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IUBMB Life, ISSN 1521-6543, 12/2019, Volume 71, Issue 12, pp. 1834 - 1845
Colorectal cancer (CRC) is one of the most common malignancies in the world. Despite intensive advances in diagnosis and treatment of CRC, it is yet one of the... 
Hsp70 | cancer | inhibitor | colorectal
Journal Article
by Dunning, Alison and Michailidou, Kyriaki and Kuchenbaecker, Karoline and Thompson, Deborah and French, Juliet and Beesley, Jonathan and Healey, Sue and Kar, Siddhartha and Pooley, Karen and Lopez-Knowles, Elena and Dicks, Ed and Barrowdale, Daniel and Sinnott-Armstrong, Nicholas A and Sallari, Richard C and Hillman, Kristine and Kaufmann, Susanne and Sivakumaran, Haran and Marjaneh, Mahdi Moradi and Lee, Jason and Hills, Margaret and Jarosz, Monika and ry, Suzie and Canisius, Sander and KBolla, Manjeet and Dennis, Joe and Wang, Qin and LHopper, John and Southey, Mellissa C and Broeks, Annegien and Schmidt, Marjanka and Lophatananon, Artitaya and Muir, K and Beckmann, Matthias and Fasching, Peter and Santos Silva, Isabel and Peto, Julian and Sawyer, Elinor and Tomlinson, Ian and Burwinkel, Barbara and Marme, Federick and Guénel, Pascal and Truong, Thérèse and Bojesen, Stig and Flyger, Henrik and Gonzlez-Neira, Anna and Perez, Jose I.A and Anton-Culver, Hoda and Eunjung, Lee and Arndt, Volker and Brenner, Hermann and Meindl, Alfons and Schmutzler, Rita and Brauch, Hiltrud and Hamann, Ute and Aittomki, Kristiina and Blomqvist, Carl and Ito, Hidemi and Matsuo, Keitaro and Bogdanova, Natalia and Dörk, Thilo and Lindblom, Annika and Margolin, Sara and Kosma, Veli-Matti and Mannermaa, Arto and Tseng, Chiu-Chen and Wu, Anna and Lambrechts, Diether and Wildiers, Hans and Chang-Claude, Jenny and Rudolph, Anja and Peterlongo, Paolo and Radice, Paolo and EOlson, Janet and GGiles, Graham and Milne, Roger L and Haiman, Christopher A and Henderson, Brian and Goldberg, Mark and Teo, Soo Hwang and Yip, Cheng Har and Nord, Silje and Borresen-Dale, Anne-Lise and Kristensen, Vessela and Long, Jirong and Zheng, Wei and Pylks, Katri and Winqvist, Robert and Anulis, Irene and Knight, Julia A and Devilee, Peter and Seynaeve, Caroline and Figueroa, Jonine and Sherman, Mark and Czene, Kamila and Darabi, Hatef and Hollestelle, Antoinette and Ouweland, Ans and Humphreys, Keith and Gao, Yu-Tang and Shu, Xiao-Ou and ... and KConFab Investigators and HEBON and EMBRACE and GEMO Study Collaborators and kConFab Investigators and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för immunologi, genetik och patologi and Uppsala universitet
Nature Genetics, ISSN 1061-4036, 03/2016, Volume 48, Issue 4, pp. 374 - 386
Journal Article
by Ghoussaini, Maya and French, Juliet and Michailidou, Kyriaki and Nord, Silje and Beesley, Jonathan and Canisus, S and Hillman, Kristine and Kaufmann, Susanne and Sivakumaran, Haran and Moradi Marjaneh, M and Lee, Jason and Dennis, Joe and Bolla, Manjeet K and Wang, Q and Dicks, Ed and Milne, Roger and Hopper, J.L and Southey, M.C and Schmidt, Marjanka and Broeks, Annegien and Muir, K and Lophatananon, Artitaya and Fasching, Peter and Beckmann, Matthias and Fletcher, Olivia and Johnson, N and Sawyer, Elinor and Tomlinson, Ian and Burwinkel, Barbara and Marme, F and Guénel, Pascal and Truong, Thérèse and Bojesen, Stig and Flyger, Henrik and Benítez, Javier and González-Neira, Anna and Alonso, Rosario and Pita, Guillermo and Neuhausen, Susan and Anton-Culver, Hoda and Brenner, Hermann and Arndt, V and Meindl, Alfons and Schmutzler, Rita and Brauch, Hiltrud and Hamann, Ute and Tessier, Daniel C and Vincent, Daniel and Nevanlinna, Heli and Khan, Sofia and Matsuo, K and Ito, Hidemi and Dörk, Thilo and Bogdanova, Natalia and Lindblom, Annika and Margolin, Sara and Mannermaa, Arto and Kosma, Veli-Matti and Wu, Anna and Van Den Berg, David and Lambrechts, D and Floris, O.A.M and Chang-Claude, Jenny and Rudolph, A and Radice, Paolo and Barile, Monica and Couch, Fergus and Hallberg, E and Giles, G.G and Haiman, Christopher A and Le Marchand, Loic and Goldberg, Mark and Teo, Soo-Hwang and Yip, Cheng Har and Borresen-Dale, Anne-Lise and Zheng, Wei and Cai, Qiuyin and Winqvist, Robert and Pykäs, Katri and Anulis, Irene and Devilee, Peter and Tollenaar, Rob and García-Closas, Montserrat and Figueroa, Jonine and Hall, Per and Czene, Kamila and Brand, Judith S and Darabi, Hatef and Eriksson, Mats and Hooning, Maartje and Koppert, L.B and Li, Jingmei and Shu, Xiao-Ou and Zheng, Ying and Cox, Angela and Cross, Simon and Shah, M and Rhenius, Valerie and Choi, J.-Y and Kang, Daehee and ...
