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1. Full Text Acute lung injury in patients with severe brain injury: A double hit model
by Mascia, Luciana
Neurocritical Care, ISSN 1541-6933, 01/2009, Volume 11, Issue 3, pp. 417 - 426
The presence of pulmonary dysfunction after brain injury is well recognized. Acute lung injury (ALI) occurs in 20% of patients with isolated brain injury and... 
Acute lung injury | Traumatic brain injury | Subarachnoid hemorrhage | Mechanical ventilation | ANEURYSMAL SUBARACHNOID HEMORRHAGE | CEREBRAL PERFUSION-PRESSURE | RANDOMIZED CONTROLLED-TRIAL | BLOOD-FLOW | CLINICAL NEUROLOGY | RESPIRATORY-DISTRESS-SYNDROME | END-EXPIRATORY PRESSURE | SEVERE HEAD-INJURY | NEUROGENIC PULMONARY-EDEMA | INTRACRANIAL-PRESSURE | CRITICAL CARE MEDICINE | Pulmonary Edema - physiopathology | Acute Lung Injury - physiopathology | Pulmonary Edema - therapy | Prognosis | Acute Lung Injury - therapy | Models, Biological | Humans | Brain Injuries - complications | Brain Injuries - physiopathology | Acute Lung Injury - etiology | Pulmonary Edema - etiology | Respiration, Artificial | Acute respiratory distress syndrome | Brain | Care and treatment | Permeability | Injuries
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2. Full Text ECMO criteria for influenza A (H1N1)-associated ARDS: role of transpulmonary pressure
by Grasso, Salvatore and Terragni, Pierpaolo and Birocco, Alberto and Urbino, Rosario and Del Sorbo, Lorenzo and Filippini, Claudia and Mascia, Luciana and Pesenti, Antonio and Zangrillo, Alberto and Gattinoni, Luciano and Ranieri, V Marco
Intensive Care Medicine, ISSN 0342-4642, 3/2012, Volume 38, Issue 3, pp. 395 - 403
To assess whether partitioning the elastance of the respiratory system (E RS) between lung (E L) and chest wall (E CW) elastance in order to target values of... 
Pediatrics | Pain Medicine | Transpulmonary pressure | Extracorporeal membrane oxygenation | Emergency Medicine | Pneumology/Respiratory System | Medicine & Public Health | Influenza A (H1N1) | Intensive / Critical Care Medicine | Anesthesiology | ARDS | A(H1N1) SUFFICIENT EVIDENCE | LOWER INFLECTION POINT | MECHANICAL VENTILATION | ACUTE LUNG INJURY | RANDOMIZED CONTROLLED-TRIAL | RESPIRATORY-DISTRESS-SYNDROME | CHEST-WALL | END-EXPIRATORY PRESSURE | EXTRACORPOREAL MEMBRANE-OXYGENATION | RECRUITMENT MANEUVERS | CRITICAL CARE MEDICINE | Humans | Influenza A Virus, H1N1 Subtype | Extracorporeal Membrane Oxygenation - standards | Italy | Influenza, Human - complications | Positive-Pressure Respiration - methods | Influenza, Human - therapy | Positive-Pressure Respiration - standards | Respiratory Distress Syndrome, Adult - etiology | Respiratory Distress Syndrome, Adult - therapy | Acute respiratory distress syndrome | Care and treatment | Blood oxygenation, Extracorporeal | Influenza | Causes of | Research | Health aspects
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3. Full Text Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
by Maas, Andrew I R and Menon, David K and Adelson, P David and Andelic, Nada and Bell, Michael J and Belli, Antonio and Bragge, Peter and Brazinova, Alexandra and Büki, András and Chesnut, Randall M and Citerio, Giuseppe and Coburn, Mark and Cooper, D Jamie and Crowder, A Tamara and Czeiter, Endre and Czosnyka, Marek and Diaz-Arrastia, Ramon and Dreier, Jens P and Duhaime, Ann-Christine and Ercole, Ari and van Essen, Thomas A and Feigin, Valery L and Gao, Guoyi and Giacino, Joseph and Gonzalez-Lara, Laura E and Gruen, Russell