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European Journal of Immunology, ISSN 0014-2980, 01/2013, Volume 43, Issue 1, pp. 281 - 289
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 11/2016, Volume 7, p. 543
IL-1 beta plays a crucial role in the differentiation of human Th17 cells. We report here that IL-1R1 expression is significantly increased in both naive and... 
Multiple sclerosis | IL-1R | IL-1 | IRF4 | Th17 cells | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | TGF-BETA | ROR-GAMMA-T | multiple sclerosis | RECEPTOR | INDUCTION | IMMUNOLOGY | T-HELPER-CELLS | GROWTH-FACTOR-BETA | T(H)17 | TRANSCRIPTION FACTOR | EXPRESSION | Care and treatment | Relapse | Analysis | Interferon | Research | Cell differentiation | Gene expression | Properties | Diseases | Multiple Sclerosis | Th17 Cells
Journal Article
Journal Article
Journal of Neuroimmunology, ISSN 0165-5728, 2016, Volume 298, pp. 181 - 188
Abstract We report that B cells from pat i e nts with RRMS have decreased endogenous IFN-β secretion and deficient IFN receptor (IFNAR)1/2 and TLR7 gene... 
Neurology | Allergy and Immunology | TLR9 | Multiple sclerosis | TLR7 | IFN-β-1a | B cells | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | DENDRITIC CELLS | IMMUNOLOGY | NEUROSCIENCES | RESPONSES | IFN-beta-1a | IN-VIVO | DISEASE | MICE | EXPRESSION | T-CELLS | INNATE IMMUNITY | LYMPHOCYTES | Methylprednisolone - therapeutic use | Humans | Male | Case-Control Studies | Toll-Like Receptor 9 - agonists | Interferon-beta - therapeutic use | STAT1 Transcription Factor - metabolism | Interferon-beta - genetics | Female | Cytokines - genetics | B-Lymphocytes - metabolism | Guanosine - analogs & derivatives | Multiple Sclerosis, Relapsing-Remitting - pathology | Toll-Like Receptor 7 - agonists | Multiple Sclerosis, Relapsing-Remitting - immunology | Cytokines - metabolism | Multiple Sclerosis, Relapsing-Remitting - drug therapy | Toll-Like Receptor 7 - deficiency | Toll-Like Receptor 9 - drug effects | Interferon Regulatory Factor-7 - metabolism | Drug Synergism | B-Lymphocytes - drug effects | Interferon-beta - metabolism | Glatiramer Acetate - therapeutic use | Guanosine - pharmacology | Tetraspanin-29 - metabolism | Myeloid Differentiation Factor 88 - metabolism | Immunologic Factors - pharmacology | CD4 Antigens - metabolism | Immunologic Factors - therapeutic use | Somatotropin | Care and treatment | Relapse | Analysis | Interferon | Biological response modifiers | Gene expression | Diseases
Journal Article
Journal of Immunology, ISSN 0022-1767, 12/2013, Volume 191, Issue 12, pp. 5867 - 5874
Journal Article
Journal of Immunology, ISSN 0022-1767, 10/2009, Volume 183, Issue 8, pp. 5418 - 5427
IFN-beta-1a has been used over the past 15 years as a primary therapy for relapsing-remitting multiple sclerosis (MS). However, the immunomodulatory mechanisms... 
