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Science, ISSN 0036-8075, 05/2015, Volume 348, Issue 6237, pp. 880 - 886
How somatic mutations accumulate in normal cells is central to understanding cancer development but is poorly understood. We performed ultradeep sequencing of... 
EVOLUTION | LANDSCAPE | CLONAL HEMATOPOIESIS | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | SQUAMOUS-CELL CARCINOMA | CANCER GENOME | LEUKEMIA | NONMELANOMA | ACTIVATING MUTATIONS | Antibody diversity | Research | Natural selection | Mutation | Skin cancer | Mutations | Landscapes | Genes | Epidermis | Evolution | Survival | Tumors | Cancer
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2016, Volume 113, Issue 9, pp. E1128 - E1129
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 06/2018, Volume 115, Issue 26, pp. E6010 - E6019
Journal Article
by Tarabichi, Maxime and Tarabichi, Maxime and Martincorena, Iñigo and Gerstung, Moritz and Gerstung, Moritz and Leroi, Armand M and Markowetz, Florian and Markowetz, Florian and Dentro, Stefan C and Leshchiner, Ignaty and Spellman, Paul T and Morris, Quaid D and Jolly, Clemency and Lingjærde, Ole Christian and Haase, Kerstin and Wedge, David C and Wintersinger, Jeff and Deshwar, Amit G and Van Loo, Peter and Yu, Kaixian and Gonzalez, Santiago and Rubanova, Yulia and Macintyre, Geoff and Adams, David J and Anur, Pavana and Beroukhim, Rameen and Boutros, Paul C and Bowtell, David D and Campbell, Peter J and Cao, Shaolong and Christie, Elizabeth L and Cmero, Marek and Cun, Yupeng and Dawson, Kevin J and Demeulemeester, Jonas and Donmez, Nilgun and Drews, Ruben M and Eils, Roland and Fan, Yu and Fittall, Matthew and Garsed, Dale W and Getz, Gad and Ha, Gavin and Imielinski, Marcin and Jerman, Lara and Ji, Yuan and Kleinheinz, Kortine and Lee, Juhee and Lee-Six, Henry and Livitz, Dimitri G and Malikic, Salem and Mitchell, Thomas J and Mustonen, Ville and Oesper, Layla and Peifer, Martin and Peto, Myron and Raphael, Benjamin J and Rosebrock, Daniel and Sahinalp, S. Cenk and Salcedo, Adriana and Schlesner, Matthias and Schumacher, Steven and Sengupta, Subhajit and Shi, Ruian and Shin, Seung Jun and Stein, Lincoln D and Vázquez-García, Ignacio and Vembu, Shankar and Wheeler, David A and Yang, Tsun-Po and Yao, Xiaotong and Yuan, Ke and Zhu, Hongtu and Wang, Wenyi and Morris, Quaid D and Spellman, Paul T and Wedge, David C and Van Loo, Peter and Lingjærde, Ole Christian and PCAWG Evolution Heterogeneity and PCAWG Evolution and Heterogeneity Working Group and The PCAWG Evolution and Heterogeneity Working Group
Nature Genetics, ISSN 1061-4036, 12/2018, Volume 50, Issue 12, pp. 1630 - 1633
According to this traditional model, the selective advantage is conferred by a small set of driver mutations, but as the subclones that bear them successively... 
PATTERNS | CLONAL EVOLUTION | CANCER | GENETICS & HEREDITY | Research | Neutral evolution | Oncology, Experimental | Cancer | Genetic drift | Medical research | Computer simulation | Neutrality | Genomes | Gene sequencing | Genetic variance | Simulation | Cell death | Frequency distribution | Drift | Mutation | Charitable foundations | Tumors | Apoptosis
Journal Article
Journal Article
Nature, ISSN 0028-0836, 09/2014, Volume 513, Issue 7518, pp. 422 - 5
Journal Article
ISSN 0036-8075, 2018
The extent to which cells in normal tissues accumulate mutations throughout life is poorly understood. Some mutant cells expand into clones that can be... 
Journal Article