L and Gupta, Deepak and Hartings, Jed A and Hill, Sean and Jiang, Ji-yao and Ketharanathan, Naomi and Kompanje, Erwin J O and Lanyon, Linda and Laureys, Steven and Lecky, Fiona and Levin, Harvey and Lingsma, Hester F and Maegele, Marc and Majdan, Marek and Manley, Geoffrey and Marsteller, Jill and Mascia, Luciana and McFadyen, Bradford and McFadyen, Charles and Mondello, Stefania and Newcombe, Virginia and Palotie, Aarno and Parizel, Paul M and Peul, Wilco and Piercy, James and Polinder, Suzanne and Puybasset, Louis and Rasmussen, Todd E and Rossaint, Rolf and Smielewski, Peter and Söderberg, Jeannette and Stanworth, Simon J and Stein, Murray B and von Steinbüchel, Nicole and Stewart, William and Steyerberg, Ewout W and Stocchetti, Nino and Synnot, Anneliese and Te Ao, Braden and Tenovuo, Olli and Theadom, Alice and Tibboel, Dick and Videtta, Walter and Wang, Kevin K W and Williams, W Huw and Williams, Guy and Wilson, Lindsay and Yaffe, Kristine and Adams, Hadie and Agnoletti, Vanni and Allanson, Judith and Amrein, Krisztina and Andaluz, Norberto and Anke, Audny and Antoni, Anna and van As, Arjan Bastiaan and Audibert, Gérard and Azaševac, Antun and Azouvi, Philippe and Azzolini, Maria Luisa and Baciu, Camelia and Badenes, Rafael and Barlow, Karen M and Bartels, Ronald and Bauerfeind, Ursula and Beauchamp, Miriam and Beer, Darcy and Beer, Ronny and Belda, Francisco Javier and Bellander, Bo-Michael and Bellier, Rémy and Benali, Habib and Benard, Thierry and Beqiri, Valzerda and Beretta, Luigi and ... and InTBIR Participants Investigators and InTBIR Participants and Investigators
The Lancet Neurology, ISSN 1474-4422, 12/2017, Volume 16, Issue 12, pp. 987 - 1048
[...]it might also be possible to specifically target individuals to address their patterns of risk-taking behaviour.183 Irrespective of the target population,... 
DIAGNOSTIC MANAGEMENT STRATEGIES | UNITED-STATES | EMERGENCY-DEPARTMENT VISITS | ACUTE SUBDURAL-HEMATOMA | GLASGOW COMA SCALE | MILD HEAD-INJURY | RANDOMIZED CONTROLLED-TRIAL | HIGH-SCHOOL FOOTBALL | CLINICAL NEUROLOGY | PATIENT-REPORTED OUTCOMES | EVIDENCE-BASED MEDICINE | Brain Injuries, Traumatic - prevention & control | Brain Injuries, Traumatic - therapy | Brain Injuries - etiology | Brain Injuries, Traumatic - epidemiology | Humans | Brain Injuries - prevention & control | Nuclear magnetic resonance--NMR | Traumatic brain injury | Mortality | Health care policy | Patients | Trauma | Epidemiology | Evidence-based medicine | Medicine | Consortia | Disease prevention | Disability | Brain research | Researchers | Research methodology | Trauma centers | Clinical medicine | Public health
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4. Full Text Early vs Late Tracheotomy for Prevention of Pneumonia in Mechanically Ventilated Adult ICU Patients: A Randomized Controlled Trial
by Terragni, Pier Paolo and Antonelli, Massimo and Fumagalli, Roberto and Faggiano, Chiara and Berardino, Maurizio and Pallavicini, Franco Bobbio and Miletto, Antonio and Mangione, Salvatore and Sinardi, Angelo U and Pastorelli, Mauro and Vivaldi, Nicoletta and Pasetto, Alberto and Della Rocca, Giorgio and Urbino, Rosario and Filippini, Claudia and Pagano, Eva and Evangelista, Andrea and Ciccone, Gianni and Mascia, Luciana and Ranieri, V. Marco
JAMA, ISSN 0098-7484, 04/2010, Volume 303, Issue 15, pp. 1483 - 1489
CONTEXT Tracheotomy is used to replace endotracheal intubation in patients requiring prolonged ventilation; however, there is considerable variability in the... 