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | GROWTH-FACTOR-BETA | T(H)17 CELLS | MULTIPLE-SCLEROSIS | DENDRITIC CELLS | MESSENGER-RNA EXPRESSION | CENTRAL-NERVOUS-SYSTEM | INTERFERON-BETA | IMMUNOLOGY | UP-REGULATION | T-CELLS | Receptors, CCR6 - immunology | Interleukin-12 Subunit p35 - metabolism | Interleukin-23 Subunit p19 - antagonists & inhibitors | Dendritic Cells - immunology | Humans | Receptors, CCR6 - antagonists & inhibitors | CD4-Positive T-Lymphocytes - immunology | Receptors, Interleukin - metabolism | Interleukin-23 Subunit p19 - metabolism | STAT1 Transcription Factor - metabolism | Interleukin-1beta - metabolism | Receptors, Retinoic Acid - immunology | Phosphorylation - immunology | Phosphorylation - drug effects | Receptors, Thyroid Hormone - immunology | Interleukin-1beta - antagonists & inhibitors | Nuclear Receptor Subfamily 1, Group F, Member 3 | Receptors, Interleukin - immunology | Receptors, Interleukin - antagonists & inhibitors | Receptors, Retinoic Acid - metabolism | Cell Differentiation - immunology | Interferon beta-1a | Up-Regulation - immunology | Interleukin-23 Subunit p19 - immunology | STAT3 Transcription Factor - immunology | Interleukin-10 - immunology | Interleukin-17 - immunology | STAT1 Transcription Factor - drug effects | T-Lymphocytes, Helper-Inducer - drug effects | T-Lymphocytes, Helper-Inducer - immunology | Receptors, CCR6 - metabolism | Interleukin-10 - metabolism | Dendritic Cells - drug effects | Interleukin-10 - agonists | STAT3 Transcription Factor - metabolism | Cells, Cultured | Interleukin-1beta - immunology | Interleukin-12 Subunit p35 - agonists | Down-Regulation - drug effects | STAT1 Transcription Factor - immunology | Receptors, Thyroid Hormone - metabolism | Up-Regulation - drug effects | Interferon-beta - pharmacology | Interleukin-12 Subunit p35 - immunology | Cell Differentiation - drug effects | Down-Regulation - immunology | STAT3 Transcription Factor - drug effects | Multiple Sclerosis - immunology | CD4-Positive T-Lymphocytes - drug effects
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2004, Volume 101, Issue 23, pp. 8705 - 8708
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2008, Volume 180, Issue 10, pp. 6988 - 6996
Journal Article
Immunologic Research, ISSN 0257-277X, 7/2008, Volume 41, Issue 3, pp. 165 - 174
Statins’ recently discovered anti-inflammatory effects place them at the forefront of the new therapies for chronic inflammatory and autoimmune diseases. Our... 
Allergology | Multiple sclerosis | Immunology | Medicine & Public Health | Anti-inflammatory and neuroprotective effect | Internal Medicine | Medicine/Public Health, general | Autoimmune response | Statins | Th17 cells | COA REDUCTASE INHIBITOR | DENDRITIC CELLS | multiple sclerosis | INFLAMMATORY ARTHRITIS | ANTIGEN PRESENTATION | IMMUNOLOGY | T-HELPER-CELLS | autoimmune response | MULTIPLE-SCLEROSIS | statins | CENTRAL-NERVOUS-SYSTEM | ANIMAL-MODEL | ANTIINFLAMMATORY ROLE | SIMVASTATIN | anti-inflammatory and neuroprotective effect | Simvastatin - therapeutic use | Humans | Interleukin-17 - immunology | Monocytes - metabolism | Monocytes - immunology | Th2 Cells - immunology | Simvastatin - pharmacology | Th1 Cells - immunology | CD4-Positive T-Lymphocytes - immunology | Membrane Microdomains - immunology | Th1 Cells - metabolism | Autoimmunity - immunology | Cytokines - immunology | Th1 Cells - drug effects | Antigen-Presenting Cells - metabolism | Cytokines - metabolism | CD4-Positive T-Lymphocytes - metabolism | Antigen-Presenting Cells - immunology | Th2 Cells - metabolism | Cell Differentiation - immunology | Interleukin-17 - metabolism | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Multiple Sclerosis - immunology | Membrane Microdomains - pathology | Immunologic Factors - pharmacology | Immunologic Factors - therapeutic use | Multiple Sclerosis - drug therapy | Cytokines | Autoimmune diseases | Inflammatory diseases
Journal Article