Journal of the American Society of Hypertension, ISSN 1933-1711, 2014, Volume 8, Issue 6, pp. 368 - 375
Abstract MicroRNAs (miRs), as essential gene expression regulators, modulate cardiovascular development and disease and thus they are emerging as potential...
Cardiovascular | essential hypertension | pulse pressure | left ventricular mass index | MicroRNAs | MANAGEMENT | HEART-FAILURE | MECHANISMS | LEFT-VENTRICULAR HYPERTROPHY | BLOOD-PRESSURE | MIR-126 | MIRNA | CARDIAC-HYPERTROPHY | DISEASE | PERIPHERAL VASCULAR DISEASE | CARDIOVASCULAR RISK | Follow-Up Studies | Humans | Middle Aged | Gene Expression Regulation | Male | MicroRNAs - biosynthesis | Hypertension - physiopathology | Hypertension - metabolism | RNA - genetics | Female | Blood Pressure - physiology | MicroRNAs - genetics | Hypertension - genetics | Essential Hypertension | Real-Time Polymerase Chain Reaction
Cardiovascular | essential hypertension | pulse pressure | left ventricular mass index | MicroRNAs | MANAGEMENT | HEART-FAILURE | MECHANISMS | LEFT-VENTRICULAR HYPERTROPHY | BLOOD-PRESSURE | MIR-126 | MIRNA | CARDIAC-HYPERTROPHY | DISEASE | PERIPHERAL VASCULAR DISEASE | CARDIOVASCULAR RISK | Follow-Up Studies | Humans | Middle Aged | Gene Expression Regulation | Male | MicroRNAs - biosynthesis | Hypertension - physiopathology | Hypertension - metabolism | RNA - genetics | Female | Blood Pressure - physiology | MicroRNAs - genetics | Hypertension - genetics | Essential Hypertension | Real-Time Polymerase Chain Reaction
Journal Article
Journal of the American Society of Hypertension, ISSN 1933-1711, 2015, Volume 9, Issue 10, pp. 802 - 810
Abstract MicroRNAs regulate several aspects of physiological and pathologic cardiac hypertrophy, and they represent promising therapeutic targets in...
Cardiovascular | miR-499 | miR-208b | Left ventricular mass index | miR-1 | miR-133a | miR-26b | miR-21 | DIFFERENTIAL EXPRESSION | MARKERS | RISK | PREVALENCE | DAMAGE | FAMILY | MASS | PERIPHERAL VASCULAR DISEASE | Leukocytes, Mononuclear - metabolism | Hypertrophy, Left Ventricular - blood | Humans | Hypertrophy, Left Ventricular - etiology | Middle Aged | Male | Gene Expression Profiling | Biomarkers - blood | Reverse Transcriptase Polymerase Chain Reaction | Hypertension - blood | Ultrasonography | Hypertension - complications | Female | Aged | MicroRNAs - blood | Essential Hypertension | Hypertrophy, Left Ventricular - diagnostic imaging
Cardiovascular | miR-499 | miR-208b | Left ventricular mass index | miR-1 | miR-133a | miR-26b | miR-21 | DIFFERENTIAL EXPRESSION | MARKERS | RISK | PREVALENCE | DAMAGE | FAMILY | MASS | PERIPHERAL VASCULAR DISEASE | Leukocytes, Mononuclear - metabolism | Hypertrophy, Left Ventricular - blood | Humans | Hypertrophy, Left Ventricular - etiology | Middle Aged | Male | Gene Expression Profiling | Biomarkers - blood | Reverse Transcriptase Polymerase Chain Reaction | Hypertension - blood | Ultrasonography | Hypertension - complications | Female | Aged | MicroRNAs - blood | Essential Hypertension | Hypertrophy, Left Ventricular - diagnostic imaging
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2011, Volume 107, Issue 1, pp. 59 - 63
Monocyte chemoattractant protein-1 (MCP-1) and peroxisome proliferator-activated receptor-γ (PPAR-γ) play a significant role in monocyte activation, vascular...
