eLife, ISSN 2050-084X, 12/2019, Volume 8
The spatial distribution of atrophy in neurodegenerative diseases suggests that brain connectivity mediates disease propagation. Different descriptors of the...
Journal Article
Information processing in medical imaging : proceedings of the ... conference, ISSN 1011-2499, 2015, Volume 24, pp. 711 - 722
The event-based model constructs a discrete picture of disease progression from cross-sectional data sets, with each event corresponding to a new biomarker...
Alzheimer Disease - etiology | Reproducibility of Results | Humans | Image Interpretation, Computer-Assisted - methods | Magnetic Resonance Imaging - methods | Cognitive Dysfunction - pathology | Subtraction Technique | Disease Progression | Alzheimer Disease - pathology | Algorithms | Sensitivity and Specificity | Brain - pathology | Image Enhancement - methods | Cognitive Dysfunction - complications | Pattern Recognition, Automated - methods
Alzheimer Disease - etiology | Reproducibility of Results | Humans | Image Interpretation, Computer-Assisted - methods | Magnetic Resonance Imaging - methods | Cognitive Dysfunction - pathology | Subtraction Technique | Disease Progression | Alzheimer Disease - pathology | Algorithms | Sensitivity and Specificity | Brain - pathology | Image Enhancement - methods | Cognitive Dysfunction - complications | Pattern Recognition, Automated - methods
Journal Article
Annals of Clinical and Translational Neurology, ISSN 2328-9503, 05/2018, Volume 5, Issue 5, pp. 570 - 582
Objective Determining the sequence in which Huntington's disease biomarkers become abnormal can provide important insights into the disease progression and a...
NEURODEGENERATIVE DISEASE | TRACK-HD | DIAGNOSIS | OBSERVATIONAL DATA | SPORADIC ALZHEIMERS-DISEASE | COGNITIVE IMPAIRMENT | PREMANIFEST | NEUROSCIENCES | ONSET | PROGRESSION | CLINICAL NEUROLOGY | PREDICTION | Huntingtons disease
NEURODEGENERATIVE DISEASE | TRACK-HD | DIAGNOSIS | OBSERVATIONAL DATA | SPORADIC ALZHEIMERS-DISEASE | COGNITIVE IMPAIRMENT | PREMANIFEST | NEUROSCIENCES | ONSET | PROGRESSION | CLINICAL NEUROLOGY | PREDICTION | Huntingtons disease
Journal Article
Brain, ISSN 0006-8950, 06/2018, Volume 141, Issue 6, pp. 1665 - 1677
See Stankoff and Louapre (doi:10.1093/brain/awy114) for a scientific commentary on this article. Grey matter atrophy is present from the earliest stages of...
Clinical Neurology | b_open_article_in_toll_access_journal | multiple sclerosis | atrophy | probabilistic modelling | disability accumulation | grey matter | ALZHEIMERS-DISEASE | SPINAL-CORD | NEURODEGENERATION | MENINGEAL INFLAMMATION | NEUROSCIENCES | DAMAGE | CLINICAL NEUROLOGY | DEMYELINATION | CEREBELLAR CORTEX | DISABILITY | BRAIN | Original
Clinical Neurology | b_open_article_in_toll_access_journal | multiple sclerosis | atrophy | probabilistic modelling | disability accumulation | grey matter | ALZHEIMERS-DISEASE | SPINAL-CORD | NEURODEGENERATION | MENINGEAL INFLAMMATION | NEUROSCIENCES | DAMAGE | CLINICAL NEUROLOGY | DEMYELINATION | CEREBELLAR CORTEX | DISABILITY | BRAIN | Original
Journal Article
Nature Communications, ISSN 2041-1723, 10/2018, Volume 9, Issue 1, pp. 4273 - 16
textabstractThe heterogeneity of neurodegenerative diseases is a key confound to disease understanding and treatment development, as study cohorts typically...