SURGICAL TRACHEOSTOMY | DIAGNOSIS | MEDICINE, GENERAL & INTERNAL | SCORE | METAANALYSIS | INTUBATION | INTENSIVE-CARE-UNIT | PERCUTANEOUS TRACHEOSTOMY | TRANSLARYNGEAL | CRITICALLY-ILL PATIENTS | RESPIRATORY-DISTRESS-SYNDROME | Length of Stay | Intensive Care Units | Humans | Middle Aged | Pneumonia, Ventilator-Associated - prevention & control | Male | Tracheotomy | Respiration, Artificial - adverse effects | Time Factors | Adult | Female | Italy | Aged | Disease prevention | Intensive care | Pneumonia | Intubation | Patients
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5. Full Text Effect of a Lung Protective Strategy for Organ Donors on Eligibility and Availability of Lungs for Transplantation: A Randomized Controlled Trial
by Mascia, Luciana and Pasero, Daniela and Slutsky, Arthur S and Arguis, M. Jose and Berardino, Maurizio and Grasso, Salvatore and Munari, Marina and Boifava, Silvia and Cornara, Giuseppe and Della Corte, Francesco and Vivaldi, Nicoletta and Malacarne, Paolo and Del Gaudio, Paolo and Livigni, Sergio and Zavala, Elisabeth and Filippini, Claudia and Martin, Erica L and Donadio, Pier Paolo and Mastromauro, Ilaria and Ranieri, V. Marco
JAMA, ISSN 0098-7484, 12/2010, Volume 304, Issue 23, pp. 2620 - 2627
CONTEXT Many potential donor lungs deteriorate between the time of brain death and evaluation for transplantation suitability, possibly because of the... 
MEDICINE, GENERAL & INTERNAL | MANAGEMENT | VENTILATION | BRAIN-INJURY | MODEL | SELECTION | RESPIRATORY-DISTRESS-SYNDROME | Single-Blind Method | Suction | Donor Selection | Humans | Middle Aged | Male | Lung - physiopathology | Positive-Pressure Respiration | Lung Transplantation | Apnea - diagnosis | Survival Analysis | Adult | Female | Tissue Donors | Eligibility Determination | Clinical trials | Blood & organ donations | Transplants & implants | Lungs | Brain death
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6. Full Text A fixed correction of absolute transpulmonary pressure may not be ideal for clinical use : Discussion on "Accuracy of esophageal pressure to assess transpulmonary pressure during mechanical ventilation"
by Baedorf Kassis, Elias and Loring, Stephen H and Talmor, Daniel and Terragni, Pierpaolo and Mascia, Luciana and Ranieri, V Marco
Intensive care medicine, ISSN 0342-4642, 09/2017, Volume 43, Issue 9, p. 1436
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s00134-017-4823-z 
Usage | Research | Artificial respiration | Methods
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7. Full Text Acute Tubular Injury is Associated With Severe Traumatic Brain Injury: in Vitro Study on Human Tubular Epithelial Cells
by Civiletti, F and Assenzio, B and Mazzeo, AT and Medica, D and Giaretta, F and Deambrosis, I and Fanelli, V and Ranieri, VM and Cantaluppi, V and Mascia, L
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 6090 - 11
Acute kidney injury following traumatic brain injury is associated with poor outcome. We investigated in vitro the effects of plasma of brain injured patients... 