Cardiovascular | ADHESION | CARDIAC & CARDIOVASCULAR SYSTEMS | MACROPHAGES | ARTERIAL-HYPERTENSION | ATHEROSCLEROSIS | PPAR-GAMMA | ALPHA | TYPE-1 RECEPTOR | BLOCKADE | ANGIOTENSIN | PROGRESSION | Severity of Illness Index | Antihypertensive Agents - pharmacology | Benzoates - therapeutic use | Gene Expression - drug effects | Humans | Middle Aged | Chemokine CCL2 - genetics | Hypertension - drug therapy | Male | Antihypertensive Agents - therapeutic use | Amlodipine - therapeutic use | Monocytes - drug effects | Amlodipine - pharmacology | Benzoates - pharmacology | Benzimidazoles - pharmacology | Female | Chemokine CCL2 - drug effects | Benzimidazoles - therapeutic use | PPAR gamma - genetics | Hypertension | Amlodipine | Care and treatment | Gene expression | Angiotensin
Cardiovascular | ADHESION | CARDIAC & CARDIOVASCULAR SYSTEMS | MACROPHAGES | ARTERIAL-HYPERTENSION | ATHEROSCLEROSIS | PPAR-GAMMA | ALPHA | TYPE-1 RECEPTOR | BLOCKADE | ANGIOTENSIN | PROGRESSION | Severity of Illness Index | Antihypertensive Agents - pharmacology | Benzoates - therapeutic use | Gene Expression - drug effects | Humans | Middle Aged | Chemokine CCL2 - genetics | Hypertension - drug therapy | Male | Antihypertensive Agents - therapeutic use | Amlodipine - therapeutic use | Monocytes - drug effects | Amlodipine - pharmacology | Benzoates - pharmacology | Benzimidazoles - pharmacology | Female | Chemokine CCL2 - drug effects | Benzimidazoles - therapeutic use | PPAR gamma - genetics | Hypertension | Amlodipine | Care and treatment | Gene expression | Angiotensin
Journal Article
American Journal of Cardiology, The, ISSN 0002-9149, 2007, Volume 99, Issue 12, pp. 1721 - 1725
The appropriate treatment for the restoration of sinus rhythm in patients with atrial fibrillation (AF) of recent onset is still the subject of controversy. In...
Cardiovascular | CARDIOVERSION | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | THERAPY | DRUGS | SINUS RHYTHM | Single-Blind Method | Injections, Intravenous | Prospective Studies | Atrial Fibrillation - drug therapy | Procainamide - administration & dosage | Humans | Middle Aged | Propafenone - adverse effects | Male | Anti-Arrhythmia Agents - therapeutic use | Anti-Arrhythmia Agents - administration & dosage | Procainamide - therapeutic use | Procainamide - adverse effects | Amiodarone - administration & dosage | Amiodarone - adverse effects | Amiodarone - therapeutic use | Anti-Arrhythmia Agents - adverse effects | Aged, 80 and over | Adult | Female | Propafenone - administration & dosage | Aged | Propafenone - therapeutic use
Cardiovascular | CARDIOVERSION | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | THERAPY | DRUGS | SINUS RHYTHM | Single-Blind Method | Injections, Intravenous | Prospective Studies | Atrial Fibrillation - drug therapy | Procainamide - administration & dosage | Humans | Middle Aged | Propafenone - adverse effects | Male | Anti-Arrhythmia Agents - therapeutic use | Anti-Arrhythmia Agents - administration & dosage | Procainamide - therapeutic use | Procainamide - adverse effects | Amiodarone - administration & dosage | Amiodarone - adverse effects | Amiodarone - therapeutic use | Anti-Arrhythmia Agents - adverse effects | Aged, 80 and over | Adult | Female | Propafenone - administration & dosage | Aged | Propafenone - therapeutic use
Journal Article
Journal of the American Society of Hypertension, ISSN 1933-1711, 2013, Volume 7, Issue 4, pp. 276 - 282
Abstract Background Hypertensive populations suffer from an increased susceptibility to ventricular arrhythmias and sudden cardiac death. A high-salt diet...
