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British Journal of Pharmacology, ISSN 0007-1188, 03/2015, Volume 172, Issue 5, p. 1305
  Background and Purpose This study aimed to address the questions of whether [Delta]9-tetrahydrocannabivarin (THCV) can (i) enhance activation of 5-HT1A... 
Psychotropic drugs | Rodents
Journal Article
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 11/2003, Volume 163, Issue 3, pp. 463 - 468
Diacylglycerol (DAG) lipase activity is required for axonal growth during development and for retrograde synaptic signaling at mature synapses. This enzyme... 
COS cells | Enzymes | Brain | Receptors | Neurons | Purkinje cells | Antibodies | Reports | Fatty acids | Endocannabinoids | Cells | Axonal growth | Diacylglycerol lipase | CB1 receptor | Synaptic plasticity | Anandamide | PURKINJE-CELLS | SYSTEM | 2-ARACHIDONOYLGLYCEROL | ENDOGENOUS CANNABINOIDS | RELEASE | IDENTIFICATION | CELL BIOLOGY | axonal growth | RETROGRADE INHIBITION | ANIMAL-MODEL | synaptic plasticity | RECEPTORS | diacylglycerol lipase | anandamide | Cannabinoid Receptor Modulators - metabolism | Brain - embryology | Humans | Neurites - enzymology | DNA, Complementary - genetics | Brain - enzymology | Molecular Sequence Data | Arachidonic Acids - biosynthesis | Presynaptic Terminals - enzymology | Time Factors | Cloning, Molecular | Lipoprotein Lipase - isolation & purification | Cell Differentiation - physiology | Neurites - drug effects | DNA, Complementary - analysis | Brain - cytology | Lipoprotein Lipase - genetics | Enzyme Inhibitors - pharmacology | Rats | Glycerides - biosynthesis | Protein Structure, Tertiary - genetics | Signal Transduction - genetics | Sequence Homology, Nucleic Acid | Synaptic Membranes - enzymology | Sequence Homology, Amino Acid | Animals | Growth Substances - pharmacology | Dendrites - enzymology | Mice | COS Cells | Lipase | Research | 2-arachidonylglycerol | Report | diacylglycerol lipase; CB1 receptor; anandamide; axonal growth; synaptic plasticity
Journal Article
Science, ISSN 0036-8075, 10/2003, Volume 302, Issue 5642, pp. 84 - 88
Abnormally high spiking activity can damage neurons. Signaling systems to protect neurons from the consequences of abnormal discharge activity have been... 
Brain | Receptors | Neuroscience | Messenger RNA | Neurons | Forebrain | Research Articles | Endocannabinoids | Genotypes | Hippocampus | Seizures | NERVOUS-SYSTEM | ENDOCANNABINOIDS | GLUTAMATE | MULTIDISCIPLINARY SCIENCES | ANANDAMIDE | SEIZURE | ACUTE NEURONAL INJURY | MICE | RAT-BRAIN | NEUROPROTECTION | N-ACYLETHANOLAMINE PHOSPHOLIPIDS | Brain-Derived Neurotrophic Factor - genetics | Receptors, Drug - genetics | gamma-Aminobutyric Acid - metabolism | Furans - pharmacology | Epilepsy - metabolism | Male | Epilepsy - physiopathology | Hippocampus - drug effects | Neuroprotective Agents - metabolism | Prosencephalon - drug effects | Brain - metabolism | Polyunsaturated Alkamides | Arachidonic Acids - metabolism | Piperidines - pharmacology | Excitatory Postsynaptic Potentials | Neurons - physiology | Brain-Derived Neurotrophic Factor - metabolism | Neurons - metabolism | Prosencephalon - metabolism | Neurons - drug effects | Cannabinoids - metabolism | Pyrazoles - pharmacology | Signal Transduction | Kainic Acid - pharmacology | Mice, Inbred C57BL | Mice, Transgenic | Excitatory Amino Acid Agonists - pharmacology | Glycerides - metabolism | Arachidonic Acids - pharmacology | Receptors, Drug - metabolism | Mice, Knockout | Brain - drug effects | Gene Expression Regulation - drug effects | Hippocampus - metabolism | Animals | Receptors, Cannabinoid | Glutamic Acid - metabolism | Mice | Genes, Immediate-Early | Mutation | In Vitro Techniques | Receptors, Drug - antagonists & inhibitors | Mitogen-Activated Protein Kinases - metabolism | Physiological aspects | Nervous system | Cannabinoids | Research | Convulsions & seizures
Journal Article
Journal Article
Journal Article
Journal Article
Handbook of Experimental Pharmacology, ISSN 0171-2004, 09/2015, Volume 231, pp. 39 - 58
Since the discovery of the two cannabinoid receptors, CB(1) and CB(2), several molecules, commonly defined as endocannabinoids, able to bind to and... 
Degradation | Biosynthesis | 2-arachidonoylglycerol | Endocannabinoids | Uptake | Anandamide | Amidohydrolases - metabolism | Hydrolysis | Polyunsaturated Alkamides | Monoacylglycerol Lipases - metabolism | Animals | Humans | Endocannabinoids - biosynthesis | Glycerides - biosynthesis | Arachidonic Acids - biosynthesis
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 2015, Volume 172, Issue 5, pp. 1305 - 1318
Journal Article
Journal Article
Pharmacological Research, ISSN 1043-6618, 11/2016, Volume 113, pp. 199 - 208
Historical and scientific evidence suggests that use has immunomodulatory and anti-inflammatory effects. We have here investigated the effect of the... 
Phytocannabinoids | Cannabis | Inflammation | Cannabinoid receptors | Transient receptor potential (TRP) channels
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2015, Volume 172, Issue 5, pp. 1305 - 1318
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2015, Volume 172, Issue 5, pp. 1305 - 1318
Background and Purpose This study aimed to address the questions of whether Delta super(9)-tetrahydrocannabivarin (THCV) can (i) enhance activation of 5-HT... 
Journal Article