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American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 09/2015, Volume 309, Issue 7, pp. E679 - E690
AMP-activated protein kinase (AMPK) is a major sensor of energy homeostasis and stimulates ATP-generating processes such as lipid oxidation and glycolysis in... 
AMP-activated protein kinase | Metabolism | Skeletal muscle | skeletal muscle | metabolism
Journal Article
PLoS Medicine, ISSN 1549-1277, 05/2007, Volume 4, Issue 5, pp. 0868 - 0879
Background Type 2 diabetes mellitus ( T2DM) is characterized by defects in insulin secretion and action. Impaired glucose uptake in skeletal muscle is believed... 
MEDICINE, GENERAL & INTERNAL | HYPERGLYCEMIA | SKELETAL-MUSCLE CELLS | INSULIN-RESISTANCE | THIOREDOXIN-INTERACTING PROTEIN | MICE | DIFFERENTIATION | IDENTIFICATION | EXPRESSION | ASSOCIATION | DIABETES-SUSCEPTIBILITY GENES | Diabetes Mellitus, Type 2 - genetics | Humans | Qb-SNARE Proteins - genetics | Adipocytes - cytology | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Polymerase Chain Reaction | Carrier Proteins - physiology | Insulin - pharmacology | Genetic Predisposition to Disease | Glucose Intolerance - genetics | Cells, Cultured | Gene Expression Regulation - physiology | DNA-Binding Proteins - genetics | Hypoglycemic Agents - pharmacology | Linkage Disequilibrium | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Diabetes Mellitus, Type 2 - physiopathology | Promoter Regions, Genetic - physiology | Homeostasis - physiology | Protein Array Analysis | Blood Glucose - genetics | Polymorphism, Single Nucleotide | Glucose Clamp Technique | Muscle, Skeletal - pathology | Blood Glucose - metabolism | Proto-Oncogene Proteins c-bcl-6 | Proteins | Glucose metabolism | Medical research | Medicine, Experimental | Gene expression | Observations | Health aspects | Index Medicus | Nutrition and Metabolism | Genetics and Genomics | Genetics | Physiology | Diabetes | Diabetes and Endocrinology | Endocrinology | Clinical Medicine | Endokrinologi och diabetes | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2018, Volume 115, Issue 9, pp. E2048 - E2057
Journal Article
Journal Article
eLife, ISSN 2050-084X, 2014, Volume 3, pp. e03245 - e03245
Obesity is associated with blunted beta-adrenoreceptor (beta-AR)-mediated lipolysis and lipid oxidation in adipose tissue, but the mechanisms linking nutrient... 
adipose tissue | TGF-beta | chemical-genetic | beta-adrenergic | lipolysis | obesity | NERVOUS-SYSTEM | METABOLIC SYNDROME | ACTIVATED RECEPTOR-GAMMA | SMAD PROTEINS | INHIBIN BETA-B | MITOCHONDRIAL BIOGENESIS | INSULIN-RESISTANCE | BIOLOGY | DOWN-REGULATION | DIET-INDUCED OBESITY | ADIPOSE-TISSUE | Activin Receptors, Type I - antagonists & inhibitors | Lipolysis - drug effects | Catecholamines - metabolism | Humans | Obesity - genetics | Adipose Tissue - metabolism | Adenosine Triphosphate - antagonists & inhibitors | Adenosine Triphosphate - metabolism | Diet, High-Fat | Lipid Peroxidation - drug effects | Obesity - etiology | Receptors, Adrenergic, beta - metabolism | Pyrazoles - pharmacology | Dietary Fats - adverse effects | Signal Transduction | Activin Receptors, Type I - deficiency | Adipose Tissue - pathology | Gene Expression Regulation | Pyrimidines - pharmacology | Activin Receptors, Type I - genetics | Adipocytes - pathology | Mice, Knockout | Obesity - pathology | Mitochondrial Turnover - drug effects | Animals | Receptors, Adrenergic, beta - genetics | Transforming Growth Factor beta - genetics | Adipocytes - metabolism | Obesity - prevention & control | Mice | Primary Cell Culture | Transforming Growth Factor beta - metabolism | Obesity | Nuclear magnetic resonance--NMR | Adipose tissue | Body fat | Lipid peroxidation | Energy expenditure | Nervous system | Adipocytes | Kinases | Insulin | Lipolysis | High fat diet | Mitochondria | Sodium | Plasmids | Rodents | Physiology | Oxidation | Adrenergic receptors | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Physiological Reports, ISSN 2051-817X, 04/2015, Volume 3, Issue 4, pp. e12372 - n/a
Diacylglycerol kinase ( DGK ) isoforms regulate signal transduction and lipid metabolism. DGK δ deficiency leads to hyperglycemia, peripheral insulin... 