ACUTE KIDNEY INJURY | CYTOKINES | ACTIVATION | INTERCELLULAR-ADHESION MOLECULE-1 | ICAM-1 EXPRESSION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | INVOLVEMENT | NEUROLOGICAL ORGAN DYSFUNCTION | INTENSIVE-CARE | EXTRACRANIAL COMPLICATIONS | Coma | Creatinine | Urine | Phenotypes | Kidneys | Traumatic brain injury | Epithelial cells | Lipocalin | Neutrophils | Cytotoxicity | Leukocytes (neutrophilic) | Inflammation | Gelatinase | Trauma | Vitamin A | Immunoelectrophoresis | Apoptosis
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8. Full Text Accuracy of esophageal pressure to assess transpulmonary pressure during mechanical ventilation
by Terragni, Pierpaolo and Mascia, Luciana and Fanelli, Vito and Biondi-Zoccai, Giuseppe and Ranieri, V Marco
Intensive Care Medicine, ISSN 0342-4642, 1/2017, Volume 43, Issue 1, pp. 142 - 143
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1007/s00134-016-4589-8 
Pediatrics | Pain Medicine | Emergency Medicine | Pneumology/Respiratory System | Medicine & Public Health | Intensive / Critical Care Medicine | Anesthesiology | CRITICAL CARE MEDICINE | Respiration, Artificial - methods | Humans | Monitoring, Physiologic - methods | Esophagus - physiology | Tidal Volume | Positive-Pressure Respiration | Pulmonary Artery - physiology
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9. Full Text Tidal volume lower than 6 ml/kg enhances lung protection: Role of extracorporeal carbon dioxide removal
by Ranieri, V. Marco and Terragni, Pier Paolo and Del Sorbo, Lorenzo and Mascia, Luciana and Urbino, Rosario and Martin, Erica L and Birocco, Alberto and Faggiano, Chiara and Quintel, Michael and Gattinoni, Luciano
Anesthesiology, ISSN 0003-3022, 2009, Volume 111, Issue 4, pp. 826 - 835
Background: Tidal hyperinflation may occur in patients with acute respiratory distress syndrome who are ventilated with a tidal volume (V-T) of 6 ml/kg of... 
END-EXPIRATORY PRESSURE | LIFE-SUPPORT | CLINICAL-TRIAL | CO2 REMOVAL | MECHANICAL VENTILATION | INJURY | ANESTHESIOLOGY | PERMISSIVE HYPERCAPNIA | POSITIVE-PRESSURE VENTILATION | MEMBRANE-OXYGENATION | RESPIRATORY-DISTRESS-SYNDROME | Cardiac Output - physiology | Lung - pathology | Humans | Lung Diseases - prevention & control | Middle Aged | Pneumonia - pathology | Air Pressure | Carbon Dioxide - isolation & purification | Male | Tomography, X-Ray Computed | Lung - diagnostic imaging | Carbon Dioxide - blood | Positive-Pressure Respiration | Extracorporeal Membrane Oxygenation | Respiration, Artificial - adverse effects | Female | Acidosis, Respiratory - therapy | Aged | Lung Diseases - pathology | Respiratory Function Tests | Cytokines - blood | Hydrogen-Ion Concentration | Respiratory Distress Syndrome, Adult - therapy | Tidal Volume - physiology
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10. Full Text Being overweight or obese is associated with decreased mortality in critically ill patients: A retrospective analysis of a large regional Italian multicenter cohort
by Sakr, Yasser, MD, PhD and Elia, Cristina, MD and Mascia, Luciana, MD, PhD and Barberis, Bruno, MD and Cardellino, Silvano, MD and Livigni, Sergio, MD and Fiore, Gilberto, MD and Filippini, Claudia and Ranieri, V. Marco, MD, PhD
Journal of Critical Care, ISSN 0883-9441, 2012, Volume 27, Issue 6, pp. 714 - 721
Abstract Purpose To describe the epidemiology of obesity in a large cohort of intensive care unit (ICU) patients and study its impact on outcomes. Methods All... 
Critical Care | Prognosis | Critically ill patients | BMI | METAANALYSIS | GUIDELINES | ADULTS | ACUTE LUNG INJURY | SLEEP-APNEA | RISK | PARADOX | INTENSIVE-CARE-UNIT | BODY-MASS INDEX | OUTCOMES | CRITICAL CARE MEDICINE | Thinness - mortality | Age Factors | Humans | Middle Aged | Intensive Care Units - statistics & numerical data | Male | Critical Illness - mortality | Multicenter Studies as Topic | Overweight - epidemiology | Aged, 80 and over | Adult | Female | Retrospective Studies | Obesity - mortality | Overweight - mortality | Body Mass Index | Comorbidity | Sepsis - epidemiology | Sepsis - mortality | Thinness - epidemiology | Obesity - epidemiology | Sex Factors | Italy - epidemiology | Aged | Obesity | Mortality | Analysis | Patient outcomes
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