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Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2011, Volume 54, Issue 6, pp. 1812 - 1824
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 07/2013, Volume 4, Issue 7, pp. 606 - 611
A series of 2-hydroxy-1,3-dioxoisoquinoline-4-carboxamides featuring an N-hydroxyimide chelating functionality was evaluated for their inhibitory properties... 
antiretroviral | HIV | 2-hydroxy-1,3- dioxoisoquinoline-4-carboxamide | 3′ processing | integrase | DESIGN | CHEMISTRY, MEDICINAL | REVERSE-TRANSCRIPTASE | 2-hydroxy-1,3-dioxoisoquinoline-4-carboxamide | 3 ' processing | RESISTANCE PROFILE | DUAL INHIBITORS | S/GSK1349572 | DISCOVERY
Journal Article
Journal Article
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2014, Volume 57, Issue 11, pp. 4640 - 4660
We report herein further insight into the biological activities displayed by a series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs). Substitution of the... 
RNASE-H | CHEMISTRY, MEDICINAL | RALTEGRAVIR | SMALL-MOLECULE INHIBITORS | DOCKING | RESISTANCE PROFILE | DRUG-RESISTANCE | STRAND TRANSFER | HIV-1 REPLICATION | DOLUTEGRAVIR S/GSK1349572 | DISCOVERY
Journal Article
Journal Article
MOLECULES, ISSN 1420-3049, 10/2019, Volume 24, Issue 20, p. 3675
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 11/2014, Volume 42, Issue 20, pp. 12352 - 12366
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 2005, Volume 99, Issue 1, pp. 83 - 91
Journal Article
Physical Chemistry Chemical Physics, ISSN 1463-9076, 2017, Volume 19, Issue 28, pp. 18452 - 18460
The impact of the amino-acid side-chain length on peptide-RNA binding events has been investigated using HIV-1 Tat derived peptides as ligands and the HIV-1... 
DESIGN | VIRUS | THERMODYNAMICS | HIV-1 TAR RNA | SMALL MOLECULES | TRANSCRIPTION | FLEXIBILITY | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | EFFICIENT SYNTHESIS | CHEMISTRY, PHYSICAL | INDUCED FIT | PROTEIN RECOGNITION
Journal Article
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 11/2014, Volume 42, Issue 20, pp. 12352 - 12366
Journal Article