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Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 07/2019, Volume 10, Issue 1, pp. 3287 - 16
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2015, Volume 112, Issue 49, pp. 15160 - 15165
The Wee1 cell cycle checkpoint kinase prevents premature mitotic entry by inhibiting cyclin-dependent kinases. Chemical inhibitors of Wee1 are currently being... 
Checkpoint | Polyploidy | AZD-1775 | Cell cycle | MK-1775 | Cell Cycle Proteins - antagonists & inhibitors | Haploidy | Humans | Nuclear Proteins - antagonists & inhibitors | G1 Phase - genetics | S Phase - genetics | Protein-Tyrosine Kinases - antagonists & inhibitors | checkpoint | Biological Sciences | polyploidy | cell cycle
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2010, Volume 40, Issue 1, pp. 34 - 49
Following genotoxic stress, cells activate a complex kinase-based signaling network to arrest the cell cycle and initiate DNA repair. p53-defective tumor cells... 
CANCER-CELLS | CHK1 | P38 | AU-RICH ELEMENTS | MEDIATE ACTIVATION | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MAPKAP KINASE-2 | NUCLEAR EXPORT | ONCOGENE-INDUCED SENESCENCE | KINASE ACTIVATION | CELL BIOLOGY | Protein Kinases - metabolism | Cell Cycle - genetics | Phosphorylation | Antibiotics, Antineoplastic - pharmacology | RNA Processing, Post-Transcriptional - radiation effects | Mitosis | Humans | Intracellular Signaling Peptides and Proteins - metabolism | RNA Stability - drug effects | RNA, Messenger - metabolism | Cell Nucleus - enzymology | Transfection | Ultraviolet Rays | RNA Interference | Time Factors | Cell Cycle Proteins - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | Active Transport, Cell Nucleus | Head and Neck Neoplasms - enzymology | cdc25 Phosphatases - metabolism | 3' Untranslated Regions | Nuclear Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Cytoplasm - enzymology | Signal Transduction | RNA Processing, Post-Transcriptional - drug effects | Cell Cycle - radiation effects | Protein-Serine-Threonine Kinases - genetics | Heterogeneous-Nuclear Ribonucleoproteins - metabolism | Feedback, Physiological | DNA Repair | Checkpoint Kinase 1 | Head and Neck Neoplasms - genetics | DNA Damage | HeLa Cells | Cell Cycle - drug effects | RNA Stability - radiation effects | Doxorubicin - pharmacology | Exoribonucleases - metabolism | RNA-Binding Proteins - metabolism | Messenger RNA | Oncology, Experimental | DNA | Genetics | Automated teller machines | Research | Universities and colleges | Tumor proteins | Gene expression | Cancer | Tumors
Journal Article
Plos one, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, pp. e0165385 - e0165385
Journal Article