COGNITIVE DECLINE | REPEAT EXPANSIONS | DEMENTIA | DEFINED SUBTYPES | MULTIDISCIPLINARY SCIENCES | SPORADIC ALZHEIMERS-DISEASE | ATROPHY PATTERNS | BIOMARKER CHANGES | MODEL | FRONTOTEMPORAL LOBAR DEGENERATION | HUNTINGTONS-DISEASE | Frontotemporal Dementia - genetics | Phenotype | Reproducibility of Results | Neurodegenerative Diseases - pathology | Time Factors | Humans | Genotype | Models, Neurological | Alzheimer Disease - genetics | Alzheimer Disease - pathology | Frontotemporal Dementia - pathology | Neurodegenerative Diseases - classification | Phenotypes | Medical imaging | Disease | Neurodegenerative diseases | Medical treatment | Inference | Trajectories | Patients | Subgroups | Complexity | Diseases | Neurological diseases | Heterogeneity | Learning algorithms | Neurodegeneration | Machine learning | Dementia disorders | Diagnostic systems | Frontotemporal dementia | Genotypes
COGNITIVE DECLINE | REPEAT EXPANSIONS | DEMENTIA | DEFINED SUBTYPES | MULTIDISCIPLINARY SCIENCES | SPORADIC ALZHEIMERS-DISEASE | ATROPHY PATTERNS | BIOMARKER CHANGES | MODEL | FRONTOTEMPORAL LOBAR DEGENERATION | HUNTINGTONS-DISEASE | Frontotemporal Dementia - genetics | Phenotype | Reproducibility of Results | Neurodegenerative Diseases - pathology | Time Factors | Humans | Genotype | Models, Neurological | Alzheimer Disease - genetics | Alzheimer Disease - pathology | Frontotemporal Dementia - pathology | Neurodegenerative Diseases - classification | Phenotypes | Medical imaging | Disease | Neurodegenerative diseases | Medical treatment | Inference | Trajectories | Patients | Subgroups | Complexity | Diseases | Neurological diseases | Heterogeneity | Learning algorithms | Neurodegeneration | Machine learning | Dementia disorders | Diagnostic systems | Frontotemporal dementia | Genotypes
Journal Article
ISSN 2041-1723, 2018
The heterogeneity of neurodegenerative diseases is a key confound to disease understanding and treatment development, as study cohorts typically include...
Neurodegenerative Diseases | Genetic FTD Initiative (GENFI) | Reproducibility of Results | Phenotype | Frontotemporal Dementia | Time Factors | Humans | Genotype | Models, Neurological | Alzheimer’s Disease Neuroimaging Initiative (ADNI) | Alzheimer Disease
Neurodegenerative Diseases | Genetic FTD Initiative (GENFI) | Reproducibility of Results | Phenotype | Frontotemporal Dementia | Time Factors | Humans | Genotype | Models, Neurological | Alzheimer’s Disease Neuroimaging Initiative (ADNI) | Alzheimer Disease
Journal Article
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), ISSN 0302-9743, 2015, Volume 9123, pp. 711 - 722
Journal Article
05/2019
We present BrainPainter, a software that automatically generates images of highlighted brain structures given a list of numbers corresponding to the output...
Journal Article
01/2019
Medical Image Computing and Computer Assisted Intervention 2019 We introduce Disease Knowledge Transfer (DKT), a novel technique for transferring biomarker...
Journal Article
10.
Full Text
DIVE: A spatiotemporal progression model of brain pathology in neurodegenerative disorders
NeuroImage, ISSN 1053-8119, 05/2019, Volume 192, pp. 166 - 177
Current models of progression in neurodegenerative diseases use neuroimaging measures that are averaged across pre-defined regions of interest (ROIs). Such...
Vertex-wise measures | Cortical thickness | Posterior cortical atrophy | Alzheimer's disease | Disease progression model | MILD | ATROPHY | ALZHEIMERS-DISEASE | NEUROSCIENCES | NEUROIMAGING | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Medical research | Nervous system diseases | Multiple sclerosis | Singers | Medicine, Experimental | Epidemiology | Neuroimaging | Compression | Nuclear magnetic resonance--NMR | Cognitive ability | Clinical trials | Atrophy | Scholarships & fellowships | Dementia disorders | Amyloid | Age | Cortex (temporal) | Medical imaging | Neurodegenerative diseases | Cortex | Brain mapping | Grants | Pathology | Brain research | Spatial distribution | Magnetic resonance imaging | Anisotropy | Neural networks | Biomarkers | Alzheimers disease | Positron emission tomography | Dementia
Vertex-wise measures | Cortical thickness | Posterior cortical atrophy | Alzheimer's disease | Disease progression model | MILD | ATROPHY | ALZHEIMERS-DISEASE | NEUROSCIENCES | NEUROIMAGING | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Medical research | Nervous system diseases | Multiple sclerosis | Singers | Medicine, Experimental | Epidemiology | Neuroimaging | Compression | Nuclear magnetic resonance--NMR | Cognitive ability | Clinical trials | Atrophy | Scholarships & fellowships | Dementia disorders | Amyloid | Age | Cortex (temporal) | Medical imaging | Neurodegenerative diseases | Cortex | Brain mapping | Grants | Pathology | Brain research | Spatial distribution | Magnetic resonance imaging | Anisotropy | Neural networks | Biomarkers | Alzheimers disease | Positron emission tomography | Dementia
Journal Article
05/2018
The Alzheimer's Disease Prediction Of Longitudinal Evolution (TADPOLE) Challenge compares the performance of algorithms at predicting future evolution of...