American Journal of Human Genetics, ISSN 0002-9297, 10/2016, Volume 99, Issue 4, pp. 903 - 911
textabstractGenome-wide association studies (GWASs) have revealed increased breast cancer risk associated with multiple genetic variants at 5p12. Here, we... 
Receptors | Genetic variation | Estrogen | Disease susceptibility | Genetic aspects | Breast cancer | Genetic regulation | Health aspects
Journal Article
by Darabi, Hatef and Beesley, Jonathan and it, Arnaud and Kar, Siddhartha and Nord, Silje and Marjaneh, Mahdi Moradi and Soucy, P and Michailidou, Kyriaki and Ghoussaini, Maya and Wahl, H.F and Bolla, Manjeet K and Wang, Q and Dennis, Joe and Alonso, Rosario and Anulis, Irene and Anton-Culver, Hoda and Arndt, V and Beckmann, Matthias and Benítez, Javier and Bogdanova, Natalia and Bojesen, Stig and Brauch, Hiltrud and Brenner, Hermann and Broeks, Annegien and Brüning, Thomas and Burwinkel, Barbara and Chang-Claude, Jenny and Choi, J.-Y and Conroy, Don and Couch, Fergus and Cox, Angela and Cross, Simon and Czene, Kamila and Devilee, Peter and Dörk, Thilo and Easton, Douglas F and Fasching, Peter and Figueroa, Jonine and Fletcher, Olivia and Flyger, Henrik and Galle, E and García-Closas, Montserrat and Giles, G.G and Goldberg, Mark and González-Neira, Anna and Guénel, Pascal and Haiman, Christopher A and Hallberg, E and Hamann, Ute and Hartman, Joost and Hollestelle, Antoinette and Hopper, John and Ito, Hidemi and Jakubowska, Anna and Johnson, N and Kang, Daehee and Khan, Sofia and Kosma, Veli-Matti and Kriege, M and Kristensen, Vessela and Lambrechts, D and Le Marchand, Loic and Lee, S.C and Lindblom, Annika and Lophatananon, Artitaya and Lubinski, Jan and Mannermaa, Arto and Manoukian, Siranoush and Margolin, Sara and Matsuo, Keitaro and Mayes, R and McKay, J and Meindl, Alfons and Milne, Roger and Muir, K and Neuhausen, Susan and Nevanlinna, Heli and Olswold, Curtis and Orr, N and Peterlongo, Paolo and Pita, Guillermo and Pykäs, Katri and Rudolph, A and Sangrajrang, S and Sawyer, E.J and Schmidt, Marjanka and Schmutzler, Rita and Seynaeve, Caroline and Shah, M and Shen, Chen-Yang and Shu, Xiao-Ou and Southey, Melissa and Stram, D.O and Surowy, Harald and Swerdlow, Anthony and Teo, Soo-Hwang and Tessier, Daniel C and Tomlinson, Ian and Torres, Diana and Truong, Thérèse and ...
Scientific Reports, ISSN 2045-2322, 09/2016, Volume 6, Issue 1, p. 32512
textabstractGenome-wide association studies have found SNPs at 17q22 to be associated with breast cancer risk. To identify potential causal variants related to... 
