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1. Full Text Molecular Basis for High Virulence of Hong Kong H5N1 Influenza A Viruses
by Masato Hatta and Peng Gao and Peter Halfmann and Yoshihiro Kawaoka
Science (American Association for the Advancement of Science), ISSN 0036-8075, 9/2001, Volume 293, Issue 5536, pp. 1840 - 1842
Transcriptional regulatory elements | Pandemics | Influenza A virus | Virulence | Viruses | Amino acids | Reports | Infections | Kidney cells | H5N1 subtype influenza A virus | Genetic mutation | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains | Biological and medical sciences | Microbiology | Virology | Reassortant Viruses - pathogenicity | Humans | Influenza A virus - genetics | Reassortant Viruses - genetics | Reassortant Viruses - physiology | Influenza A Virus, H5N1 Subtype | Viral Proteins - metabolism | Mutation, Missense - genetics | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Lung - virology | Influenza A virus - pathogenicity | Influenza, Human - mortality | Influenza, Human - virology | RNA Replicase | Amino Acid Sequence | DNA, Recombinant - genetics | Hemagglutinin Glycoproteins, Influenza Virus - chemistry | Influenza A virus - physiology | Viral Proteins - chemistry | Birds - virology | Viral Proteins - genetics | Influenza, Human - epidemiology | Influenza, Human - transmission | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Animals | Hong Kong - epidemiology | Mice | Influenza viruses | Analysis | Communicable diseases | Proteins | Genetics | Rodents | Influenza | Index Medicus
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2. Full Text Subclinical Brain Injury Caused by H5N1 Influenza Virus Infection
by Kyoko Shinya and Akiko Makino and Masato Hatta and Shinji Watanabe and Jin Hyun Kim and Yasuko Hatta and Peng Gao and Makoto Ozawa and Quynh Mai Le and Yoshihiro Kawaoka
Journal of Virology, ISSN 0022-538X, 05/2011, Volume 85, Issue 10, pp. 5202 - 5207
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | Animals | Encephalitis, Viral - virology | Orthomyxoviridae Infections - complications | Orthomyxoviridae Infections - pathology | Olfactory Pathways - virology | Influenza A Virus, H5N1 Subtype - pathogenicity | Encephalitis, Viral - pathology | Ferrets | Orthomyxoviridae Infections - virology | Disease Models, Animal | Index Medicus | Pathogenesis and Immunity
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3. Full Text In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses
by Shinya, Kyoko and Suresh, M and Fujii, Ken and Mitamura, Keiko and Makino, Akiko and Imai, Hirotaka and Ozawa, Makoto and Kawaoka, Yoshihiro and Saito, Reiko and Sakoda, Yoshihiro and Murakami, Shin and Itoh, Yasushi and Sakai-Tagawa, Yuko and Yamazaki, Masahiko and Tamura, Daisuke and Muramoto, Yukiko and Okamatsu, Masatoshi and Nakamura, Morio and Kida, Hiroshi and Neumann, Gabriele and Noda, Takeshi and Ishigaki, Hirohito and Imai, Masaki and Ito, Mutsumi and Shult, Peter A and Furuta, Yousuke and Gern, James and Shimojima, Masayuki and Sakabe, Saori and Horimoto, Taisuke and Kakugawa, Satoshi and Takahashi, Kazuo and Hatta, Yasuko and Warshauer, David and Li, Chengjun and Watanabe, Tokiko and Takahashi, Kei and Suzuki, Hiroshi and Ogasawara, Kazumasa and Sugaya, Norio and Watanabe, Shinji and Goto, Hideo and Brockman-Schneider, Rebecca and Yamada, Shinya and Hatta, Masato and Kiso, Maki and Mitamura, Hiroshi and Iwatsuki-Horimoto, Kiyoko and Nakano, Kunio and Takano, Ryo and Nakayama, Misako and Yamashita, Makoto
Nature (London), ISSN 0028-0836, 08/2009, Volume 460, Issue 7258, pp. 1021 - 1025
