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Nature Medicine, ISSN 1078-8956, 02/2013, Volume 19, Issue 2, pp. 193 - 201
Journal Article
Breast Cancer Research, ISSN 1465-5411, 07/2013, Volume 15, Issue 4, pp. R54 - R54
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e55203 - e55203
Aeroplysinin-1 is a brominated antibiotic used by some sponges for defense against bacterial pathogen invasion. Aeroplysinin-1 has a wide spectrum of... 
APLYSINA-AEROPHOBA | CHEMICAL DEFENSE | IN-VITRO | SPONGE VERONGIA-AEROPHOBA | VIVO | MMP-1 | MEMBRANE | MULTIDISCIPLINARY SCIENCES | DISEASE | RECEPTOR | ANGIOGENESIS ASSAYS | Human Umbilical Vein Endothelial Cells | Cyclooxygenase 2 Inhibitors - pharmacology | Endothelial Cells - metabolism | Humans | Angiogenesis Inhibitors - pharmacology | Monocytes - metabolism | Cyclohexenes - analysis | Gene Expression Regulation - drug effects | Tetrazolium Salts | Acetonitriles - analysis | Animals | Thiazoles | Cyclohexenes - pharmacology | Inhibitory Concentration 50 | Acetonitriles - pharmacology | Cell Proliferation - drug effects | Chemokine CCL2 - metabolism | Thrombospondin 1 - metabolism | Porifera - chemistry | Genetic research | COX-2 inhibitors | DNA microarrays | Genes | Endothelium | Bromination | Genomics | Interleukin | Cardiovascular disease | Biochemistry | Matrix metalloproteinase | Kinases | Western blotting | Prostaglandin endoperoxide synthase | Proteins | Angiogenesis | Epidermal growth factor | Rodents | Aorta | Bacteria | Tumor necrosis factor-TNF | Metalloproteinase | Interstitial collagenase | Thrombospondin | Cytokines | Pharmacology | Inflammation | Gene expression | Endothelial cells | Chronic fatigue syndrome | Antibiotics | Monocyte chemoattractant protein | TNF inhibitors | Cyclooxygenase-2 | Molecular biology | Monocyte chemoattractant protein 1 | Index Medicus
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 10/2019, Volume 168, pp. 366 - 383
Phytohormones have shown great potential as natural anticancer compounds, being interesting in cancer prevention and therapy. Strigolactones are a class of... 
VEGFR2 | Angiogenesis | FAK | Cytoskeleton | GR-24 | Prevention | Plant hormones | Analysis | Endothelium | Cancer | Index Medicus
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 385, pp. 1 - 11
Abstract The natural bioactive compound damnacanthal inhibits several tyrosine kinases. Herein, we show that -in fact-damancanthal is a multi kinase inhibitor.... 
Hematology, Oncology and Palliative Medicine | Angiogenesis | Noni | Multi-kinase inhibitor | Damnacanthal | Morinda citrifolia | VIVO | COMPOUND | PROTEIN-KINASES | IN-VITRO | ONCOLOGY | ENDOTHELIAL-CELLS | GROWTH-FACTOR | BASEMENT-MEMBRANE | Proto-Oncogene Proteins c-met - metabolism | Neovascularization, Physiologic - drug effects | Humans | Extracellular Matrix - metabolism | Structure-Activity Relationship | Zebrafish - embryology | Dose-Response Relationship, Drug | Protein Kinase Inhibitors - chemistry | Receptor, Epidermal Growth Factor - metabolism | Cattle | Focal Adhesion Kinase 1 - metabolism | Chorioallantoic Membrane - blood supply | Cell Line | Cell Survival - drug effects | Human Umbilical Vein Endothelial Cells - drug effects | Proto-Oncogene Proteins c-met - antagonists & inhibitors | Extracellular Matrix - drug effects | Angiogenesis Inhibitors - pharmacology | Cell Adhesion - drug effects | Chick Embryo | Molecular Dynamics Simulation | Receptor, Epidermal Growth Factor - chemistry | Cell Movement - drug effects | Animals | Human Umbilical Vein Endothelial Cells - enzymology | Signal Transduction - drug effects | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Protein Conformation | Anthraquinones - pharmacology | Cell Proliferation - drug effects | Molecular Docking Simulation | Protein Kinase Inhibitors - pharmacology | Proto-Oncogene Proteins c-met - chemistry | Anthraquinones - chemistry | Focal Adhesion Kinase 1 - antagonists & inhibitors | Focal Adhesion Kinase 1 - chemistry | Angiogenesis Inhibitors - chemistry | Antimitotic agents | Tyrosine | Endothelial growth factors | Molecular dynamics | Antineoplastic agents | Phosphotransferases | Endothelium | Extracellular matrix | Experiments | Rodents | Cancer | Index Medicus
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 05/2018, Volume 83, Issue 10, pp. 5365 - 5383
New synthetic strategies directed toward the novel cyclopeptides solomonamides have been explored utilizing an olefin metathesis as the key reaction. In the... 
