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by Nalls, Mike A and Pankratz, Nathan and Lill, Christina M and Do, Chuong B and Hernandez, Dena G and Saad, Mohamad and DeStefano, Anita L and Kara, Eleanna and Bras, Jose and Sharma, Manu and Schulte, Claudia and Keller, Margaux F and Arepalli, Sampath and Letson, Christopher and Edsall, Connor and Stefansson, Hreinn and Liu, Xinmin and Pliner, Hannah and Lee, Joseph H and Cheng, Rong and Ikram, M. Arfan and Ioannidis, John P. A and Hadjigeorgiou, Georgios M and Bis, Joshua C and Martinez, Maria and Perlmutter, Joel S and Goate, Alison and Marder, Karen and Fiske, Brian and Sutherland, Margaret and Xiromerisiou, Georgia and Myers, Richard H and Clark, Lorraine N and Stefansson, Kari and Hardy, John A and Heutink, Peter and Chen, Honglei and Wood, Nicholas W and Houlden, Henry and Payami, Haydeh and Brice, Alexis and Scott, William K and Gasser, Thomas and Bertram, Lars and Eriksson, Nicholas and Foroud, Tatiana and Singleton, Anew B and Plagnol, Vincent and Sheerin, Una-Marie and Simón-Sánchez, Javier and Lesage, Suzanne and Sveinbjörnsdóttir, Sigurlaug and Barker, Roger and Ben-Shlomo, Yoav and Berendse, Henk W and Berg, Daniela and Bhatia, Kailash and de Bie, Rob M. A and Biffi, Alessano and Bloem, Bas and Bochdanovits, Zoltan and Bonin, Michael and Bras, Jose M and Brockmann, Kathrin and Brooks, Janet and Burn, David J and Charlesworth, Gavin and Chinnery, Patrick F and Chong, Sean and Clarke, Carl E and Cookson, Mark R and Cooper, J. Mark and Corvol, Jean Christophe and Counsell, Carl and Damier, Philippe and Dartigues, Jean-François and Deloukas, Panos and Deuschl, Günther and Dexter, David T and van Dijk, Karin D and Dillman, Allissa and Durif, Frank and Dürr, Alexana and Edkins, Sarah and Evans, Jonathan R and Foltynie, Thomas and Dong, Jing and Gardner, Michelle and Gibbs, J. Raphael and Gray, Emma and Guerreiro, Rita and Harris, Clare and van Hilten, Jacobus J and Hofman, Albert and Hollenbeck, Albert and Holton, Janice and Hu, Michele and Huang, Xuemei and Wurster, Isabel and Mätzler, Walter and ... and GenePD and IPDG and Ashkenazi Jewish Dataset Investiga and 23AndMe and NABEC and HIHG and Greek Parkinson's Dis Consortium and GParkinson's Study Grp PSG Parkins and NGRC and Alzheimer Genetic Analysis Gr and CHARGE and UKBEC and Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI) and Hussman Institute of Human Genomics (HIHG) and 23andMe and Greek Parkinson's Disease Consortium and International Parkinson's Disease Genomics Consortium (IPDGC) and Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE) and United Kingdom Brain Expression Consortium (UKBEC) and NeuroGenetics Research Consortium (NGRC) and Ashkenazi Jewish Dataset Investigator and North American Brain Expression Consortium (NABEC) and Alzheimer Genetic Analysis Group and The Ashkenazi Jewish Dataset Investigator
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 9, pp. 989 - +
Journal Article
Clinical Genetics, ISSN 0009-9163, 07/2019, Volume 96, Issue 1, pp. 28 - 34
Rates of genetic testing in Huntington disease (HD) are lower than was predicted before direct DNA testing became available. Clinicians often do not have... 
genetic testing | at risk | Huntington disease | GENETICS & HEREDITY | RISK | EXPERIENCE | ATTITUDES | Huntington's chorea | Medical tests | Diagnosis | Clinical trials | Huntingtin | Huntington's disease | Genetic screening | Deoxyribonucleic acid--DNA
Journal Article
Current Neurology and Neuroscience Reports, ISSN 1528-4042, 09/2010, Volume 10, Issue 5, pp. 336 - 337
Journal Article
Neuron, ISSN 0896-6273, 02/2013, Volume 77, Issue 3, pp. 425 - 439
Recent genome-wide association studies have linked common variants in the human genome to Parkinson@s disease (PD) risk. Here we show that the consequences of... 