Cardiovascular | urinary sodium | Essential hypertension | urinary potassium | ventricular arrhythmias | ADULTS | PREVENTION | EXCRETION | BLOOD-PRESSURE | SALT | INDIVIDUALS | HYPERTROPHY | DIETARY-SODIUM | DISEASE | PERIPHERAL VASCULAR DISEASE | 24-H URINARY SODIUM | Severity of Illness Index | Humans | Middle Aged | Potassium, Dietary - urine | Sodium, Dietary - urine | Male | Ventricular Premature Complexes - metabolism | Hypertension - metabolism | Ventricular Premature Complexes - diet therapy | Diet, Sodium-Restricted | Ventricular Premature Complexes - diagnosis | Female | Aged | Blood Pressure - physiology | Hypertension - diet therapy | Electrocardiography, Ambulatory
Cardiovascular | urinary sodium | Essential hypertension | urinary potassium | ventricular arrhythmias | ADULTS | PREVENTION | EXCRETION | BLOOD-PRESSURE | SALT | INDIVIDUALS | HYPERTROPHY | DIETARY-SODIUM | DISEASE | PERIPHERAL VASCULAR DISEASE | 24-H URINARY SODIUM | Severity of Illness Index | Humans | Middle Aged | Potassium, Dietary - urine | Sodium, Dietary - urine | Male | Ventricular Premature Complexes - metabolism | Hypertension - metabolism | Ventricular Premature Complexes - diet therapy | Diet, Sodium-Restricted | Ventricular Premature Complexes - diagnosis | Female | Aged | Blood Pressure - physiology | Hypertension - diet therapy | Electrocardiography, Ambulatory
Journal Article
Pacing and Clinical Electrophysiology, ISSN 0147-8389, 11/2000, Volume 23, Issue 11P2, pp. 1883 - 1887
This randomized study compared the efficacy and safety of amiodarone, propafenone and sotalol in the prevention of atrial fibrillation. Methods: The population...
atrial fibrillation | amiodarone | sinus rhythm maintenance | propafenone | sotalol | MAINTENANCE | CARDIAC & CARDIOVASCULAR SYSTEMS | THERAPY | ENGINEERING, BIOMEDICAL | LOW-DOSE AMIODARONE | SUPPRESSION | Recurrence | Administration, Oral | Humans | Middle Aged | Propafenone - adverse effects | Risk Factors | Male | Treatment Outcome | Anti-Arrhythmia Agents - administration & dosage | Amiodarone - administration & dosage | Sotalol - administration & dosage | Amiodarone - adverse effects | Heart Rate - drug effects | Sotalol - adverse effects | Female | Propafenone - administration & dosage | Aged | Atrial Fibrillation - prevention & control | Amiodarone | Propafenone | Atrial fibrillation | Sinus rhythm maintenance | Sotalol
atrial fibrillation | amiodarone | sinus rhythm maintenance | propafenone | sotalol | MAINTENANCE | CARDIAC & CARDIOVASCULAR SYSTEMS | THERAPY | ENGINEERING, BIOMEDICAL | LOW-DOSE AMIODARONE | SUPPRESSION | Recurrence | Administration, Oral | Humans | Middle Aged | Propafenone - adverse effects | Risk Factors | Male | Treatment Outcome | Anti-Arrhythmia Agents - administration & dosage | Amiodarone - administration & dosage | Sotalol - administration & dosage | Amiodarone - adverse effects | Heart Rate - drug effects | Sotalol - adverse effects | Female | Propafenone - administration & dosage | Aged | Atrial Fibrillation - prevention & control | Amiodarone | Propafenone | Atrial fibrillation | Sinus rhythm maintenance | Sotalol
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 02/2010, Volume 285, Issue 8, pp. 5555 - 5568
The angiotensin converting enzyme (ACE) catalyzes the extracellular formation of angiotensin II, and degradation of bradykinin, thus regulating blood pressure...
