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Diabetes, obesity & metabolism, 09/2019
To assess effects of intensive glucose-control on the risk of major clinical outcomes according to estimated glomerular filtration rate (eGFR) levels in type 2... 
Index Medicus
Journal Article
International journal of obesity (2005), 08/2019
Genome-wide association studies (GWAS) have identified more than 250 loci associated with body mass index (BMI) and obesity. However, post-GWAS functional... 
Index Medicus
Journal Article
Diabetes and Metabolism, ISSN 1262-3636, 2019
Aim: In the D.E.S.I.R. cohort, higher consumption of dairy products was associated with lower incidence of hyperglycaemia, and dihydroceramide concentrations... 
Ceramides | Dairy product intake | General population | Longitudinal study | Dihydroceramides
Journal Article
Diabetes and Metabolism, ISSN 1262-3636, 06/2019
AIM:In the D.E.S.I.R. cohort, higher consumption of dairy products was associated with lower incidence of hyperglycaemia, and dihydroceramide concentrations... 
Life Sciences | Food and Nutrition
Journal Article
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 535
Hyperglycemia can impair tubulo-glomerular balance and cause kidney disease by opening pre-glomerular resistances. Susceptibility to kidney disease is... 
Creatinine | Hyperglycemia | Kidneys | Epidermal growth factor receptors | Diabetes mellitus | Reabsorption | Glucose | Diabetes | Kidney diseases | Glomerular filtration rate
Journal Article
Hypertension (Dallas, Tex. : 1979), 06/2019, Volume 73, Issue 6, pp. 1291 - 1299
The optimal blood pressure (BP) goal in patients with diabetes mellitus remains controversial. We examined whether benefits and risks of intensified... 
Journal Article
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 629
Background: Bedside Blind Bone Biopsy (B4) performed by a diabetologist has been recently shown as a reliable tool to manage antibiotherapy in case of Diabetic... 
Biopsy | Diabetes mellitus | Osteitis | Hemoglobin | Leg ulcers | Diabetes | Bone healing | Bone surgery | Patients | Foot diseases | Feet
Journal Article
Hypertension, ISSN 0194-911X, 06/2019, Volume 73, Issue 6, pp. 1291 - 1299
The optimal blood pressure (BP) goal in patients with diabetes mellitus remains controversial. We examined whether benefits and risks of intensified... 
MORTALITY | METAANALYSIS | DISEASE | PERIPHERAL VASCULAR DISEASE | diabetes mellitus | risk | cardiovascular diseases | adult | HYPERTENSION | humans
Journal Article
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 67
Recently, an increased risk of lower extremity amputation (LEA) was observed with canagliflozin, a SGLT2 inhibitor, in the CANVAS trial although observational... 
Diabetes mellitus | Amputation | Diabetes mellitus (insulin dependent) | Diabetes | Diabetes mellitus (non-insulin dependent) | Reclassification | Contraction | Vasopressin | Glomerular filtration rate
Journal Article
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 431
Diabetic retinopathy (DR) has been linked to lower-extremity artery disease (LEAD), but there remains some uncertainty as whether this association is mediated... 
Diabetic retinopathy | Retinopathy | Diabetes mellitus | Amputation | Blood pressure | Diabetes | Kidney diseases | Cardiovascular diseases | Statistics | Diabetes mellitus (non-insulin dependent) | Risk factors | Smoking
Journal Article
Diabetologia, ISSN 0012-186X, 2019, Volume 62, Issue 6, pp. 939 - 947
Aims/hypothesis Recently, safety data signalled an increased risk of amputations in people taking canagliflozin, a sodium-glucose cotransporter 2 (SGLT2)... 
Type 2 diabetes | Diuretics | Lower limb revascularisation | Lower limb amputation | SCORE | DISEASE | ENDOCRINOLOGY & METABOLISM | ISCHEMIA | INHIBITORS | HYPERTENSION | LOWER-EXTREMITY AMPUTATIONS | Diabetes | Sodium | Diabetes mellitus (non-insulin dependent) | Diabetes mellitus | Amputation | Life Sciences
Journal Article
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue Supplement 1, p. 550
Diabetic kidney disease drives premature mortality among patients with type 1 diabetes. The role of age at diabetes onset is controversial. We analyzed risk... 