LOCALIZATION | RETROMER | TRANSPORT | COMPLEX | KINASE | GENE-EXPRESSION | TRAFFICKING | ALPHA | NEURODEGENERATION | MICE | NEUROSCIENCES | rab5 GTP-Binding Proteins - genetics | Immunoprecipitation | Humans | Middle Aged | Cerebral Cortex - pathology | Male | Tubulin - genetics | rab GTP-Binding Proteins - genetics | Green Fluorescent Proteins - genetics | Statistics as Topic | Vesicle-Associated Membrane Protein 2 - genetics | Cerebral Cortex - cytology | Tyrosine 3-Monooxygenase | rab5 GTP-Binding Proteins - metabolism | Tubulin - metabolism | Transfection | Aged, 80 and over | Female | Neurons - metabolism | Parkinson Disease - metabolism | Protein-Serine-Threonine Kinases - metabolism | Animals, Newborn | Synaptosomal-Associated Protein 25 - genetics | rab GTP-Binding Proteins - metabolism | Genetic Predisposition to Disease | Genome-Wide Association Study | Parkinson Disease - pathology | Animals, Genetically Modified | Drosophila | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Rats | Parkinson Disease - genetics | Mutation - genetics | Rats, Sprague-Dawley | Protein Transport - genetics | Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 | Animals | Polymorphism, Single Nucleotide - genetics | Aged | Mice | Synaptosomal-Associated Protein 25 - metabolism | Vesicle-Associated Membrane Protein 2 - metabolism | Parkinson's disease | Neurons | Genomics | Risk factors | Brain | Laboratories | Parkinsons disease | Kinases | Gene expression | Experiments | Defects | Proteins | Pathology | Insects | Neurodegeneration | Gene loci | Mutation
Journal Article
by Reilmann, Ralf and McGarry, Andrew and Grachev, Igor D and Savola, Juha-Matti and Borowsky, Beth and Eyal, Eli and Gross, Nicholas and Langbehn, Douglas and Schubert, Robin and Wickenberg, Anna Teige and Papapetropoulos, Spyros and Hayden, Michael and Squitieri, Ferdinando and Kieburtz, Karl and Landwehrmeyer, G Bernhard and Agarwal, Pinky and Anderson, Karen E and Aziz, Nasir A and Azulay, Jean-Phillippe and Bachoud-Levi, Anne C and Barker, Roger and Bebak, Agnieszka and Beuth, Markus and Biglan, Kevin and Blin, Stephanie and Bohlen, Stefan and Bonelli, Raphael and Caldwell, Sue and Calvas, Fabienne and Carlos, Jonielyn and Castagliuolo, Simona and Chong, Terrence and Chua, Phyllis and Coleman, Allison and Corey-Bloom, Jody and Cousins, Rebecca and Craufurd, David and Davison, Jill and Decorte, Eric and De Michele, Giuseppe and Dornhege, Laura and Feigin, Andrew and Gallehawk, Stephanie and Gauteul, Pascale and Gonzales, Carey and Griffith, Jane and Gustov, Alexander and Guttman, Mark and Heim, Beatrix and Heller, Hope and Hjermind, Lena and Illarioshkin, Sergey and Ivanko, Larry and Jaynes, Jessica and Jenckes, Mollie and Kaminski, Barbara and Kampstra, Anne and Konkel, Agnieszka and Kopishinskaya, Svetlana and Krystkowiak, Pierre and Komati, Suresh K and Kwako, Alexander and Lakoning, Stefan and Latipova, Guzal and Leavitt, Blair and Loy, Clement and MacFarlane, Cheryl and Madsen, Louise and Marder, Karen and Mason, Sarah and Mendis, Tilak and Mendis, Neila and Nemeth, Andrea and Nevitt, Louise and Norris, Virginia and O'Neill, Christine and Olivier, Audrey and Orth, Michael and Owens, Ashley and Panegyres, Peter and Perlman, Susan and Preston, Joy and Priller, Josef and Puch, Alicja and Quarrell, Oliver and Ragosta, Domenica and Rialland, Amandine and Rickards, Hugh and Romoli, Anna M and Ross, Christopher and Rosser, Anne and Rudzinska, Monika and Russo, Cinzina V and Saft, Carsten and Segro, Victoria and Seppi, Klaus and Shannon, Barbara and Shprecher, David and Simonin, Clemence and Skitt, Zara and ... and European Huntingtons Dis Network and Huntington Study Grp Investigator and European Huntington's Disease Network and Huntington Study Group investigators
The Lancet Neurology, ISSN 1474-4422, 02/2019, Volume 18, Issue 2, pp. 165 - 176
Previous trials have shown that pridopidine might reduce motor impairment in patients with Huntington's disease. The aim of this study was to ascertain whether... 
OUTCOME MEASURES | CHOREA | MOBILITY | PERFORMANCE | ACR16 | RATING-SCALE | STABILIZER | PREMANIFEST | CLINICAL NEUROLOGY | Analysis | High-definition television | Huntingtons disease | Caregivers | Headache | Pneumonia | Huntingtin | Clinical trials | Nervous system | Rhinopharyngitis | Suicide | Guanine | Sleep disorders | Vomiting | Placebos | Cytosine | Anxiety | Safety | Drug dosages | Dopamine | Adenine | Diarrhea | Nausea | Huntington's disease | Patients | Studies | Poisoning
Journal Article
Journal of Huntington's Disease, ISSN 1879-6397, 01/2019, Volume 8, Issue 4, p. 435
Background: There is limited understanding of the feasibility of conducting long-term research among undiagnosed (pre-symptomatic) adults at risk to develop... 
Polyglutamine | Mental disorders | Withdrawal | Feasibility studies | Trinucleotide repeats | Mental depression | Suicide | Huntington's disease | Emotions | Genetic screening | Confidentiality | Suicides & suicide attempts | Safety
Journal Article
Current Neurology and Neuroscience Reports, ISSN 1528-4042, 2/2017, Volume 17, Issue 2, pp. 1 - 9
Understanding the overall progression of neurodegenerative diseases is critical to the timing of therapeutic interventions and design of effective clinical... 
Mixed effect models | Neurology | Missing data | Neurosciences | Medicine & Public Health | Longitudinal study | Time-varying effects | Generalized estimating equations
Journal Article
Journal Article