PATHWAYS | DOMAIN | ACE | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITORS | RECEPTORS | PROTEINS | PLASMA-MEMBRANE | EXPRESSION | CANCER | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Transcription, Genetic - drug effects | Active Transport, Cell Nucleus - physiology | Humans | Lysosomes - enzymology | Cell Nucleus - enzymology | Peptidyl-Dipeptidase A - metabolism | Focal Adhesion Kinase 1 - metabolism | Myocytes, Smooth Muscle - cytology | Receptor, Platelet-Derived Growth Factor beta - metabolism | Cell Line | Myocytes, Smooth Muscle - enzymology | Rats | Enzyme Activation - drug effects | Transcription, Genetic - physiology | Animals | Peptidyl-Dipeptidase A - pharmacology | Signal Transduction - drug effects | Endothelial Cells - cytology | Active Transport, Cell Nucleus - drug effects | Signal Transduction - physiology | Endosomes - enzymology | Muscle, Smooth - cytology | Endothelial Cells - enzymology | Enzyme Activation - physiology | Muscle, Smooth - enzymology | Nucleus | Endocytosis | Receptors | Trafficking | Intracellular Trafficking | Cell | Protein | Cell Biology | Sorting
PATHWAYS | DOMAIN | ACE | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INHIBITORS | RECEPTORS | PROTEINS | PLASMA-MEMBRANE | EXPRESSION | CANCER | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Transcription, Genetic - drug effects | Active Transport, Cell Nucleus - physiology | Humans | Lysosomes - enzymology | Cell Nucleus - enzymology | Peptidyl-Dipeptidase A - metabolism | Focal Adhesion Kinase 1 - metabolism | Myocytes, Smooth Muscle - cytology | Receptor, Platelet-Derived Growth Factor beta - metabolism | Cell Line | Myocytes, Smooth Muscle - enzymology | Rats | Enzyme Activation - drug effects | Transcription, Genetic - physiology | Animals | Peptidyl-Dipeptidase A - pharmacology | Signal Transduction - drug effects | Endothelial Cells - cytology | Active Transport, Cell Nucleus - drug effects | Signal Transduction - physiology | Endosomes - enzymology | Muscle, Smooth - cytology | Endothelial Cells - enzymology | Enzyme Activation - physiology | Muscle, Smooth - enzymology | Nucleus | Endocytosis | Receptors | Trafficking | Intracellular Trafficking | Cell | Protein | Cell Biology | Sorting
Journal Article
Heart Failure Reviews, ISSN 1382-4147, 3/2019, Volume 24, Issue 2, pp. 219 - 226
Obesity is a major risk factor for the development of chronic heart failure (CHF) and does not only pose diagnostic challenges, but also has prognostic...
Heart failure | Obesity | Body mass index | Medicine & Public Health | Cardiology | Natriuretic peptides | NEPRILYSIN INHIBITION | CARDIAC & CARDIOVASCULAR SYSTEMS | ATRIAL | TISSUE | BODY-COMPOSITION | INSULIN SENSITIVITY | NORMAL-WEIGHT | ADIPONECTIN | CARDIOVASCULAR-DISEASE | PLASMA-LEVEL | BROWN | Medical colleges | Cardiac patients | Risk factors | Brain natriuretic peptide | Phenotypes | Adipose tissue | Fat metabolism | Body fat | Benign | Beta blockers | Heart diseases
Heart failure | Obesity | Body mass index | Medicine & Public Health | Cardiology | Natriuretic peptides | NEPRILYSIN INHIBITION | CARDIAC & CARDIOVASCULAR SYSTEMS | ATRIAL | TISSUE | BODY-COMPOSITION | INSULIN SENSITIVITY | NORMAL-WEIGHT | ADIPONECTIN | CARDIOVASCULAR-DISEASE | PLASMA-LEVEL | BROWN | Medical colleges | Cardiac patients | Risk factors | Brain natriuretic peptide | Phenotypes | Adipose tissue | Fat metabolism | Body fat | Benign | Beta blockers | Heart diseases
Journal Article
JOURNAL OF HUMAN HYPERTENSION, ISSN 0950-9240, 07/2019, Volume 33, Issue 7, pp. 491 - 498
The effects of systemic hypertension on left ventricular function have been well described, as has been the response of the resulting alterations to...
