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Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1 - 10
Niemann Pick type C (NPC) disease is a rare neurovisceral disorder. Mutations in npc1 gene induce an intracellular accumulation of unesterified cholesterol in... 
Niemann-Pick disease | Adenosine | Phenotypes | Myelin | Lysosomes | siRNA | Autophagy | Glial stem cells | Cholesterol | Mitochondria | Cell death | Oligodendrocytes | Cell lines | Fibroblasts | Neural stem cells | Npc1 protein | Adenosine A2A receptors | Membrane potential | Phagocytosis | Endosomes
Journal Article
Brain Research, ISSN 0006-8993, 2012, Volume 1476, pp. 108 - 118
Abstract The striatum is a subcortical area involved in sensorimotor, cognitive and emotional processes. Adenosine A2A receptors (A2A Rs) are highly expressed... 
Neurology | A2A adenosine receptor | CB1 cannabinoid receptor | Striatum | Glutamate release | Heteromer | adenosine receptor | cannabinoid receptor
Journal Article
Journal Article
Pharmacological Research, ISSN 1043-6618, 09/2019, Volume 147, p. 104338
Adenosine A receptor (A R) is a G-protein coupled receptor that regulates several important functions in the central nervous system. Large amount of... 
Mood disorder | Neurodevelopment | Schizophrenia | Neurodegenerative disease | Adenosine A2A receptor | Niemann-pick disease
Journal Article
Journal of Pediatrics, The, ISSN 0022-3476, 2014, Volume 164, Issue 6, pp. 1475 - 1480.e2
Journal Article
Brain Research, ISSN 0006-8993, 10/2012, Volume 1476, p. 108
The striatum is a subcortical area involved in sensorimotor, cognitive and emotional processes. Adenosine A.sub.2A receptors (A.sub.2ARs) are highly expressed... 
Adenosine | Physiological aspects | Glutamate
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 02/2018, Volume 110, pp. 1 - 11
Niemann-Pick C is a fatal neurovisceral disorder caused, in 95% of cases, by mutation of gene. Therapeutic options are extremely limited and new “druggable”... 
T1–11 | Adenosine A2A receptor | Niemann-Pick C | Cholesterol | receptor | Adenosine A
Journal Article
Aging Cell, ISSN 1474-9718, 02/2013, Volume 12, Issue 1, pp. 11 - 23
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 2019, Volume 149, Issue 2, pp. 211 - 230
Cerebral ischemia is the second most common cause of death and a major cause of disability worldwide. Available therapies are based only on anticoagulants or... 
neuroblastoma cells | receptor | adenosine A | hippocampus | cerebral ischemia | partial agonists
Journal Article