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Analytical Chemistry, ISSN 0003-2700, 03/2016, Volume 88, Issue 6, pp. 3317 - 3323
Dereplication represents a key step for rapidly identifying known secondary metabolites in complex biological matrices. In this context, liquid-chromatography... 
CHEMISTRY, ANALYTICAL | METABOLITES | DATABASE | SUBEROYLANILIDE HYDROXAMIC ACID | PATHWAY | ANNOTATION | MASS | SCHWEINFURTHIN | PROLIFERATION | IDENTIFICATION | DISCOVERY | Biological Products - chemistry | Chromatography, Liquid - methods | Tandem Mass Spectrometry - methods | Computer Simulation
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e64006
Natural products (NPs) are an attractive source of chemical diversity for small-molecule drug discovery. Several challenges nevertheless persist with respect... 
ULTRA-HIGH PRESSURE | INHIBITION | LIQUID-CHROMATOGRAPHY | ANGIOGENESIS | MULTIDISCIPLINARY SCIENCES | DRUG DISCOVERY | ISOFLAVONE | GENISTEIN | IDENTIFICATION | STRUCTURE ELUCIDATION | MASS-SPECTROMETRY | Plant Extracts - chemistry | Blood Vessels - growth & development | Plant Extracts - pharmacology | Biological Products - pharmacology | Leukocytes - immunology | Mass Spectrometry | Inhibitory Concentration 50 | Nuclear Magnetic Resonance, Biomolecular | Microfluidic Analytical Techniques | Plants, Medicinal - chemistry | Animals, Genetically Modified | Anti-Inflammatory Agents - pharmacology | Fabaceae - chemistry | Angiogenesis Inhibitors - pharmacology | Plant Extracts - isolation & purification | Zebrafish | Biological Assay - methods | Drug Discovery | Biological Products - isolation & purification | Cell Movement - drug effects | Biological Products - chemistry | Animals | Anti-Inflammatory Agents - chemistry | Chemical Fractionation | Blood Vessels - drug effects | Leukocytes - drug effects | Angiogenesis Inhibitors - chemistry | Medicinal plants | Medicine, Herbal | Drug discovery | Medicine, Botanic | Analytical methods | Nuclear magnetic resonance--NMR | Laboratories | Identification methods | Identification | Kinases | Optimization | Angiogenesis | Biological effects | Biomedical materials | Metabolites | Mathematical analysis | Bioactive compounds | Pharmaceutical sciences | Isoflavones | Fractionation | Bioassay | Bioassays | Inflammation | Biological assays | Medical screening | Anti-inflammatory agents | Biological activity | Chromatography | Screening | Natural products | Pharmacy | Scientific imaging | In vivo methods and tests | Mass spectrometry | Nuclear magnetic resonance | NMR
Journal Article
Journal Article
Journal of Chromatography A, ISSN 0021-9673, 08/2019, Volume 1598, pp. 85 - 91
Semi-preparative HPLC is one of the main techniques used for the purification of natural products (NPs). Generally, the sample has to be solubilized in organic... 
Dry load injection | Semi-preparative HPLC | Natural products | Resolution | Plant extracts | FAST LIQUID-CHROMATOGRAPHY | CHEMISTRY, ANALYTICAL | SMALL-PARTICLE | BIOCHEMICAL RESEARCH METHODS | PHARMACEUTICAL ANALYSIS | HPLC | EXTRACT
Journal Article
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 11/2012, Volume 2012, Issue 31, pp. 6197 - 6203
The fungus Coniothyrium cereale was isolated from the Baltic Sea alga Enteromorpha sp. Upon cultivation in saline medium, C. cereale produced the structurally... 
Heterocycles | Polyketides | Inhibitors | NMR spectroscopy | Natural products | CONFIGURATION | HUMAN-LEUKOCYTE ELASTASE | CHEMISTRY, ORGANIC | C-4 | HERQUEINONE | A-C | FERMENTATION | DIHYDROHERQUEINONE MONOMETHYL ETHER | DERIVATIVES | ALKALOIDS | Fungi | Metabolites | Proteases | Analysis | Nuclear magnetic resonance spectroscopy | Universities and colleges | Mass spectrometry
Journal Article
Journal Article
Phytochemical Analysis, ISSN 0958-0344, 03/2017, Volume 28, Issue 2, p. 87
[alpha]-Glucosidase inhibitors form an essential basis for the development of novel drugs in diabetes type 2 treatment. Searching for [alpha]-glucosidase... 
Enzymes | Biological products | Diastereomers | Hydrolases | Diabetes | Medical screening | High performance liquid chromatography
Journal Article
Phytomedicine, ISSN 0944-7113, 11/2019, Volume 64, p. 153075
Obesity is one of the major health problems worldwide. The induction of brown adipocyte formation and activity represents a promising therapeutic option by... 
UCP1 | Obesity | Daidzein | Puerarin | Genistein | Asian herbs | CHEMISTRY, MEDICINAL | RADIX | RATS | IDENTIFICATION | DECOCTION | PLANT SCIENCES | INTEGRATIVE & COMPLEMENTARY MEDICINE | GENE-EXPRESSION | ISOFLAVONE | PHARMACOLOGY & PHARMACY | MICE | WEIGHT | ADIPOSE-TISSUE
Journal Article