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RNA, ISSN 1355-8382, 11/2018, Volume 24, Issue 11, p. 1542
In common with other self-cleaving RNAs, the lead-dependent ribozyme (leadzyme) undergoes dynamic fluctuations to a chemically activated conformation. We... 
Chemical modification | Nuclear magnetic resonance--NMR | Ribose | Leadzyme | Sampling | Ribonucleic acid--RNA | Species | Conformation
Journal Article
Nature, ISSN 0028-0836, 11/2018, Volume 563, Issue 7732, pp. E27 - E27
We wish to correct two mutations in Supplementary Table 4 of this Letter. The NCI-H460 cell line was annotated as being mutant for TP53. NCI-H460 has been... 
Tumor proteins | Tumors
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 4078 - 4078
Journal Article
Journal Article
Nature, ISSN 0028-0836, 04/2015, Volume 520, Issue 7546, pp. 239 - 242
Non-small-cell lung cancer is the leading cause of cancer-related death worldwide(1). Chemotherapies such as the topoisomerase II (TopoII) inhibitor etoposide... 
ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | COMPLEXES | SWI/SNF | GROWTH | GENE-EXPRESSION | ANTAGONISM | MUTATIONS | CANCER | POLYCOMB | MICROARRAY DATA | Polycomb Repressive Complex 2 - antagonists & inhibitors | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Humans | Lung Neoplasms - pathology | Molecular Targeted Therapy | Antineoplastic Agents, Phytogenic - therapeutic use | Nuclear Proteins - genetics | DNA Helicases - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung Neoplasms - enzymology | Carcinoma, Non-Small-Cell Lung - genetics | Genes, erbB-1 - genetics | Etoposide - pharmacology | Etoposide - therapeutic use | Topoisomerase II Inhibitors - pharmacology | Transcription Factors - genetics | Anaphase - drug effects | Enhancer of Zeste Homolog 2 Protein | Topoisomerase II Inhibitors - therapeutic use | Xenograft Model Antitumor Assays | Animals | Cell Line, Tumor | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Antineoplastic Agents, Phytogenic - pharmacology | Cell Cycle - drug effects | Protein research | Care and treatment | Oncology, Experimental | Genetic aspects | Research | Lung cancer, Non-small cell | Drug therapy | Gene expression | Cancer | Proteins | Genes | Lung cancer | Genetic engineering | Mutation | Kinases | Cancer therapies | Deoxyribonucleic acid--DNA | Tumors | Apoptosis | Etoposide | Chemotherapy | EZH2 inhibition | BRG1 | EGFR
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2011, Volume 108, Issue 13, pp. 5449 - 5454
Journal Article
Blood, ISSN 0006-4971, 11/2012, Volume 120, Issue 21, pp. 953 - 953
Abstract Abstract 953 Adoptive T cell therapy has the potential to enhance antitumor immunity and improve vaccine efficacy, of which a key challenge is to... 
Journal Article
Nature Immunology, ISSN 1529-2908, 01/2016, Volume 17, Issue 1, pp. 95 - 103
Journal Article
Journal Article
Molecular Cancer, ISSN 1476-4598, 04/2011, Volume 10, Issue 1, pp. 40 - 40
Journal Article
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 12/2005, Volume 48, Issue 26, pp. 8108 - 8111
Combining molecular dynamics (MD) in a hydrated phospholipid (DOPC) bilayer, a Monte Carlo search, and synthesis of locked nucleotide analogues, we discovered... 
DYNAMICS | CHEMISTRY, MEDICINAL | EXTRACELLULAR LOOPS | ANALOGS | LIGAND RECOGNITION | NUCLEOSIDES | Uridine Diphosphate - analogs & derivatives | Humans | Molecular Conformation | Receptors, Purinergic P2 - metabolism | Models, Molecular | Ligands | Purinergic P2 Receptor Agonists | Tumor Cells, Cultured | Uridine Diphosphate - metabolism
Journal Article
The Journal of investigative dermatology, ISSN 0022-202X, 5/2013, Volume 133, Issue 5, pp. 1286 - 1293
Melanoma is an aggressive cancer that metastasizes rapidly, and is refractory to conventional chemotherapies. Identifying miRNAs that are responsible for this... 
Journal Article
Genes & Development, ISSN 0890-9369, 01/2012, Volume 26, Issue 1, pp. 37 - 42
Polycomb-repressive complex 2 (PRC2) promotes tissue-specific differentiation by depositing trimethylated histone H3 Lys 27 (H3K27me3) epigenetic marks to... 
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2010, Volume 98, Issue 3, p. 758
Journal Article
Cancer Research, ISSN 0008-5472, 01/2012, Volume 72, Issue 1, pp. 315 - 324
Neuroblastoma (NB) is the most common extracranial pediatric solid tumor with an undifferentiated status and generally poor prognosis, but the basis for these... 
Axonogenesis
Journal Article
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