skeletal muscle | liver | Adipose tissue | Liver | Skeletal muscle | Obesity | Animal models | Diacylglycerol kinase | Soleus muscle | Gene expression | Metabolism | Insulin | Signal transduction | Hyperglycemia | Isoforms | Insulin resistance | Transduction | Lipid metabolism
Journal Article
Journal Article
Acta Physiologica, ISSN 1748-1708, 06/2010, Volume 199, Issue 2, pp. 221 - 230
Aim:  To examine the phenotype of mice that lack the adenosine A3 receptor (A3R). Methods:  We examined the heart rate, body temperature and locomotion... 
body weight | heat production | knock-out | diurnal | sex differences | Sex differences | Diurnal | Body weight | Knock-out | Heat production
Journal Article
American Journal of Physiology, ISSN 0193-1849, 10/2015, Volume 309, Issue 7, p. E679
  AMP-activated protein kinase (AMPK) is a major sensor of energy homeostasis and stimulates ATP-generating processes such as lipid oxidation and glycolysis in... 
Phosphorylation | Bioenergetics | Rodents | Homeostasis | Kinases | Adenosine triphosphatase | Binding sites
Journal Article
American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 08/2012, Volume 303, Issue 4, pp. E524 - E533
Szekeres F, Chadt A, Tom RZ, Deshmukh AS, Chibalin AV, Bjornholm M, Al-Hasani H, Zierath JR. The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle... 
Insulin resistance | Glucose transport | Glucose transporter 4 | Adenosine 5′-monophosphate-activated protein kinase | glucose transport | PHYSIOLOGY | AS160 | PHOSPHORYLATION | glucose transporter 4 | ACETYL-COA CARBOXYLASE | AKT SUBSTRATE | TRANSPORT | CONTRACTION | GLUT4 TRANSLOCATION | INSULIN-RESISTANCE | 14-3-3 BINDING | ENDOCRINOLOGY & METABOLISM | adenosine 5 '-monophosphate-activated protein kinase | insulin resistance | KINASE ACTIVATION | Deoxyglucose - metabolism | Gluconeogenesis - drug effects | Male | Muscle, Skeletal - metabolism | GTPase-Activating Proteins - metabolism | Glucose Transporter Type 4 - analysis | Insulin - blood | Aminoimidazole Carboxamide - pharmacology | Ribonucleotides - pharmacology | Liver - drug effects | Fasting - blood | Muscle, Skeletal - drug effects | Biological Transport - drug effects | Fasting - metabolism | Nuclear Proteins - genetics | Insulin - pharmacology | Glucose Tolerance Test | Liver - metabolism | Nuclear Proteins - metabolism | Hypoglycemic Agents - pharmacology | Gluconeogenesis - physiology | Animals | Aminoimidazole Carboxamide - analogs & derivatives | Signal Transduction - drug effects | Muscle Contraction - drug effects | Glucose - metabolism | Mice | Muscles | Glucose metabolism | Protein research | Observations | Analysis | Proteins | Musculoskeletal system | Liver | Rodents | Glucose | Metabolism | Insulin | Index Medicus | Basic Medicine | Physiology | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Fysiologi
Journal Article