RISK LOCUS | CONSORTIUM | FUNCTIONAL VARIANTS | HUMAN GENOME | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | ENHANCERS | EXPRESSION | ASSOCIATION | REVEALS | REGION | Genotyping | Introns | Lead | Breast cancer | Single-nucleotide polymorphism | Genomes | Gene mapping | Health risk assessment | Chromosome 17 | Genotypes
Journal Article
by Dunning, A.M and Michailidou, K and Kuchenbaecker, K.B and Thompson, D and French, J.D and Beesley, J and Healey, C.S and Kar, S and Pooley, K.A and Lopez-Knowles, E and Dicks, E and Barrowdale, D and Sinnott-Armstrong, N.A and Sallari, R.C and Hillman, K.M and Kaufmann, S and Sivakumaran, H and Marjaneh, M. Moradi and Lee, J.S and Hills, M and Jarosz, M and ry, S and Canisius, S and Bolla, M.K and Dennis, J and Wang, Q and Hopper, J.L and Southey, M.C and Broeks, A and Schmidt, M.K and Lophatananon, A and Muir, K and Beckmann, M.W and Fasching, P.A and Dos-Santos-Silva, I and Peto, J and Sawyer, E.J and Tomlinson, I and Burwinkel, B and Marme, F and Guenel, P and Truong, T and Bojesen, S.E and Flyger, H and Gonzalez-Neira, A and Perez, J.I and Anton-Culver, H and Eunjung, L and Arndt, V and Brenner, H and Meindl, A and Schmutzler, R.K and Brauch, H and Hamann, U and Aittomaki, K and Blomqvist, C and Ito, H and Matsuo, K and Bogdanova, N and Dork, T and Lindblom, A and Margolin, S and Kosma, V.M and Mannermaa, A and Tseng, C.C and Wu, A.H and Lambrechts, D and Wildiers, H and Chang-Claude, J and Rudolph, A and Peterlongo, P and Radice, P and Olson, J.E and Giles, G.G and Milne, R.L and Haiman, C.A and Henderson, B.E and Goldberg, M.S and Teo, S.H and Yip, C.H and Nord, S and Borresen-Dale, A.L and Kristensen, V and Long, J and Zheng, W and Pylkas, K and Winqvist, R and Anulis, I.L and Knight, J.A and Devilee, P and Seynaeve, C and Figueroa, J and Sherman, M.E and Czene, K and Darabi, H and Hollestelle, A and Ouweland, A.M. van den and Humphreys, K and Gao, Y.T and Shu, X.O and ... and Lund University and Division of Clinical Genetics and Kemisk fysik and Avdelningen för klinisk genetik and BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation and Lunds universitet and Chemical Physics
Nature Genetics, ISSN 1061-4036, 2016, Volume 48, pp. 374 - 386
We analyzed 3,872 common genetic variants across the ESR1 locus (encoding estrogen receptor alpha) in 118,816 subjects from three international consortia. We... 
Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Cancer and Oncology | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article
by Maya Ghoussaini and Juliet D French and Kyriaki Michailidou and Silje Nord and Jonathan Beesley and Sander Canisus and Kristine M Hillman and Susanne Kaufmann and Haran Sivakumaran and Mahdi Moradi Marjaneh and Wei Zheng and Qiuyin Cai and Robert Winqvist and Katri Pylkäs and Irene L Andrulis and Peter Devilee and Rob AEM Tollenaar and Montserrat García-Closas and Jonine Figueroa and Per Hall and Daehee Kang and Kamila Czene and Judith S Brand and Hatef Darabi and Mikael Eriksson and Maartje J Hooning and Linetta B Koppert and Jingmei Li and Xiao-Ou Shu and Ying Zheng and Angela Cox and Mikael Hartman and Simon S Cross and Mitul Shah and Valerie Rhenius and Ji-Yeob Choi and Kee Seng Chia and Maria Kabisch and Diana Torres and Craig Luccarini and Don M Conroy and Anna Jakubowska and Jan Lubinski and Suleeporn Sangrajrang and Jason S Lee and Paul Brennan and Curtis Olswold and Susan Slager and Chen-Yang Shen and Ming-Feng Hou and Anthony Swerdlow and Minouk J Schoemaker and Jacques Simard and Paul DP Pharoah and Vessela Kristensen and Joe Dennis and Georgia Chenevix-Trench and Douglas F Easton and Alison M Dunning and Stacey L Edwards and Manjeet K Bolla and Qin Wang and Ed Dicks and Roger L Milne and John L Hopper and Melissa C Southey and Marjanka K Schmidt and Annegien Broeks and Kenneth Muir and Artitaya Lophatananon and Peter A Fasching and Matthias W Beckmann and Olivia Fletcher and Nichola Johnson and Elinor J Sawyer and Ian Tomlinson and Barbara Burwinkel and Frederik Marme and Pascal Guénel and Thérèse Truong and Stig E Bojesen and Henrik Flyger and Javier Benitez and Anna González-Neira and M Rosario Alonso and Guillermo Pita and Susan L Neuhausen and Hoda Anton-Culver and Hermann Brenner and Volker Arndt and Alfons Meindl and Rita K Schmutzler and Hiltrud Brauch and Ute Hamann and Daniel C Tessier and Daniel Vincent and Heli Nevanlinna and Sofia Khan and Keitaro Matsuo and Hidemi Ito and ...
