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PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, p. e0181760
Circulating levels of IGF-1 may decrease under several circumstances like ageing, metabolic syndrome, and advanced cirrhosis. This reduction is associated with... 
G(BETA-GAMMA) SUBUNITS | MYOCARDIAL-INFARCTION | HSP47 | MULTIDISCIPLINARY SCIENCES | CARDIOVASCULAR-DISEASE | RECEPTOR | MICE | ISCHEMIA-REPERFUSION | INSULIN SENSITIVITY | GROWTH-FACTOR-I | DIASTOLIC DYSFUNCTION | Angiotensin II - pharmacology | Extracellular Matrix - drug effects | Body Weight - drug effects | Extracellular Matrix - metabolism | Insulin-Like Growth Factor I - deficiency | Myocardial Contraction - drug effects | Mice, Transgenic | Myocardium - pathology | Vasoconstriction - drug effects | Gene Expression Regulation - drug effects | Myocardial Contraction - genetics | Organ Size - drug effects | Animals | Perfusion | Myocardium - metabolism | Hemodynamics - drug effects | Vasodilation - drug effects | Real-Time Polymerase Chain Reaction | Bradykinin - pharmacology | Insulin-Like Growth Factor I - metabolism | Type 2 diabetes | Dyslipidemias | Angiotensin | Insulin resistance | Development and progression | Research | Gene expression | Cardiovascular diseases | Risk factors | Heart | Calcium | Peptides | Insulin-like growth factor I | Dyslipidemia | Insulin-like growth factors | Kinases | Proteins | Calcium signalling | Reduction | Reperfusion | Ischemia | Vasoactive agents | Rodents | Extracellular matrix | Angiotensin II | Heart diseases | Diabetes mellitus | Health risks | Contractility | Coronary circulation | Histology | Insulin | Muscle contraction | Coronary artery disease | Cirrhosis | DNA microarrays | Fibrosis | Metabolic disorders | Circulation | Calcium (extracellular) | Structure-function relationships
Journal Article
Journal of clinical medicine research, ISSN 1918-3003, 04/2017, Volume 9, Issue 4, pp. 233 - 247
Cirrhosis represents the final stage of chronic liver damage, which can be due to different factors such as alcohol, metabolic syndrome with liver steatosis,... 
IGF-1 axis | Mitochondrial protection | Oxidative damage | IGF-1 | Review | Non-alcoholic fatty liver disease | Acute liver damage | Fibrogenesis | Steatosis
Journal Article
Journal of Translational Medicine, ISSN 1479-5876, 10/2015, Volume 13, Issue 1, p. 326
Journal Article
Journal of Physiology and Biochemistry, ISSN 1138-7548, 05/2017, Volume 73, Issue 2, pp. 245 - 258
Even though the liver synthesizes most of circulating IGF-1, it lacks its receptor under physiological conditions. However, according to previous studies, a... 
Cytoskeleton | Extracellular matrix | IGF-1 | Hepatocytes | Tight junctions | Gene expression | PHYSIOLOGY | ATROPHY | BIOCHEMISTRY & MOLECULAR BIOLOGY | SOMATOMEDIN-C | FACTOR-BINDING-PROTEINS | TRANSPORT | CIRRHOTIC RATS | METABOLISM | OSTEOPENIA | MITOCHONDRIAL PROTECTION | HEPATOMA | GROWTH-FACTOR-I | Liver - pathology | Tight Junction Proteins - genetics | Cadherins - metabolism | Oxidative Stress | Cytoskeletal Proteins - genetics | Male | Gene Expression Profiling | Insulin-Like Growth Factor I - genetics | Acute-Phase Proteins - genetics | Desmosomes - pathology | Hepatitis - prevention & control | Liver - immunology | Injections, Subcutaneous | Desmosomes - immunology | Hepatitis - metabolism | Inflammation Mediators - metabolism | Insulin-Like Growth Factor I - administration & dosage | Cytoskeletal Proteins - metabolism | Cadherins - genetics | Insulin-Like Growth Factor I - therapeutic use | Extracellular Matrix Proteins - metabolism | Tight Junction Proteins - metabolism | Desmosomes - metabolism | Acute-Phase Proteins - metabolism | Extracellular Matrix Proteins - genetics | Liver - metabolism | Gene Expression Regulation | Hepatitis - pathology | Mice, Transgenic | Animals | Receptors, Somatomedin - metabolism | Hepatitis - immunology | Receptors, Somatomedin - genetics | Mice | Lipid Peroxidation | Insulin-Like Growth Factor I - metabolism | Crosses, Genetic | Original
Journal Article
American Journal of Medical Genetics Part A, ISSN 1552-4825, 02/2017, Volume 173, Issue 2, pp. 537 - 540
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 07/2016, Volume 1862, Issue 7, pp. 1267 - 1278
Journal Article
Clinical Case Reports, ISSN 2050-0904, 02/2018, Volume 6, Issue 2, pp. 426 - 431
Key Clinical Message We report a case of short stature irresponsive to growth hormone (GH) replacement therapy. Low GH response to provocative tests and... 
IGF‐1 | GH insensitivity | GH resistance | Laron Syndrome | GH/IGF‐1 axis | IGF-1 | GH/IGF-1 axis
Journal Article
Clinical Case Reports, ISSN 2050-0904, 11/2017, Volume 5, Issue 11, pp. 1852 - 1855
Key Clinical Message Glucose and lipid profile together with blood pressure should always be considered for low sera‐IGF‐1 patients. Even when adulthood is... 
GHR | IGF‐1 | metabolic syndrome | GH insensitivity | type 2 diabetes | GH/IGF‐1 axis | Laron syndrome | stroke | obesity | IGF-1 | GH/IGF-1 axis | Metabolism | Diabetes
Journal Article
Endocrinology, diabetes & metabolism case reports, ISSN 2052-0573, 2017, Volume 2017, Issue 1, pp. 1 - 5
Herein, we present a 14-year-old patient with short stature (134 cm) referred from Paediatrics to our department for complementary evaluation since growth... 
Journal Article
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