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains | Antiviral agents | Microbiology | Pharmacology. Drug treatments | Biological and medical sciences | Medical sciences | Virology | Antibiotics. Antiinfectious agents. Antiparasitic agents | Macaca fascicularis - immunology | Swine Diseases - virology | Humans | Influenza A Virus, H1N1 Subtype - physiology | Male | Neutralization Tests | Ferrets - virology | Swine, Miniature - virology | Lung - virology | Primate Diseases - pathology | Female | Cell Line | Antiviral Agents - pharmacology | Lung - pathology | Swine Diseases - pathology | Influenza A Virus, H1N1 Subtype - pathogenicity | HN Protein - metabolism | Influenza A Virus, H1N1 Subtype - drug effects | Primate Diseases - virology | Animals | Orthomyxoviridae Infections - transmission | Virus Replication | Influenza A Virus, H1N1 Subtype - enzymology | Dogs | Antibodies, Viral - immunology | Mice | Mice, Inbred BALB C | Orthomyxoviridae Infections - virology | Swine - virology | Lung - immunology | Macaca fascicularis - virology | Orthomyxoviridae Infections - immunology | Influenza viruses | Genetic aspects | Properties | Swine influenza | Scanning electron microscopy | Cytokines | Swine flu | Influenza | Viruses | Avian flu | Index Medicus
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4. Full Text Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus
by Fernando, Lisa and Hyun Kim, Jin and Hatta, Masato and Feldmann, Friederike and Shinya, Kyoko and Kash, John C and Katze, Michael G and Kobasa, Darwyn and Kawaoka, Yoshihiro and Hatta, Yasuko and Alimonti, Judie B and Halfmann, Peter and Feldmann, Heinz and Copps, John and Jones, Steven M and Li, Yan and Ebihara, Hideki
Nature (London), ISSN 0028-0836, 01/2007, Volume 445, Issue 7125, pp. 319 - 323
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains | Viral diseases of the respiratory system and ent viral diseases | Infectious diseases | Microbiology | Viral diseases | Biological and medical sciences | Medical sciences | Human viral diseases | Virology | Influenza A Virus, H1N1 Subtype - immunology | Macaca fascicularis - immunology | Chemokines - blood | Oligonucleotide Array Sequence Analysis | Humans | Gene Expression Profiling | Lung - virology | Time Factors | Female | Influenza, Human - virology | Lung - metabolism | Influenza A Virus, H1N1 Subtype - genetics | Cytokines - blood | Disease Models, Animal | Lung - pathology | Gene Expression Regulation | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza, Human - blood | Survival Rate | Immunity, Innate - immunology | Animals | Virus Replication | Mice | Mice, Inbred BALB C | Macaca fascicularis - virology | Influenza, Human - immunology | Primates | Genotype & phenotype | Infections | Immunology | Influenza | Index Medicus
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5. Full Text Single-replication BM2SR vaccine provides sterilizing immunity and cross-lineage influenza B virus protection in mice
by Moser, Michael J and Hatta, Yasuko and Gabaglia, Claudia and Sanchez, Adriana and Dias, Peter and Sarawar, Sally and Kawaoka, Yoshihiro and Hatta, Masato and Neumann, Gabriele and Bilsel, Pamuk
Vaccine, ISSN 0264-410X, 07/2019, Volume 37, Issue 32, pp. 4533 - 4542
BM2-deficient | Single replication | Intranasal | Cross-lineage protection | Live influenza | Hemagglutination inhibition | Influenza vaccine | Influenza B | Drifted | Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Influenza vaccines | Prevention | Proteins | Antigens | Medical research | Microbiology | Influenza | Vaccination | Medicine, Experimental | Health aspects | Surface antigens | Mucosa | Antibodies | Viruses | Outbreaks | Infections | Vaccines | Immunity | Experiments | Avian flu | Hemagglutinins | Influenza A | Cytokines | Neutrophils | Feasibility studies | RNA polymerase | Morbidity | Lungs | Plasmids | Replication | Mice | Laboratory animals | Index Medicus | influenza vaccine | hemagglutination inhibition | cross-lineage protection | influenza B | live influenza | drifted | single replication | intranasal
