jørgensen, Mette and Dimont, Emmanuel and Arner, Erik and Schmidl, Christian and Schaefer, Ulf and Medvedeva, Yulia A and Plessy, Charles and Vitezic, Morana and Severin, Jessica and Semple, Colin A and Ishizu, Yuri and Young, Robert S and Francescatto, Margherita and Alam, Intikhab and Albanese, Davide and Altschuler, Gabriel M and Arakawa, Takahiro and Archer, John A. C and Arner, Peter and Babina, Magda and Rennie, Sarah and Balwierz, Piotr J and Beckhouse, Anthony G and Pradhan-Bhatt, Swati and Blake, Judith A and Blumenthal, Antje and Bodega, Beatrice and Bonetti, Alessano and Briggs, James and Brombacher, Frank and Burroughs, A. Maxwell and Califano, Anea and Cannistraci, Carlo V and Carbajo, Daniel and Chen, Yun and Chierici, Marco and Ciani, Yari and Clevers, Hans C and Dalla, Emiliano and Davis, Carrie A and Detmar, Michael and Diehl, Alexander D and Dohi, Taeko and bløs, Finn and Edge, Albert S. B and Edinger, Matthias and Ekwall, Karl and Endoh, Mitsuhiro and Enomoto, Hideki and Fagiolini, Michela and Fairbairn, Lynsey and Fang, Hai and Farach-Carson, Mary C and Faulkner, Geoffrey J and Favorov, Alexander V and Fisher, Malcolm E and Frith, Martin C and Fujita, Rie and Fukuda, Shiro and Furlanello, Cesare and Furuno, Masaaki and Furusawa, Jun-ichi and Geijtenbeek, Teunis B and Gibson, Anew P and Gingeras, Thomas and Goldowitz, Daniel and Gough, Julian and Guhl, Sven and Guler, Reto and Gustincich, Stefano and Ha, Thomas J and Hamaguchi, Masahide and Hara, Mitsuko and Harbers, Matthias and Harshbarger, Jayson and Hasegawa, Akira and Hasegawa, Yuki and Hashimoto, Takehiro and Herlyn, Meenhard and Hitchens, Kelly J and Ho Sui, Shannan J and Hofmann, Oliver M and Hoof, Ilka and Hori, Fumi and Huminiecki, Lukasz and ... and FANTOM Consortium and RIKEN PMI CLST DGT and FANTOM Consortium and the RIKEN PMI and CLST (DGT) and The FANTOM Consortium and the RIKEN PMI and CLST (DGT)
Nature, ISSN 0028-0836, 2014, Volume 507, Issue 7493, pp. 462 - +
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2011, Volume 108, Issue 36, pp. 14902 - 14907
Epstein-Barr virus nuclear antigen 2 (EBNA2) regulation of transcription through the cell transcription factor RBPJ is essential for resting B-lymphocyte (RBL)... 
T lymphocytes | Up regulation | Chromatin | B lymphocytes | DNA | Nucleosomes | Gene expression regulation | Epstein Barr virus infections | Human herpesvirus 4 | Binding sites | Development | Lymphoma | Leukemia | Notch | leukemia | development | SIGNAL-BINDING-PROTEIN | CIS-ELEMENT | MULTIDISCIPLINARY SCIENCES | lymphoma | C-MYC | NUCLEAR ANTIGEN-2 | FATE | GENOME | LONG-RANGE INTERACTION | GENE | PROMOTER | J-KAPPA | Cell Proliferation | Herpesvirus 4, Human - genetics | Proto-Oncogene Proteins c-ets - genetics | Genome, Viral - genetics | Humans | Transcription Factor RelA - genetics | Viral Proteins - metabolism | Trans-Activators - genetics | B-Lymphocytes - virology | Epstein-Barr Virus Infections - genetics | Core Binding Factor alpha Subunits - metabolism | Transcription, Genetic | Proto-Oncogene Proteins c-ets - metabolism | Epstein-Barr Virus Nuclear Antigens - metabolism | Immunoglobulin J Recombination Signal Sequence-Binding Protein - genetics | B-Lymphocytes - metabolism | Proto-Oncogene Proteins - metabolism | Immunoglobulin J Recombination Signal Sequence-Binding Protein - metabolism | Epstein-Barr Virus Nuclear Antigens - genetics | Response Elements | Nucleosomes - metabolism | Viral Proteins - genetics | Nucleosomes - genetics | Proto-Oncogene Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | Core Binding Factor alpha Subunits - genetics | Transcription Factor RelA - metabolism | Cell Line, Tumor | Trans-Activators - metabolism | Proto-Oncogene Proteins c-myc - genetics | Herpesvirus 4, Human - metabolism | Epstein-Barr Virus Infections - metabolism | Physiological aspects | Transcription factors | Epstein-Barr virus | Genetic aspects | Lymphocytes | Health aspects | Cell growth | Deoxyribonucleic acid--DNA | Index Medicus | ETS protein | Lymphoblasts | Introns | Data processing | Genomes | Myc protein | Promoters | Early B-cell factor | Infection | Enhancers | PU.1 protein | Lymphocytes B | Fluorescence in situ hybridization | RelA protein | Conformation | Biological Sciences
Journal Article