X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (122) 122
Patent (32) 32
Publication (7) 7
Conference Proceeding (6) 6
Magazine Article (2) 2
Book Chapter (1) 1
Streaming Audio (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (26) 26
index medicus (23) 23
chemistry (17) 17
animals (15) 15
enzymes (14) 14
oxidation-reduction (13) 13
biochemistry & molecular biology (12) 12
chemistry, multidisciplinary (11) 11
dna adduct formation (11) 11
dna adducts - metabolism (11) 11
inorganic chemistry (11) 11
metabolic-activation (11) 11
oxidation (10) 10
rats (10) 10
sudan i (10) 10
cytochrome b (9) 9
cytochrome p450 (9) 9
metabolism (9) 9
models, molecular (9) 9
catalysis (8) 8
dna (8) 8
metallurgy (8) 8
molecular modeling (8) 8
dna adducts (7) 7
electricity (7) 7
male (7) 7
metabolites (7) 7
naphthols - metabolism (7) 7
protein binding (7) 7
toxicology (7) 7
analysis (6) 6
aristolochic acid (6) 6
balkan endemic nephropathy (6) 6
benzenediazonium ion (6) 6
blasting (6) 6
carcinogens (6) 6
catalytic domain (6) 6
chinese herbs nephropathy (6) 6
cytochrome (6) 6
cytochrome p-450 (6) 6
cytochrome p-450 cyp1a1 - metabolism (6) 6
engineering elements and units (6) 6
general measures for producing and maintaining effectivefunctioning of machines or installations (6) 6
heating (6) 6
lighting (6) 6
mechanical engineering (6) 6
nadh dehydrogenase (6) 6
organic chemistry (6) 6
p-32 postlabeling analysis (6) 6
prostaglandin-h synthase (6) 6
reductive activation (6) 6
thermal insulation in general (6) 6
urothelial cancer (6) 6
weapons (6) 6
activation (5) 5
anticancer drug ellipticine (5) 5
aristolochic acids - chemistry (5) 5
article (5) 5
aryl hydrocarbon hydroxylases - metabolism (5) 5
carcinogen (5) 5
carcinogens - metabolism (5) 5
carcinogens - toxicity (5) 5
chemistry, physical (5) 5
compounds containing metals not covered by subclassesc01d or c01f (5) 5
conversion or distribution of electric power (5) 5
cytochrome b5 (5) 5
cytochrome p-450 cyp1a2 - chemistry (5) 5
cytochromes b5 - metabolism (5) 5
cytochromes p450 (5) 5
cytochromes p450 1a1 (5) 5
ellipticine (5) 5
expression (5) 5
generation (5) 5
high pressure liquid chromatography (5) 5
installation of electric cables or lines, or of combinedoptical and electric cables or lines (5) 5
joints or fittings for pipes (5) 5
mass spectrometry (5) 5
means for thermal insulation in general (5) 5
molecular dynamics (5) 5
non-aminoazo dye (5) 5
performing operations (5) 5
peroxidase (5) 5
physics (5) 5
pipes (5) 5
proteins (5) 5
rabbits (5) 5
recombinant proteins - metabolism (5) 5
sulfotransferases - metabolism (5) 5
supports for pipes, cables or protective tubing (5) 5
thermodynamics (5) 5
transporting (5) 5
acetyltransferases - metabolism (4) 4
analytical chemistry (4) 4
aristolochic acids - metabolism (4) 4
binding sites (4) 4
biology (4) 4
chemical properties (4) 4
chemistry/food science, general (4) 4
computer simulation (4) 4
cytochrome p-450 enzyme system - metabolism (4) 4
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (156) 156
Czech (10) 10
German (3) 3
Slovak (3) 3
Russian (2) 2
Ukrainian (2) 2
Latin (1) 1
Slovenian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Chemical Research in Toxicology, ISSN 0893-228X, 04/2016, Volume 29, Issue 4, pp. 626 - 636
Eukaryotic cytochromes P450 (P450) are membrane-bound enzymes oxidizing a broad spectrum of hydrophobic substrates, including xenobiotics. Protein–protein... 
Journal Article
Chemical Society Reviews, ISSN 0306-0012, 2019
Protoporphyrin IX iron complex (heme) is an important cofactor for oxygen transfer, oxygen storage, oxygen activation, and electron transfer when bound to the... 
Journal Article
Physical Chemistry Chemical Physics, ISSN 1463-9076, 11/2016, Volume 18, Issue 44, pp. 30344 - 30356
Cytochrome P450 1A2 (P450 1A2, CYP1A2) is a membrane-bound enzyme that oxidizes a broad range of hydrophobic substrates. The structure and dynamics of both the... 
Self assembly | Enzymes | Membranes | Molecular structure | Tunnels (transportation) | Catalysts | Lipids | Catalysis
Journal Article
Chemical research in toxicology, ISSN 0893-228X, 04/2016, Volume 29, Issue 4, pp. 626 - 636
Journal Article
Biochemistry, ISSN 0006-2960, 10/2014, Volume 53, Issue 42, pp. 6695 - 6705
Formation of transient complexes of cytochrome P450 (P450) with another protein of the endoplasmic reticulum membrane, cytochrome b5 (cyt b5), dictates the... 