Journal Article
BRAIN, ISSN 0006-8950, 07/2019, Volume 142, Issue 7, pp. 2082 - 2095
Posterior cortical atrophy is a clinico-radiological syndrome characterized by progressive decline in visual processing and atrophy of posterior brain regions....
structural MRI | memory | brain atrophy | ALZHEIMERS-DISEASE | DISCONNECTION | CLINICAL CHARACTERISTICS | PHENOTYPES | MODEL | SPAN | DISTINCT PATTERNS | NEUROSCIENCES | VISUAL VARIANT | CLINICAL NEUROLOGY | PROFILE | dementia | Alzheimer's disease | Alzheimer’s disease | Editor's Choice | Original
structural MRI | memory | brain atrophy | ALZHEIMERS-DISEASE | DISCONNECTION | CLINICAL CHARACTERISTICS | PHENOTYPES | MODEL | SPAN | DISTINCT PATTERNS | NEUROSCIENCES | VISUAL VARIANT | CLINICAL NEUROLOGY | PROFILE | dementia | Alzheimer's disease | Alzheimer’s disease | Editor's Choice | Original
Journal Article
Revista de Chimie, ISSN 0034-7752, 03/2018, Volume 69, Issue 3, pp. 587 - 590
There is no consensus among ENT (ear, nose and throat) physicians on the causes, diagnosis and especially therapeutic approach in sensorineural hearing loss...
Intratympanic injection | Ent | Dexamethasone | Sudden sensorineural hearing loss | dexamethasone | ENGINEERING, CHEMICAL | INJECTION | sudden sensorineural hearing loss | ENT | intratympanic injection | CHEMISTRY, MULTIDISCIPLINARY
Intratympanic injection | Ent | Dexamethasone | Sudden sensorineural hearing loss | dexamethasone | ENGINEERING, CHEMICAL | INJECTION | sudden sensorineural hearing loss | ENT | intratympanic injection | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Oncology Letters, ISSN 1792-1074, 05/2016, Volume 11, Issue 5, pp. 3354 - 3360
Regression in melanoma is a frequent biological event of uncertain prognostic value as the lesion exhibits heterogeneous phenotypical features, both at the...
Tissue inhibitors of metalloproteinases | Melanoma with regression | Prognosis | CONFERS ANOIKIS RESISTANCE | HISTOLOGICAL REGRESSION | METASTASES | MARKERS | METALLOPROTEINASES | prognosis | CANCER | melanoma with regression | tissue inhibitors of metalloproteinases | ONCOLOGY | SULFATE | MALIGNANT MELANOMAS | TISSUE INHIBITOR | ASSOCIATION
Tissue inhibitors of metalloproteinases | Melanoma with regression | Prognosis | CONFERS ANOIKIS RESISTANCE | HISTOLOGICAL REGRESSION | METASTASES | MARKERS | METALLOPROTEINASES | prognosis | CANCER | melanoma with regression | tissue inhibitors of metalloproteinases | ONCOLOGY | SULFATE | MALIGNANT MELANOMAS | TISSUE INHIBITOR | ASSOCIATION
Journal Article
Romanian Neurosurgery, ISSN 1220-8841, 03/2018, Volume 32, Issue 1, pp. 29 - 34
Cerebral activity is extremely complex and requires a super diagnosis investigation - there is no limit to this super investigation, especially in the case of...
operating microscop | science-fiction | MRI | hibryd OP room | future | neuronavigation | OP theather | neurosurgery | robotic surgery
operating microscop | science-fiction | MRI | hibryd OP room | future | neuronavigation | OP theather | neurosurgery | robotic surgery
Journal Article
Key Engineering Materials, ISSN 1013-9826, 09/2013, Volume 583, pp. 41 - 44
Metallic implants for ostheosynthesis are used for temporary replacement of the the original functions and to accelerate the bone consolidation after fracture....
Design | Ostheosynthesis | Stainless steels | Surgical implants | Correlation | Fracture mechanics | Human body | Bones | Patients | Metal ions
Design | Ostheosynthesis | Stainless steels | Surgical implants | Correlation | Fracture mechanics | Human body | Bones | Patients | Metal ions
Journal Article
International Journal of Medical Dentistry, ISSN 2066-6063, 04/2018, Volume 8, Issue 2, pp. 34 - 37
The term "stent" was slowly absorbed and later monopolized by general medicine during the First World War with the increase of reconstructive interventions...
Prostheses | Dictionaries | Angioplasty | World War I | Plastic surgery | Dentistry | Urology | Pathology | Inventors | Implants | Endoscopy | Stents | 19th century | Dentists
Prostheses | Dictionaries | Angioplasty | World War I | Plastic surgery | Dentistry | Urology | Pathology | Inventors | Implants | Endoscopy | Stents | 19th century | Dentists
Journal Article
Dilema, ISSN 1221-3055, 2003, Issue 539, pp. 7 - 11
"What Are We Eating?" is the theme proposed by Dilema magazine for this issue. Some authors tried to write about such a problem in these days of "fast food"...
Anthropology
Anthropology
Journal Article
01/2006
Finite element modeling (FEM) provides a full-field method for describing the stress and strain environment of the bone. The main objectives of the current...
Biomedical research
Biomedical research
Dissertation
Studii şi Materiale de Istorie Medie (SMIM), ISSN 1222-4766, 2005, Issue XXIII, pp. 79 - 100
La découverte du document du 22 mars 1660, dans les archives de la monastère Vatoped du Mont Athos, où le prince Ştefăniţă Lupu renforce le droit de propriété...
History
History
Journal Article
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