ENYNE METATHESIS | ALPHA,BETA-UNSATURATED GAMMA,DELTA-EPOXY ESTERS | ANALOGS | OLEFIN CROSS-METATHESIS | BUILDING-BLOCKS | ISOMERIZATION | BIOLOGICAL EVALUATION | CHEMISTRY, ORGANIC | ALLYLIC HYDROXY GROUP | TERMINAL ALKYNES | DOUBLE INVERSION | Index Medicus
Journal Article
Oncotarget, ISSN 1949-2553, 04/2018, Volume 9, Issue 25, pp. 17349 - 17367
Biocomputational network approaches are being successfully applied to predict and extract previously unknown information of novel molecular components of... 
Angiogenesis | Wound scratch assay | Matrigel assay | Predictive networks | Superoxide dismutase 3
Journal Article
Journal Article
Circulation Research, ISSN 0009-7330, 05/2016, Volume 118, Issue 10, pp. 1480 - 1497
Journal Article
Cardiovascular Research, ISSN 0008-6363, 11/2016, Volume 112, Issue 2, pp. 568 - 580
To determine the role of NOTCH during the arterial injury response and the subsequent chronic arterial-wall inflammation underlying atherosclerosis. We have... 
Inflammation | Transcriptional regulation | NF-jB | Atherosclerosis | Notch | Endothelium | CARDIAC & CARDIOVASCULAR SYSTEMS | T-CELL LEUKEMIA | PHENOTYPE | MACROPHAGE ACTIVATION | VASCULAR INJURY | CROSS-TALK | NF-kappa B | PATHWAY | MICE | NF-KAPPA-B | EXPRESSION
Journal Article
Cardiovascular research, ISSN 0008-6363, 08/2016, Volume 112, Issue November 2016, p. 568
To determine the role of NOTCH during the arterial injury response and the subsequent chronic arterial-wall inflammation underlying atherosclerosis. We have... 
atherosclerosis | endothelium | NF-κB | notch | inflammation | transcriptional regulation
Journal Article
Biomolecules, ISSN 2218-273X, 08/2019, Volume 9, Issue 8, p. 332
Endothelial cells form the inner lining of blood vessels, in a process known as angiogenesis. Excessive angiogenesis is a hallmark of several diseases,... 
Index Medicus | endothelial cells | metabolism | lactate | glycolysis | MCT1
Journal Article
MARINE DRUGS, ISSN 1660-3397, 04/2019, Volume 17, Issue 4, p. 228
Marine sponges are a prolific source of bioactive compounds. In this work, the putative antiangiogenic potential of a series of synthetic precursors of... 
endothelial cells | CHEMISTRY, MEDICINAL | angiogenesis | TYROSINE KINASE | COMPOUND | marine sponge | Solomonamide A | METALLOPROTEINASES | PEPTIDES | DRUGS | cancer | GROWTH-FACTOR | MARINE | METABOLITE | STEPS
Journal Article