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6. Full Text Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets
by Imai, Masaki and Watanabe, Tokiko and Hatta, Masato and Das, Subash C and Ozawa, Makoto and Shinya, Kyoko and Zhong, Gongxun and Hanson, Anthony and Katsura, Hiroaki and Watanabe, Shinji and Li, Chengjun and Kawakami, Eiryo and Yamada, Shinya and Kiso, Maki and Suzuki, Yasuo and Maher, Eileen A and Neumann, Gabriele and Kawaoka, Yoshihiro
Nature (London), ISSN 0028-0836, 06/2012, Volume 486, Issue 7403, pp. 420 - 428
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics | Microbiology | Virology | Pandemics | Reassortant Viruses - pathogenicity | Influenza A Virus, H5N1 Subtype - physiology | Receptors, Virus - metabolism | Humans | Influenza A Virus, H1N1 Subtype - physiology | Reassortant Viruses - genetics | Reassortant Viruses - physiology | Influenza A Virus, H5N1 Subtype - genetics | Body Fluids - virology | Molecular Epidemiology - methods | Ferrets - virology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Zoonoses - virology | Respiratory System - virology | Adaptation, Physiological - genetics | HEK293 Cells | Female | Influenza, Human - virology | Protein Stability | Influenza A Virus, H1N1 Subtype - genetics | Population Surveillance - methods | Cell Line | Security Measures | Birds - virology | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza in Birds - transmission | Hot Temperature | Influenza, Human - transmission | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Reassortant Viruses - isolation & purification | Respiratory System - anatomy & histology | Zoonoses - transmission | Animals | Receptors, Virus - chemistry | Orthomyxoviridae Infections - transmission | Dogs | Influenza in Birds - virology | Bioterrorism - prevention & control | Influenza A Virus, H5N1 Subtype - pathogenicity | HeLa Cells | Influenza, Human - prevention & control | Orthomyxoviridae Infections - virology | Evolution, Molecular | Prevention | Epidemics | Disease transmission | United States | Japan | Avian influenza viruses | Physiological aspects | Genetic aspects | Research | Host-virus relationships | Ferrets | Cell culture | Task forces | Compliance | Laboratories | RNA polymerase | Academic libraries | Experiments | Avian flu | Proteins | Studies | Swine flu | Plasmids | Risk assessment | Occupational health | Mutation | Index Medicus
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7. Full Text Transmission of SARS-CoV-2 in Domestic Cats
by Sakai-Tagawa, Yuko and Halfmann, Peter J and Takeda, Makoto and Kinoshita, Noriko and Iwatsuki-Horimoto, Kiyoko and Hatta, Masato and Hattori, Shin-ichiro and Chiba, Shiho and Imai, Masaki and Maemura, Tadashi and Kawaoka, Yoshihiro and Fan, Shufang
The New England journal of medicine, ISSN 0028-4793, 08/2020, Volume 383, Issue 6, pp. 592 - 594
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Chlorocebus aethiops | Cats - virology | Immunoglobulin G - blood | Virus Shedding | Antibodies, Viral | Pandemics - veterinary | COVID-19 | Coronavirus Infections - transmission | Pneumonia, Viral - transmission | SARS-CoV-2 | Animals | Coronavirus Infections - veterinary | Pneumonia, Viral - veterinary | Betacoronavirus | Vero Cells | Severe acute respiratory syndrome coronavirus 2 | Cats | Disease transmission | Research & development--R&D | Influenza | Infections | Coronaviruses | Public health | Index Medicus | Abridged Index Medicus
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8. Full Text An M2 cytoplasmic tail mutant as a live attenuated influenza vaccine against pandemic (H1N1) 2009 influenza virus
by Hatta, Yasuko and Hatta, Masato and Bilsel, Pamuk and Neumann, Gabriele and Kawaoka, Yoshihiro
Vaccine, ISSN 0264-410X, 2011, Volume 29, Issue 12, pp. 2308 - 2312