GLOBAL LONGITUDINAL STRAIN | HYPERTROPHY | PROGNOSTIC IMPORTANCE | EJECTION FRACTION | HEART-FAILURE | DISEASE | PERIPHERAL VASCULAR DISEASE | SYSTEMIC HYPERTENSION | ECHOCARDIOGRAPHY | EUROPEAN ASSOCIATION | AMERICAN SOCIETY | Hypertension | Complications and side effects | Cardiovascular diseases | Risk factors | Heart | Echocardiography | Magnetic resonance imaging | Clinical trials | Ventricle | Structure-function relationships
GLOBAL LONGITUDINAL STRAIN | HYPERTROPHY | PROGNOSTIC IMPORTANCE | EJECTION FRACTION | HEART-FAILURE | DISEASE | PERIPHERAL VASCULAR DISEASE | SYSTEMIC HYPERTENSION | ECHOCARDIOGRAPHY | EUROPEAN ASSOCIATION | AMERICAN SOCIETY | Hypertension | Complications and side effects | Cardiovascular diseases | Risk factors | Heart | Echocardiography | Magnetic resonance imaging | Clinical trials | Ventricle | Structure-function relationships
Journal Article
Current Hypertension Reports, ISSN 1522-6417, 12/2012, Volume 14, Issue 6, pp. 581 - 590
Systemic hypertension has been linked to a wide range of major eye diseases. High arterial blood pressure (BP) decreases choroidal circulatory flow, increases...
Hypertension | Nephrology | Eye disease | Hypertensive retinopathy | Medicine & Public Health | Hypertensive choroidopathy | Metabolic Diseases | Cardiovascular risk | General Practice / Family Medicine | Internal Medicine | Primary Care Medicine | Cardiology | RISK-FACTORS | VASCULAR CALIBER | SYSTEMIC HYPERTENSION | VEIN OCCLUSION | RETINAL MICROVASCULAR ABNORMALITIES | BLOOD-PRESSURE | ATHEROSCLEROSIS-RISK | OPEN-ANGLE GLAUCOMA | JAPANESE POPULATION | OCULAR PERFUSION-PRESSURE | PERIPHERAL VASCULAR DISEASE | Hypertension - complications | Hypertensive Retinopathy - etiology | Humans | Risk Factors | Eye Diseases - etiology
Hypertension | Nephrology | Eye disease | Hypertensive retinopathy | Medicine & Public Health | Hypertensive choroidopathy | Metabolic Diseases | Cardiovascular risk | General Practice / Family Medicine | Internal Medicine | Primary Care Medicine | Cardiology | RISK-FACTORS | VASCULAR CALIBER | SYSTEMIC HYPERTENSION | VEIN OCCLUSION | RETINAL MICROVASCULAR ABNORMALITIES | BLOOD-PRESSURE | ATHEROSCLEROSIS-RISK | OPEN-ANGLE GLAUCOMA | JAPANESE POPULATION | OCULAR PERFUSION-PRESSURE | PERIPHERAL VASCULAR DISEASE | Hypertension - complications | Hypertensive Retinopathy - etiology | Humans | Risk Factors | Eye Diseases - etiology
Journal Article
Cardiovascular Drugs and Therapy, ISSN 0920-3206, 3/1998, Volume 12, Issue 1, pp. 47 - 55
We evaluated the effects of long-term digoxin therapy on exercise capacity and on physiological parameters reflecting autonomic tone in 23 patients with mild...
