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Revista do Instituto de Medicina Tropical de Sao Paulo, ISSN 0036-4665, 2018, Volume 60
ABSTRACT In 2012, the first-generation protease inhibitors telaprevir (TVR) and boceprevir (BOC) were introduced in the Brazilian health system for treatment... 
High cost medicines | Chronic hepatitis C treatment | Protease inhibitors | Real life studies
Journal Article
REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO, ISSN 0036-4665, 2018, Volume 60, p. e29
In 2012, the first-generation protease inhibitors telaprevir (TVR) and boceprevir (BOC) were introduced in the Brazilian health system for treatment of chronic... 
High cost medicines | Protease inhibitors | Real life studies | SOFOSBUVIR | TREATMENT-EXPERIENCED PATIENTS | Chronic hepatitis C treatment | TRIPLE THERAPY | INFECTION | COHORT | VIROLOGICAL RESPONSE | TROPICAL MEDICINE
Journal Article
Research in Social and Administrative Pharmacy, ISSN 1551-7411, 2019
Background: In Brazil, the sofosbuvir-based therapy was introduced in the public health system (SUS) in 2015 to treat Chronic Hepatitis C (CHC). This drug and... 
Sofosbuvir-based therapy | Chronic hepatitis C | Clinical pharmacist | Real-life results
Journal Article
Revista do Instituto de Medicina Tropical de São Paulo, ISSN 1678-9946, 06/2018, Volume 60
ABSTRACT In 2012, the first-generation protease inhibitors telaprevir (TVR) and boceprevir (BOC) were introduced in the Brazilian health system for treatment... 
TROPICAL MEDICINE
Journal Article
Value in Health Regional Issues, ISSN 2212-1099, 12/2012, Volume 1, Issue 2, pp. 129 - 135
Hepatitis C therapy in Brazil is expensive due to the cost of antiviral drugs and demands on medical resources. The objective of this study was to estimate the... 
hepatitis C treatment | interferon | direct cost | hepatitis C | Interferon | Hepatitis C | Hepatitis C treatment | Direct cost
Journal Article
Brazilian Journal of Pharmaceutical Sciences, ISSN 1984-8250, 04/2012, Volume 48, Issue 2, pp. 193 - 201
This study aimed to evaluate the rate of sustained virological response (SVR) and the clinical and treatment characteristics of patients with chronic hepatitis... 
Hepatitis C chronic | Interferon alfa-2b | Interferon alfa-2a | Effectiveness | Hepatitis C | DESIGN | VIRUS-INFECTION | RATIONALE | COMBINATION THERAPY | GENOTYPE-1 | NONRESPONDERS | TRIAL | 40 KDA | INTERFERON-ALPHA-2B PLUS RIBAVIRIN | Hepatitis C Chronic | PHARMACOLOGY & PHARMACY | QUALITY-OF-LIFE | Hepatite C | Interferona alfa-2a | Hepatite C Crônica | Efetividade | Interferona alfa-2b
Journal Article
Brazilian Journal of Pharmaceutical Sciences, ISSN 2175-9790, 04/2014, Volume 50, Issue 2, pp. 345 - 352
Brazilian Guidelines to HCV treatment (2007) recommended that the first choice treatment for patients with chronic hepatitis C (CHC) and genotype 2 or 3 is... 
PHARMACOLOGY & PHARMACY
Journal Article
Brazilian Journal of Pharmaceutical Sciences, ISSN 2175-9790, 06/2012, Volume 48, Issue 2, pp. 193 - 201
This study aimed to evaluate the rate of sustained virological response (SVR) and the clinical and treatment characteristics of patients with chronic hepatitis... 
PHARMACOLOGY & PHARMACY
Journal Article
MEDISAN, ISSN 1029-3019, 10/2016, pp. 2224 - 2229
Se realizó un estudio descriptivo, prospectivo y transversal de 25 pacientes con coinfección por el virus de la hepatitis C y el de la inmunodeficiencia... 
MEDICINE, GENERAL & INTERNAL
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, p. e81194
The identification of germline variants predisposing to hereditary nonpolyposis colorectal cancer (HNPCC) is crucial for clinical management of carriers, but... 
COLON-CANCER | LYNCH-SYNDROME | GENOMIC REARRANGEMENTS | MICROSATELLITE INSTABILITY | GERMLINE EPIMUTATION | MULTIDISCIPLINARY SCIENCES | MSH2 MISSENSE | FUNCTIONAL-ANALYSIS | MISMATCH REPAIR DEFICIENCY | ADENOMATOUS POLYPOSIS | TUMOR CHARACTERISTICS | Antigens, Neoplasm - genetics | MutL Protein Homolog 1 | Promoter Regions, Genetic | Cell Adhesion Molecules - genetics | Genetic Testing | Alternative Splicing | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | Humans | Gene Expression Regulation, Neoplastic | MutS Homolog 2 Protein - genetics | DNA Mismatch Repair - genetics | DNA-Binding Proteins - genetics | Epithelial Cell Adhesion Molecule | DNA Methylation | Algorithms | Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis | Adaptor Proteins, Signal Transducing - genetics | Alleles | Germ-Line Mutation | Nuclear Proteins - genetics | Analysis | Genes | Colorectal cancer | Genetic aspects | Methylation | Gene expression | Genetic screening | Genomics | Colorectal carcinoma | Microsatellite instability | Multivariate analysis | Defects | Cell adhesion & migration | MMR protein | Mismatch repair | DNA methylation | Aging | Microsatellites | Stability | Patients | Adenomatous polyposis coli | Medicine | Pathology | Screening | Pharmacy | Gene rearrangement | Diagnostic systems | Mutation | Cancer | Tumors
Journal Article
Human Mutation, ISSN 1059-7794, 01/2017, Volume 38, Issue 1, pp. 64 - 77
Journal Article