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Nature, ISSN 0028-0836, 01/2011, Volume 469, Issue 7328, pp. 102 - 107
Journal Article
Nature, ISSN 0028-0836, 02/2011, Volume 470, Issue 7334, pp. 359 - 365
Telomere dysfunction activates p53-mediated cellular growth arrest, senescence and apoptosis to drive progressive atrophy and functional decline in... 
STEM-CELLS | HEPATOCELLULAR-CARCINOMA | BIOGENESIS | PGC-1-ALPHA | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | LEADS | MICE | DAMAGE | P53 | COACTIVATORS | Cell Proliferation | Reactive Oxygen Species - metabolism | Hematopoietic Stem Cells - pathology | DNA, Mitochondrial - analysis | Adenosine Triphosphate - biosynthesis | Tumor Suppressor Protein p53 - genetics | RNA - genetics | Telomerase - deficiency | Cardiomyopathies - physiopathology | Telomerase - genetics | Myocardium - metabolism | Telomere - metabolism | Gluconeogenesis | Telomere - genetics | Liver - metabolism | Tumor Suppressor Protein p53 - metabolism | Cardiomyopathies - pathology | Transcription Factors - antagonists & inhibitors | Hematopoietic Stem Cells - metabolism | Mitochondria - metabolism | Mitochondria - pathology | Tumor Suppressor Protein p53 - deficiency | Doxorubicin - toxicity | Aging - pathology | Myocardium - cytology | Transcription Factors - metabolism | Telomere - pathology | Animals | Cardiomyopathies - metabolism | Telomere - enzymology | Liver - cytology | Mice | Aging - metabolism | Cardiomyopathies - chemically induced | Telomeres | Mitochondria | Genetic aspects | Chemical properties | Abnormalities | Liver | Cell division | Mitochondrial DNA | Biosynthesis | Biology | DNA repair | Proteins | Studies | Aging | Telomerase | Binding sites | Apoptosis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2014, Volume 111, Issue 8, pp. 3128 - 3133
Journal Article
Cell, ISSN 0092-8674, 02/2012, Volume 148, Issue 4, pp. 651 - 663
Journal Article
Cell, ISSN 0092-8674, 03/2012, Volume 148, Issue 5, pp. 896 - 907
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 20, Issue 1, pp. 92 - 103
Journal Article
Molecular Cancer Research, ISSN 1541-7786, 01/2019, Volume 17, Issue 1, pp. 199 - 211
The most frequent genetic alterations in melanoma are gain-of-function (GOF) mutations in BRAF, which result in RAF-MEK-ERK signaling pathway addiction.... 
MEK | INHIBITION | MUTATIONS CONFER RESISTANCE | GENE | ONCOLOGY | PATHWAY | RAF | DRUG-ADDICTION | ACQUIRED-RESISTANCE | BRAF | VEMURAFENIB | CELL BIOLOGY
Journal Article
Cancer Research, ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 965 - 965
Journal Article
2004, AD-a425 895.
Chromatin structure has a strong influence on the regulation of all nuclear processes in which access to DNA is required, such as transcription, replication... 
genome | dsb(double-strand break) | recombination reactions | deoxyribonucleic acids | cells(biology) | enzymes | chromatin
Government Document
2003, AD-a416 619.
Chromosomal double-strand breaks (DSBs) can arise from cellular DNA metabolism and from eogenous DNA-damaging agents. Efficient repair of these DSBs is... 
damage | repair | efficiency | cells(biology) | chromatin | chemical agents | suppressors | genome | mammals | deoxyribonucleic acids | metabolism | neoplasms | stability
Government Document
Molecular and Cellular Biology, ISSN 0270-7306, 05/2000, Volume 20, Issue 9, pp. 3058 - 3068
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 444 - 444
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2014, Volume 111, Issue 8, p. 3128
  Defects in epigenetic regulation play a fundamental role in the development of cancer, and epigenetic regulators have recently emerged as promising... 
Cell growth | Chromatin | Epigenetics | Mutation | Cells | Tumors | Cancer
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 02/2014, Volume 111, Issue 8, pp. 3128 - 3128
Defects in epigenetic regulation play a fundamental role in the development of cancer, and epigenetic regulators have recently emerged as promising therapeutic... 
Journal Article