Allergy and Immunology | M2 deletion | Pandemic (H1N1) 2009 | Live attenuated vaccine | Influenza vaccine | Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Fundamental and applied biological sciences. Psychology | Miscellaneous | Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) | Microbiology | Applied microbiology | Biological and medical sciences | Virology | Influenza A Virus, H1N1 Subtype - immunology | Orthomyxoviridae Infections - prevention & control | Viral Matrix Proteins - genetics | Humans | Virulence | Influenza A Virus, H1N1 Subtype - pathogenicity | Antibodies, Viral - blood | Vaccines, Attenuated - immunology | Animals | Influenza Vaccines - immunology | Dogs | HEK293 Cells | Antibodies, Viral - immunology | Female | Mice | Mice, Inbred BALB C | Viral Matrix Proteins - immunology | Virus Cultivation | Mutation | Influenza A Virus, H1N1 Subtype - genetics | Orthomyxoviridae Infections - immunology | Enzymes | Cell culture | Pandemics | Viruses | Amino acids | Infections | Vaccines | RNA polymerase | Avian flu | Proteins | Lungs | Plasmids | Drug dosages | Index Medicus
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9. Full Text Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus
by Hatta, Masato and Shinya, Kyoko and Suzuki, Hiroshi and Kobasa, Darwyn and Takada, Ayato and Kawaoka, Yoshihiro and Usui, Taichi and Nishimura, Hidekazu and Mitamura, Keiko and Watanabe, Shinji and Halfmann, Peter and Feldmann, Heinz and Suzuki, Takashi and Theriault, Steven and Murata, Takeomi and Sugaya, Norio and Suzuki, Yasuo and Suresh, M and Maeda, Yasuko
Nature, ISSN 0028-0836, 10/2004, Volume 431, Issue 7009, pp. 703 - 707
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Influenza, Human - pathology | Virulence Factors - genetics | Humans | Influenza A virus - genetics | Middle Aged | Child, Preschool | Neuraminidase - genetics | Infant | Neutralization Tests | Influenza, Human - complications | Hemagglutinin Glycoproteins, Influenza Virus - immunology | Hemagglutinin Glycoproteins, Influenza Virus - genetics | Neuraminidase - immunology | Lung - virology | Time Factors | Virulence - genetics | Genes, Viral - genetics | Aged, 80 and over | Influenza A virus - pathogenicity | Recombination, Genetic - genetics | Adult | Influenza A virus - immunology | Influenza, Human - virology | Child | Hemorrhage - virology | Binding, Competitive | Cell Line | Immune Sera - immunology | Lung - pathology | Hemorrhage - complications | Neuraminidase - metabolism | Influenza, Human - epidemiology | Hemagglutinin Glycoproteins, Influenza Virus - metabolism | Animals | Genetic Engineering | Adolescent | Dogs | Antibodies, Viral - immunology | Virulence Factors - metabolism | Aged | Mice | Hemorrhage - pathology | Proteins | Genetic research | Viruses | Pandemics | Influenza | Genes | Index Medicus
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10. Full Text Impact of Amino Acid Mutations in PB2, PB1-F2, and NS1 on the Replication and Pathogenicity of Pandemic (H1N1) 2009 Influenza Viruses
by Makoto Ozawa and Sarmila Basnet and Lisa M. Burley and Gabriele Neumann and Masato Hatta and Yoshihiro Kawaoka
Journal of Virology, ISSN 0022-538X, 05/2011, Volume 85, Issue 9, pp. 4596 - 4601
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Replicative cycle, interference, host-virus relations, pathogenicity, miscellaneous strains | Biological and medical sciences | Miscellaneous | Microbiology | Orthomyxoviridae Infections - pathology | Virulence | Viral Nonstructural Proteins - genetics | Viral Proteins - genetics | Influenza A Virus, H1N1 Subtype - pathogenicity | Viral Proteins - metabolism | Animals | Influenza A Virus, H1N1 Subtype - isolation & purification | Virus Replication | Amino Acid Substitution - genetics | Viral Nonstructural Proteins - metabolism | Mice | Influenza A Virus, H1N1 Subtype - genetics | Orthomyxoviridae Infections - virology | Index Medicus | Pathogenesis and Immunity
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