Creatinine | Kidneys | Epidermal growth factor receptors | Diabetes mellitus | Diabetes mellitus (insulin dependent) | Diabetes | Kidney diseases | Multivariate analysis | Risk factors | Age | Glomerular filtration rate
Journal Article
Obesity Surgery, ISSN 0960-8923, 5/2019, Volume 29, Issue 5, pp. 1514 - 1520
Obesity is a risk factor for chronic kidney disease (CKD) and a relative contraindication for renal transplantation. Bariatric surgery (BS) is an option to... 
Roux-en-Y gastric bypass | Medicine & Public Health | Surgery | Weight loss | Chronic kidney disease stages | Benefit/risk ratio | Sleeve gastrectomy | SURGERY | DETERMINANTS | SAFETY | TRANSPLANT | OBESITY | BODY-MASS INDEX | HEMODIALYSIS | OUTCOMES | Gastrointestinal surgery | Kidney diseases
Journal Article
Diabetes, obesity & metabolism, 05/2019
Low 1,5-anhydroglucitol (1,5-AG) is a marker of glycosuric hyperglycemia. We evaluated 1,5-AG with clinical outcomes and assessed the effects of glucose- and... 
Journal Article
by Pennells, Lisa and Kaptoge, Stephen and Wood, Angela and Sweeting, Mike and Zhao, Xiaohui and White, Ian and Burgess, Stephen and Willeit, Peter and Bolton, Thomas and Moons, Karel G M and van der Schouw, Yvonne T and Selmer, Randi and Khaw, Kay-Tee and Gudnason, Vilmundur and Assmann, Gerd and Amouyel, Philippe and Salomaa, Veikko and Kivimaki, Mika and Nordestgaard, Børge G and Blaha, Michael J and Kuller, Lewis H and Brenner, Hermann and Gillum, Richard F and Meisinger, Christa and Ford, Ian and Knuiman, Matthew W and Rosengren, Annika and Lawlor, Debbie A and Völzke, Henry and Cooper, Cyrus and Marín Ibañez, Alejandro and Casiglia, Edoardo and Kauhanen, Jussi and Cooper, Jackie A and Rodriguez, Beatriz and Sundström, Johan and Barrett-Connor, Elizabeth and Dankner, Rachel and Nietert, Paul J and Davidson, Karina W and Wallace, Robert B and Blazer, Dan G and Björkelund, Cecilia and Donfrancesco, Chiara and Krumholz, Harlan M and Nissinen, Aulikki and Davis, Barry R and Coady, Sean and Whincup, Peter H and Jørgensen, Torben and Ducimetiere, Pierre and Trevisan, Maurizio and Engström, Gunnar and Crespo, Carlos J and Meade, Tom W and Visser, Marjolein and Kromhout, Daan and Kiechl, Stefan and Daimon, Makoto and Price, Jackie F and Gómez de la Cámara, Agustin and Wouter Jukema, J and Lamarche, Benoît and Onat, Altan and Simons, Leon A and Kavousi, Maryam and Ben-Shlomo, Yoav and Gallacher, John and Dekker, Jacqueline M and Arima, Hisatomi and Shara, Nawar and Tipping, Robert W and Roussel, Ronan and Brunner, Eric J and Koenig, Wolfgang and Sakurai, Masaru and Pavlovic, Jelena and Gansevoort, Ron T and Nagel, Dorothea and Goldbourt, Uri and Barr, Elizabeth L M and Palmieri, Luigi and Njølstad, Inger and Sato, Shinichi and Monique Verschuren, W M and Varghese, Cherian V and Graham, Ian and Onuma, Oyere and Greenland, Philip and Woodward, Mark and Ezzati, Majid and Psaty, Bruce M and Sattar, Naveed and Jackson, Rod and Ridker, Paul M and Cook, Nancy R and D'Agostino, Ralph B and Thompson, Simon G and Danesh, John and Di Angelantonio, Emanuele and Emerging Risk Factors Collaboratio and Emerging Risk Factors Collaboration
European Heart Journal, ISSN 0195-668X, 02/2019, Volume 40, Issue 7, pp. 621 - 631
Abstract Aims There is debate about the optimum algorithm for cardiovascular disease (CVD) risk estimation. We conducted head-to-head comparisons of four... 
