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CLINICAL CANCER RESEARCH, ISSN 1078-0432, 05/2019, Volume 25, Issue 10, pp. 3190 - 3190
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 02/2019, Volume 25, Issue 4, pp. 1136 - 1138
The concept of complete molecular profiling to select investigational treatment options is appealing, theoretically allowing the matching of patients to... 
ONCOLOGY
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 11/2018, Volume 36, Issue 31, pp. 3074 - 3076
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 09/2019, Volume 106, Issue 3, pp. 498 - 500
Journal Article
Nature reviews. Clinical oncology, ISSN 1759-4774, 2014, Volume 11, Issue 9, pp. 503 - 504
Cytotoxic agents are conventionally dosed on the basis of the maximum tolerated dose defined in phase I trials. A study assessing adverse events in over 2,000... 
ONCOLOGY | INHIBITOR | CANCER | Antineoplastic Agents - adverse effects | Humans | Antineoplastic Agents - pharmacokinetics | Drug Approval | Antineoplastic Agents - administration & dosage | Molecular Targeted Therapy | Research Design | Clinical Trials, Phase I as Topic | Clinical Trials, Phase II as Topic
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 12/2019, Volume 84, Issue 6, pp. 1153 - 1155
The population pharmacokinetics of atezolizumab demonstrate that the trough concentrations are well above the putative target of 6 µg/ml. Thus, alternative... 
Medicine & Public Health | Schedule | Pharmacoeconomics | Oncology | Cancer Research | Pharmacology/Toxicology | Pharmacokinetics | Atezolizumab | Medical policy | Public health | Dosing | Schedules | Chemotherapy | Index Medicus
Journal Article
NATURE REVIEWS CLINICAL ONCOLOGY, ISSN 1759-4774, 03/2015, Volume 12, Issue 3, pp. 126 - 126
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 12/2019, Volume 59, Issue 12, pp. 1632 - 1640
This study investigated the time course and magnitude of the pharmacokinetic interaction between capecitabine and the cytochrome P450 (CYP) 2C9 substrate... 
pharmacokinetics | capecitabine | CYP2C9 | celecoxib | drug‐drug interaction | Cytochrome | Plasma | Warfarin | Cytochrome P450 | Drug interactions | Pharmacology | Exposure | Celecoxib | Substrates | Confidence intervals | Equivalence | Drug interaction | Cytochromes P450 | Index Medicus
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 10/2011, Volume 103, Issue 20, p. 1488
Feuerstein and Ratain suggest these trends reflect investors' perceptions of these companies, as indicated by market capitalization. At 120 days before the... 
Stock prices | Investors | Oncology | Capitalization
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 11/2019, Volume 106, Issue 5, pp. 914 - 915
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2010, Volume 363, Issue 18, pp. 1693 - 1703
A small group of patients with non–small-cell lung cancer have genetic lesions that activate anaplastic lymphoma kinase (ALK). Crizotinib, an orally... 
ALK | MEDICINE, GENERAL & INTERNAL | GEFITINIB | EML4-ALK FUSION GENE | 2ND-LINE TREATMENT | PHASE-II | IDENTIFICATION | TUMORS | ACTIVATING MUTATIONS | EGFR | CHEMOTHERAPY | Lung Neoplasms - drug therapy | Pyrazoles - therapeutic use | Microtubule-Associated Proteins - genetics | Humans | Middle Aged | Receptors, Growth Factor - antagonists & inhibitors | Lung Neoplasms - pathology | Male | Protein Kinase Inhibitors - adverse effects | Protein-Tyrosine Kinases - genetics | Pyridines - adverse effects | Serine Endopeptidases - genetics | Cell Cycle Proteins - genetics | Adult | Female | Pyrazoles - adverse effects | Pyridines - therapeutic use | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Pyridines - administration & dosage | Administration, Oral | Carcinoma, Non-Small-Cell Lung - genetics | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Kaplan-Meier Estimate | In Situ Hybridization, Fluorescence | Receptor Protein-Tyrosine Kinases | Disease Progression | Protein Kinase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Oncogene Proteins, Fusion - genetics | Protein Kinase Inhibitors - therapeutic use | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Protein-Tyrosine Kinases - antagonists & inhibitors | Tyrosine | Care and treatment | Lung cancer, Small cell | Genetic aspects | Diagnosis | Health aspects | Phosphotransferases | Lymphomas | Pharmaceutical industry | Lung cancer | Tumors
Journal Article
Nature Reviews Cancer, ISSN 1474-175X, 05/2006, Volume 6, Issue 5, pp. 409 - 414
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 10/2015, Volume 107, Issue 10, p. 1
  Clinically annotated specimens from cancer clinical trial participants offer an opportunity for discovery and validation of pharmacogenomic findings. The... 
Genomics | Leukemia | Clinical trials | Pharmacology | Multivariate analysis | Optimization | Cancer
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 12/2018
The concept of complete molecular profiling to select investigational treatment options is appealing, theoretically allowing the matching of patients to... 
Journal Article