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British Journal of Haematology, ISSN 0007-1048, 03/2014, Volume 164, Issue 6, pp. 767 - 778
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 15, pp. 1547 - 1555
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2013, Volume 123, Issue 6, pp. 2395 - 2407
Journal Article
Leukemia & Lymphoma, ISSN 1042-8194, 09/2017, Volume 58, Issue 9, pp. 2026 - 2039
The approval of venetoclax, a 'BH3-mimetic' antagonist of the BCL-2 anti-apoptotic protein, for chronic lymphocytic leukemia represents a major milestone in... 
BCL-2 | rational combinations | BCL-XL | MCL-1 | Venetoclax | resistance | BCL-X-L | MANTLE-CELL LYMPHOMA | ACUTE MYELOGENOUS LEUKEMIA | ACUTE MYELOID-LEUKEMIA | ENDOPLASMIC-RETICULUM STRESS | DEPENDENT KINASE INHIBITOR | BRUTON TYROSINE KINASE | ONCOLOGY | BH3-ONLY PROTEIN NOXA | CHRONIC LYMPHOCYTIC-LEUKEMIA | BH3 MIMETIC ABT-199 | HEMATOLOGY | Neoplasms - metabolism | Apoptosis - drug effects | Humans | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | bcl-X Protein - genetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Apoptosis - genetics | Peptide Fragments - pharmacology | Antineoplastic Agents - therapeutic use | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Biomimetics | Neoplasms - genetics | Bridged Bicyclo Compounds, Heterocyclic - therapeutic use | bcl-X Protein - antagonists & inhibitors | Proto-Oncogene Proteins - therapeutic use | Proto-Oncogene Proteins c-bcl-2 - chemistry | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - antagonists & inhibitors | Clinical Trials as Topic | Sulfonamides - pharmacology | Drug Discovery | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Neoplasms - drug therapy | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Sulfonamides - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Peptide Fragments - therapeutic use | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | bcl-X Protein - metabolism
Journal Article
The Lancet Oncology, ISSN 1470-2045, 02/2018, Volume 19, Issue 2, pp. 216 - 228
Journal Article
Blood, ISSN 0006-4971, 09/2016, Volume 128, Issue 10, pp. 1316 - 1317
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2010, Volume 120, Issue 1, pp. 142 - 156
Journal Article
Blood, ISSN 0006-4971, 10/2015, Volume 126, Issue 16, pp. 1874 - 1875
Journal Article