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Cancer Cell, ISSN 1535-6108, 12/2012, Volume 22, Issue 6, pp. 812 - 824
Journal Article
Nature Communications, ISSN 2041-1723, 05/2017, Volume 8, Issue 1, p. 15424
The indisputable role of epigenetics in cancer and the fact that epigenetic alterations can be reversed have favoured development of epigenetic drugs. In this... 
LYSINE METHYLTRANSFERASE G9A | CELLS | MAINTENANCE | DNA METHYLATION | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | TRANSCRIPTION | H3K9 | DI-METHYLATION | HISTONE METHYLTRANSFERASE | CHEMOTHERAPY | Histocompatibility Antigens - genetics | Apoptosis - drug effects | DNA Modification Methylases - antagonists & inhibitors | Hematologic Neoplasms - mortality | Humans | Histocompatibility Antigens - chemistry | Apoptosis - genetics | Crystallography, X-Ray | Antineoplastic Agents - therapeutic use | Interferons - immunology | Dose-Response Relationship, Drug | Histone-Lysine N-Methyltransferase - antagonists & inhibitors | Enzyme Inhibitors - chemistry | Drug Design | Female | Antineoplastic Agents - pharmacology | Epigenesis, Genetic - drug effects | Drug Evaluation, Preclinical | Histocompatibility Antigens - metabolism | Cell Proliferation - genetics | Histone-Lysine N-Methyltransferase - genetics | DNA Modification Methylases - metabolism | Enzyme Inhibitors - pharmacology | Treatment Outcome | Antineoplastic Agents - chemistry | Enzyme Inhibitors - therapeutic use | DNA Modification Methylases - chemistry | Histone-Lysine N-Methyltransferase - chemistry | Xenograft Model Antitumor Assays | DNA Modification Methylases - genetics | Animals | Apoptosis - immunology | Histone-Lysine N-Methyltransferase - metabolism | Survival Analysis | Cell Line, Tumor | Hematologic Neoplasms - drug therapy | Interferons - metabolism | Cell Proliferation - drug effects | Hematologic Neoplasms - genetics | Mice | Mice, Inbred BALB C | Molecular Docking Simulation | Hematologic Neoplasms - immunology | Microsomes, Liver
Journal Article
Blood, ISSN 0006-4971, 11/2009, Volume 114, Issue 22, pp. 3943 - 3943
Abstract Abstract 3943 Poster Board III-879 The nuclear factor κB (NF-κB) family of transcription factors is required for the development of T and B... 
Journal Article
Blood, ISSN 0006-4971, 05/2019, Volume 133, Issue 22, pp. 2401 - 2412
Refractory or relapsed diffuse large B-cell lymphoma (DLBCL) often associates with the activated B-cell-like (ABC) subtype and genetic alterations that drive... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 5115 - 5115
Abstract The epigenomic changes that occur during the process of cellular differentiation, such as in the blood cell lineage, are currently not well... 
Journal Article
Nature Communications, ISSN 2041-1723, 06/2014, Volume 5, Issue 1, p. 3904
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 1527 - 1527
Background: Although MYD88 L265P is highly frequent in WM, by itself is insufficient to explain disease progression since most cases with IgM MGUS also have... 
Journal Article
British Journal of Haematology, ISSN 0007-1048, 09/2012, Volume 158, Issue 6, pp. 712 - 726
Summary Using high‐resolution genomic microarray analysis, a distinct genomic profile was defined in 114 samples from patients with splenic marginal zone... 
B cell lymphoma | IRF5 | chromosome deletion | Chromosome deletion | REGULATORY FACTOR 5 | TRANSFORMATION | TRANSLOCATIONS | VILLOUS LYMPHOCYTES | UNIPARENTAL DISOMY | HYBRIDIZATION | IDENTIFICATION | B-CELL LYMPHOMA | GENE-EXPRESSION | MUTATIONS | HEMATOLOGY | Chromosomes, Human, Pair 7 - ultrastructure | Sequence Deletion | Translocation, Genetic | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Apoptosis - genetics | Cell Line, Tumor - transplantation | Interferon Regulatory Factors - deficiency | Lymphoma, B-Cell, Marginal Zone - mortality | Splenic Neoplasms - mortality | Interferon Regulatory Factors - biosynthesis | Interferon Regulatory Factors - physiology | Lymphoma, B-Cell, Marginal Zone - pathology | Neoplasm Proteins - genetics | Genes, Tumor Suppressor | Real-Time Polymerase Chain Reaction | Genetic Association Studies | Neoplasm Proteins - biosynthesis | Oligonucleotide Array Sequence Analysis - methods | Splenic Neoplasms - genetics | Kaplan-Meier Estimate | Interferon Regulatory Factors - genetics | Cell Division - drug effects | Lymphoma, B-Cell, Marginal Zone - genetics | Mice, Knockout | Genes, Immunoglobulin | Point Mutation | Animals | Splenic Neoplasms - pathology | Comparative Genomic Hybridization | High-Throughput Nucleotide Sequencing | Mice | Chromosomes, Human, Pair 7 - genetics | Cell proliferation | Spleen | Nucleotide sequence | Insertion | Nucleotides | Gene deletion | chromosome 7 | Point mutation | genomics | Gene mapping | Apoptosis | B-cell lymphoma | uniparental disomy
Journal Article
Blood, ISSN 0006-4971, 06/2003, Volume 101, Issue 11, pp. 4539 - 4546
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2018, Volume 61, Issue 15, pp. 6546 - 6573
Epigenetic regulators that exhibit aberrant enzymatic activities or expression profiles are potential therapeutic targets for cancers. Specifically, enzymes... 
DESIGN | METHYLATION | CHEMISTRY, MEDICINAL | INHIBITORS | PATENT
Journal Article
Cancer Research, ISSN 0008-5472, 04/2005, Volume 65, Issue 8, pp. 3264 - 3272
Journal Article
by Sole and Espinet and Sanz and Cervera and Calasanz and Luno and Prieto and Granada and Hernandez and Cigudosa and Diez and Bureo and Marques and Arranz and Rios and Martinez Climent and Vallespi and Florensa and Woessner
British Journal of Haematology, ISSN 0007-1048, 02/2000, Volume 108, Issue 2, pp. 346 - 356
Recently, a consensus International Prognostic Scoring System (IPSS) for predicting outcome and planning therapy in the myelodysplastic syndromes (MDS) has... 
karyotype | cytogenetics | prognosis | myelodysplastic syndromes | chromosomes | Cytogenetics | Prognosis | Chromosomes | Karyotype | Myelodysplastic syndromes | SURVIVAL | PRELEUKEMIA | INTERNATIONAL SCORING SYSTEM | LEUKEMIA | HEMATOLOGY | MORPHOLOGY | CYTOGENETIC ANALYSIS
Journal Article