Cardiovascular disease | Risk prediction | Risk algorithms | Discrimination | Calibration | FRAMINGHAM | CARDIAC & CARDIOVASCULAR SYSTEMS | GUIDELINES | STATIN USE | VALIDATION | DISEASE PREVENTION | PREDICTION | TASK-FORCE | SCORES | PRIMARY PREVENTION | Clinical Research
Journal Article
by Pollack, Samuela and Igo, Robert P and Igo, Robert P and Jensen, Richard A and Christiansen, Mark and Christiansen, Mark and Li, Xiaohui and Li, Xiaohui and Cheng, Ching-Yu and Cheng, Ching-Yu and Ng, Maggie C Y and Ng, Maggie C.Y and Smith, Albert V and Smith, Albert V and Rossin, Elizabeth J and Segrè, Ayellet V and Davoudi, Samaneh and Tan, Gavin S and Chen, Yii-Der Ida and Kuo, Jane Z and Kuo, Jane Z and Dimitrov, Latchezar M and Stanwyck, Lynn K and Meng, Weihua and Meng, Weihua and Hosseini, S. Mohsen and Hosseini, S Mohsen and Imamura, Minako and Imamura, Minako and Nousome, Darryl and Kim, Jihye and Hai, Yang and Jia, Yucheng and Jia, Yucheng and Ahn, Jeeyun and Leong, Aaron and Shah, Kaanan and Park, Kyu Hyung and Park, Kyu Hyung and Guo, Xiuqing and Ipp, Eli and Ipp, Eli and Taylor, Kent D and Adler, Sharon G and Sedor, John R and Sedor, John R and Freedman, Barry I and Freedman, Barry I and Lee, I-Te and Sheu, Wayne H.-H and Lee, I-Te and Sheu, Wayne H-H and Kubo, Michiaki and Takahashi, Atsushi and Kubo, Michiaki and Hadjadj, Samy and Takahashi, Atsushi and Marre, Michel and Hadjadj, Samy and Tregouet, David-Alexandre and Marre, Michel and Mckean-Cowdin, Roberta and Tregouet, David-Alexandre and Mckean-Cowdin, Roberta and Varma, Rohit and Varma, Rohit and McCarthy, Mark I and Groop, Leif and McCarthy, Mark I and Groop, Leif and Ahlqvist, Emma and Ahlqvist, Emma and Lyssenko, Valeriya and Lyssenko, Valeriya and Agardh, Elisabet and Morris, Andrew and Agardh, Elisabet and Doney, Alex S.F and Morris, Andrew and Doney, Alex S F and Colhoun, Helen M and Colhoun, Helen M and Toppila, Iiro and Sandholm, Niina and Toppila, Iiro and Sandholm, Niina and Groop, Per-Henrik and Maeda, Shiro and Groop, Per-Henrik and Maeda, Shiro and Hanis, Craig L and Hanis, Craig L and Penman, Alan and Chen, Ching J and Penman, Alan and Hancock, Heather and Chen, Ching J and Hancock, Heather and Mitchell, Paul and Craig, Jamie E and ... and DCCT EDIC Res Grp and Family Invest Nephropathy Diabet-E and Family Investigation of Nephropathy and Diabetes-Eye Research Group, DCCT/EDIC Research Group
Diabetes, ISSN 0012-1797, 02/2019, Volume 68, Issue 2, pp. 441 - 456
Journal Article