Cytochrome P-450 CYP1A2 - chemistry | Humans | Protein Conformation | Molecular Docking Simulation | Cytochromes b5 - chemistry | Static Electricity | Molecular Dynamics Simulation | Index Medicus
Journal Article
Journal Article
The Journal of Physical Chemistry B, ISSN 1520-6106, 06/2006, Volume 110, Issue 21, pp. 10557 - 10566
A reference system for DNA replication fidelity was studied by free energy perturbation (FEP) and linear interaction energy (LIE) methods. The studied system... 
Journal Article
Journal of Inorganic Biochemistry, ISSN 0162-0134, 12/2019, Volume 201, p. 110833
Heme-based oxygen sensors allow bacteria to regulate their activity based on local oxygen levels. YddV, a globin-coupled oxygen sensor with diguanylate cyclase... 
Globin-coupled oxygen sensor | Signal transduction | Intramolecular catalytic regulation | Diguanylate cyclase | Heme-based oxygen sensor
Journal Article
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 09/2011, Volume 82, Issue 6, pp. 669 - 680
Ellipticine is a pro-drug, whose activation is dependent on its oxidation by cytochromes P450 (CYP) and peroxidases. Cytochrome b alters the ratio of... 
Cytochrome b5 | Ellipticine | Activation | Modulation | CYP1A1/2 | Cytochrome b
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1661-6596, 07/2019, Volume 20, Issue 14, p. 3392
The metabolism of vandetanib, a tyrosine kinase inhibitor used for treatment of symptomatic/ progressive medullary thyroid cancer, was studied using human... 
1A1 | SIGNALING PATHWAYS | RAT | SUDAN-I | TYROSINE-KINASE INHIBITORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA ADDUCT FORMATION | CHEMISTRY, MULTIDISCIPLINARY | cytochromes P450 | vandetanib | ELLIPTICINE | metabolism | tyrosine kinase inhibitor | flavin-containing monoxygenases | FLAVIN-CONTAINING MONOOXYGENASE | EXPRESSION
Journal Article
Biochemistry, ISSN 0006-2960, 10/2014, Volume 53, Issue 42, pp. 6695 - 6705
Formation of transient complexes of cytochrome P450 (P450) with another protein of the endoplasmic reticulum membrane, cytochrome b 5 (cyt b 5), dictates the... 
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 10/2016, Volume 84, Issue 10, pp. 1375 - 1389
ABSTRACT The oxygen sensor histidine kinase AfGcHK from the bacterium Anaeromyxobacter sp. Fw 109‐5 forms a two‐component signal transduction system together... 
heme‐based oxygen sensor | analytical ultracentrifugation | homology modeling | two‐component signal transduction system | protein–protein interaction | hydrogen‐deuterium exchange | histidine kinase | protein–protein docking | hydrogen-deuterium exchange | two-component signal transduction system | heme-based oxygen sensor | COMPLEX | protein-protein docking | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSDUCTION | MASS-SPECTROMETRY | COUPLED HISTIDINE KINASE | PROTEIN INTERACTIONS | BIOPHYSICS | protein-protein interaction | SEDIMENTATION-VELOCITY | EXCHANGE | BINDING | AUTOPHOSPHORYLATION | Histidine Kinase - chemistry | Histidine Kinase - metabolism | Phosphorylation | Heme - metabolism | Bacterial Proteins - chemistry | Histidine - metabolism | Oxygen - metabolism | Deuterium Exchange Measurement | Heme - chemistry | Cloning, Molecular | Escherichia coli - metabolism | Oxygen - chemistry | Protein Domains | Aeromonas salmonicida - metabolism | Recombinant Proteins - metabolism | Protein Structure, Secondary | Signal Transduction | Iron - chemistry | Bacterial Proteins - genetics | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Iron - metabolism | Myxococcales - chemistry | Escherichia coli - genetics | Histidine Kinase - genetics | Myxococcales - enzymology | Aspartic Acid - metabolism | Bacterial Proteins - metabolism | Structural Homology, Protein | Aspartic Acid - chemistry | Histidine - chemistry | Aeromonas salmonicida - genetics | Proteins | Phosphates | Hydrogen | Analysis | Heme | Cellular signal transduction | Mass spectrometry | Protein-protein interactions
Journal Article
Monatshefte für Chemie - Chemical Monthly, ISSN 0026-9247, 11/2017, Volume 148, Issue 11, pp. 1983 - 1991
Ellipticine is an anticancer agent that forms covalent DNA adducts after enzymatic activation by cytochrome P450 (CYP) enzymes, mainly by CYP3A4. This process... 
Theoretical and Computational Chemistry | Enzymes | Chemistry | Analytical Chemistry | Coenzymes | Chemistry/Food Science, general | Physical Chemistry | DNA | High pressure liquid chromatography | Inorganic Chemistry | Organic Chemistry
Journal Article