baroreceptor sensitivity | digoxin | Medicine & Public Health | Cardiology | cardiopulmonary exercise testing | heart rate variability | Baroreceptor sensitivity | Cardiopulmonary exercise testing | Digoxin | Heart rate variability | CORONARY-ARTERY DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | POWER SPECTRUM ANALYSIS | AUTONOMIC FUNCTION | PERFORMANCE | ANAEROBIC THRESHOLD | MILD | TRIAL | RESPONSES | END-POINT | PHARMACOLOGY & PHARMACY | LEFT-VENTRICULAR FUNCTION | Cardiotonic Agents - therapeutic use | Heart Rate - drug effects | Exercise Test | Humans | Middle Aged | Female | Male | Aged | Heart Diseases - drug therapy | Digoxin - therapeutic use | Exercise Tolerance - drug effects | Pressoreceptors - drug effects | Heart failure | Physiological aspects | Care and treatment | Cardiac patients
baroreceptor sensitivity | digoxin | Medicine & Public Health | Cardiology | cardiopulmonary exercise testing | heart rate variability | Baroreceptor sensitivity | Cardiopulmonary exercise testing | Digoxin | Heart rate variability | CORONARY-ARTERY DISEASE | CARDIAC & CARDIOVASCULAR SYSTEMS | POWER SPECTRUM ANALYSIS | AUTONOMIC FUNCTION | PERFORMANCE | ANAEROBIC THRESHOLD | MILD | TRIAL | RESPONSES | END-POINT | PHARMACOLOGY & PHARMACY | LEFT-VENTRICULAR FUNCTION | Cardiotonic Agents - therapeutic use | Heart Rate - drug effects | Exercise Test | Humans | Middle Aged | Female | Male | Aged | Heart Diseases - drug therapy | Digoxin - therapeutic use | Exercise Tolerance - drug effects | Pressoreceptors - drug effects | Heart failure | Physiological aspects | Care and treatment | Cardiac patients
Journal Article
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Full Text
Differential Metabolic Effects of Beta-Blockers: an Updated Systematic Review of Nebivolol
Current Hypertension Reports, ISSN 1522-6417, 3/2017, Volume 19, Issue 3, pp. 1 - 10
Blood pressure management in hypertensive patients with metabolic abnormalities is challenging, since many of the antihypertensive drugs adversely affect...
Hypertension | Nebivolol | Obesity | Nephrology | Medicine & Public Health | Insulin sensitivity | Metabolic Diseases | General Practice / Family Medicine | Internal Medicine | Primary Care Medicine | Lipid metabolism | Cardiology | OXIDATIVE STRESS | ENDOTHELIAL DYSFUNCTION | ANTIHYPERTENSIVE DRUGS | BLOOD-PRESSURE | HYPERTENSIVE PATIENTS | INSULIN-RESISTANCE | ARTERIAL STIFFNESS | NITRIC-OXIDE | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | TYPE-2 DIABETES-MELLITUS | Glucose metabolism | Diabetics | Vasodilators | Analysis | Nitric oxide | Antihypertensive drugs | Insulin resistance | Insulin
Hypertension | Nebivolol | Obesity | Nephrology | Medicine & Public Health | Insulin sensitivity | Metabolic Diseases | General Practice / Family Medicine | Internal Medicine | Primary Care Medicine | Lipid metabolism | Cardiology | OXIDATIVE STRESS | ENDOTHELIAL DYSFUNCTION | ANTIHYPERTENSIVE DRUGS | BLOOD-PRESSURE | HYPERTENSIVE PATIENTS | INSULIN-RESISTANCE | ARTERIAL STIFFNESS | NITRIC-OXIDE | CARDIOVASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | TYPE-2 DIABETES-MELLITUS | Glucose metabolism | Diabetics | Vasodilators | Analysis | Nitric oxide | Antihypertensive drugs | Insulin resistance | Insulin
Journal Article
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