American Journal of Human Genetics, ISSN 0002-9297, 10/2016, Volume 99, Issue 4, p. 903
  Genome-wide association studies (GWASs) have revealed increased breast cancer risk associated with multiple genetic variants at 5p12. Here, we report the... 
Proteins | Genetics | Breast cancer | Genomes | Gene expression
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e20711
Journal Article
Nature Genetics, ISSN 1061-4036, 04/2016, Volume 48, Issue 4, pp. 374 - +
We analyzed 3,872 common genetic variants across the ESR1 locus (encoding estrogen receptor a) in 118,816 subjects from three international consortia. We found... 
BRCA2 MUTATION CARRIERS | MAMMOGRAPHIC DENSITY | METAANALYSIS | BONE-MINERAL DENSITY | MODIFIERS | DISEASE | SUSCEPTIBILITY LOCUS | EXPRESSION | GENOME-WIDE ASSOCIATION | REVEALS
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 08/2017, Volume 101, Issue 2, pp. 255 - 266
Journal Article
by Ghoussaini, Maya and French, Juliet D and Michailidou, Kyriaki and Nord, Silje and Beesley, Jonathan and Canisus, Sander and Hillman, Kristine M and Kaufmann, Susanne and Sivakumaran, Haran and Moradi Marjaneh, Mahdi and Lee, Jason S and Dennis, Joe and Bolla, Manjeet K and Wang, Qin and Dicks, Ed and Milne, Roger L and Hopper, John L and Southey, Melissa C and Schmidt, Marjanka K and Broeks, Annegien and Muir, Kenneth and Lophatananon, Artitaya and Fasching, Peter A and Beckmann, Matthias W and Fletcher, Olivia and Johnson, Nichola and Sawyer, Elinor J and Tomlinson, Ian and Burwinkel, Barbara and Marme, Frederik and Guénel, Pascal and Truong, Thérèse and Bojesen, Stig E and Flyger, Henrik and Benitez, Javier and González-Neira, Anna and Alonso, M. Rosario and Pita, Guillermo and Neuhausen, Susan L and Anton-Culver, Hoda and Brenner, Hermann and Arndt, Volker and Meindl, Alfons and Schmutzler, Rita K and Brauch, Hiltrud and Hamann, Ute and Tessier, Daniel C and Vincent, Daniel and Nevanlinna, Heli and Khan, Sofia and Matsuo, Keitaro and Ito, Hidemi and Dörk, Thilo and Bogdanova, Natalia V and Lindblom, Annika and Margolin, Sara and Mannermaa, Arto and Kosma, Veli-Matti and Wu, Anna H and Van Den Berg, David and Lambrechts, Diether and Floris, Giuseppe and Chang-Claude, Jenny and Rudolph, Anja and Radice, Paolo and Barile, Monica and Couch, Fergus J and Hallberg, Emily and Giles, Graham G and Haiman, Christopher A and Le Marchand, Loic and Goldberg, Mark S and Teo, Soo H and Yip, Cheng Har and Borresen-Dale, Anne-Lise and Zheng, Wei and Zheng, Ying and Cai, Qiuyin and Winqvist, Robert and Pylkäs, Katri and Andrulis, Irene L and Devilee, Peter and Tollenaar, Rob A.E.M and García-Closas, Montserrat and Figueroa, Jonine and Hall, Per and Czene, Kamila and Brand, Judith S and Darabi, Hatef and Eriksson, Mikael and Hooning, Maartje J and Koppert, Linetta B and Li, Jingmei and Shu, Xiao-Ou and Cox, Angela and Cross, Simon S and Shah, Mitul and Rhenius, Valerie and Choi, Ji-Yeob and Kang, Daehee and ... and kConFab AOCS and NBCS Collaborators and kConFab/AOCS Investigators
The American Journal of Human Genetics, ISSN 0002-9297, 10/2016, Volume 99, Issue 4, pp. 903 - 911
Journal Article
Journal of Isfahan Medical School, ISSN 1027-7595, 10/2017, Volume 35, Issue 441, pp. 969 - 977
Journal Article