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Journal of Neuroscience Research, ISSN 0360-4012, 06/2016, Volume 94, Issue 6, pp. 568 - 578
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 11/2017, Volume 16, Issue 11, pp. 2351 - 2363
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 06/2016, Volume 94, Issue 6, p. 568
  Alterations in the ratio of excitatory to inhibitory transmission are emerging as a common component of many nervous system disorders, including autism... 
GABA | Autism | Nervous system diseases | Fragile X syndrome | Analysis | Neurophysiology | Rodents
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 06/2016, Volume 94, Issue 6, pp. 568 - 578
Alterations in the ratio of excitatory to inhibitory transmission are emerging as a common component of many nervous system disorders, including autism... 
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 08/2019, Volume 62, Issue 16, pp. 7526 - 7542
Neuroactive steroids (NASs) play a pivotal role in maintaining homeostasis is the CNS. We have discovered that one NAS in particular, 24(S)-hydroxycholesterol... 
MODES | CHEMISTRY, MEDICINAL | MECHANISMS | NMDA RECEPTORS
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2014, Volume 57, Issue 11, pp. 4584 - 4597
Journal Article
Epilepsy Research, ISSN 0920-1211, 2017, Volume 134, pp. 16 - 25
Highlights • SGE-516 is a neuroactive steroid GABAA receptor positive allosteric modulator. • SGE-516 augments α1β2γ2 and α4β3δ subunit-containing GABAA... 
Neurology | Pentylenetetrazol (PTZ) | Neuroactive steroids | Seizure | Convulsion | GABAA receptor | Allopregnanolone | MODULATORS | NEUROSTEROIDS | STATUS EPILEPTICUS | TRAFFICKING | CLINICAL NEUROLOGY | SEIZURES | INHIBITION | ELECTRICAL-STIMULATION | MOUSE MODEL | FRAGILE-X-SYNDROME | GABA(A) RECEPTORS | GABA | Anticonvulsants | Analysis | Epilepsy | Steroids | Chemotherapy | Seizures (Medicine) | Cancer
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2015, Volume 58, Issue 18, pp. 7195 - 7216
Journal Article
Annual Reports in Medicinal Chemistry, ISSN 0065-7743, 2014, Volume 49, pp. 27 - 42
Neuroactive steroids (NASs) are a family of steroid-based compounds of both natural and synthetic origin, which have been shown to impact central nervous... 
Allosteric | NAS | Endogenous | GABA | NMDA | Neuroactive steroid | Anesthetics
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2012, Volume 55, Issue 22, pp. 10010 - 10021
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 11/2015, Volume 25, Issue 22, pp. 5172 - 5177
Journal Article
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