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Chemical Communications, ISSN 1359-7345, 06/2015, Volume 51, Issue 46, pp. 9436 - 9439
Journal Article
Journal Article
Journal of Inorganic Biochemistry, ISSN 0162-0134, 09/2019, Volume 198, pp. 110714 - 110714
A micro-electrochemical reaction cell was coupled to an electrospray mass spectrometer in order to track redox transformations for two representative medicinal... 
Electrochemical cell | Cytotoxic gold complexes | Voltammetry | Prodrug | Metallodrug | Electrospray MS
Journal Article
Journal Article
European Journal of Inorganic Chemistry, ISSN 1434-1948, 03/2017, Volume 2017, Issue 12, pp. 1737 - 1744
AuL10 ([Au III Cl 2 (dmdt)], dmdt = N , N ‐dimethyldithiocarbamate) and AuL12 ([Au III Br 2 (esdt)], esdt = ethylsarcosine dithiocarbamate) are two extremely... 
Gold | Reduction | Antitumor agents | Metallodrugs | Biological activity | RECOGNITION | HUMAN SERUM-ALBUMIN | COMPOUND | GOLD COMPLEXES | CHEMISTRY, INORGANIC & NUCLEAR | SOLUTION CHEMISTRY | DNA | AURANOFIN | AGENTS | CYTOTOXICITY | DERIVATIVES | Lung cancer, Non-small cell | Cytokinins | Analysis | Microelectrodes | Biomolecules | Systems analysis | Impedance | Real time | Anticancer properties | Cancer
Journal Article
ISSN 1359-7345, 5/2015, Volume 51, Issue 46, pp. 9436 - 9439
The reaction between cisplatin and human serum albumin (HSA) was investigated by X-ray crystallography and crystal structures of the cisplatin/HSA adduct were... 
Journal Article
Biometals, ISSN 0966-0844, 08/2019, pp. 1 - 5
The study of metal-based drugs represents an important branch of modern bioinorganic chemistry. The growing importance of this field is linked to the large... 
Drugs | Gold | Ruthenium | Metals | Thimerosal | Phenylmercury | Cisplatin | Organic chemistry | Researchers | Oxaliplatin | Sodium | Platinum | Carboplatin | Acetic acid | Mercury | Mercury (metal) | Index Medicus
Journal Article
Dalton Transactions, ISSN 1477-9226, 2016, Volume 45, Issue 20, pp. 8587 - 8600
Contrary to what was believed for many years, cis-PtI2(NH3)2, the diiodido analogue of cisplatin, displays high in vitro antiproliferative activity toward a... 
Index Medicus | Biotechnology | Deoxyribonucleic acid | Strands | Oligonucleotides | Dichroism | Control systems | Displays | Derivatives
Journal Article
BioMetals, ISSN 0966-0844, 02/2019, Volume 32, Issue 1, p. 33
A series of palladium(II) (1--3) and platinum(II) chloride complexes (4 and 5) with 2,2 :6 ,2a[sup.3]-terpyridine (terpy) derivatives substituted at the 4... 
Cytochrome c | Biotechnology | Analysis | Lung cancer | Colorectal cancer | Palladium | Biochemistry | Ribonuclease | Lysozyme | Protein binding | Ovarian cancer
Journal Article
BioMetals, ISSN 0966-0844, 4/2017, Volume 30, Issue 2, pp. 313 - 320
Gold compounds form a new class of promising metal-based drugs with a number of potential therapeutic applications, particularly in the fields of anticancer... 
Biochemistry, general | Life Sciences | Cysteine proteases | Gold compounds | Microbiology | Enzyme inhibition | Plant Physiology | Parasitic protozoa | Pharmacology/Toxicology | Medicine/Public Health, general | Cell Biology | DRUG-SENSITIVITY | TRYPANOSOMA-BRUCEI-RHODESIENSE | ASSAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEXES | IN-VITRO | LEISHMANIA-MEXICANA | CATHEPSIN-L | ROLES | PARASITE | Cysteine Endopeptidases - chemistry | Plasmodium falciparum - enzymology | Fibroblasts - enzymology | Protozoan Proteins - antagonists & inhibitors | Humans | Cathepsin B - chemistry | Plasmodium falciparum - drug effects | Trypanosoma brucei brucei - enzymology | Trypanosoma cruzi - enzymology | Leishmania infantum - growth & development | Cysteine Proteinase Inhibitors - chemical synthesis | Inhibitory Concentration 50 | Trypanosoma brucei rhodesiense - growth & development | Antiprotozoal Agents - chemical synthesis | Protozoan Proteins - chemistry | Trypanosoma brucei brucei - growth & development | Cell Line | Organogold Compounds - chemical synthesis | Cathepsin B - antagonists & inhibitors | Proteasome Endopeptidase Complex - chemistry | Recombinant Proteins - chemistry | Macrophages - cytology | Cathepsin L - antagonists & inhibitors | Antiprotozoal Agents - pharmacology | Trypanosoma brucei brucei - drug effects | Leishmania infantum - enzymology | Macrophages - enzymology | Animals | Trypanosoma cruzi - growth & development | Organogold Compounds - pharmacology | Cysteine Proteinase Inhibitors - pharmacology | Fibroblasts - drug effects | Leishmania infantum - drug effects | Trypanosoma cruzi - drug effects | Macrophages - drug effects | Fibroblasts - cytology | Mice | Trypanosoma brucei rhodesiense - drug effects | Plasmodium falciparum - growth & development | Cathepsin L - chemistry | Trypanosoma brucei rhodesiense - enzymology | Cysteine | Biological products | Protease inhibitors | Proteases | Parasitic diseases | Antiparasitic agents | Technical education | Cystine | Gold | Enzymes | Antimicrobial agents | Cancer therapies | Pharmaceuticals | Index Medicus
Journal Article
Inorganica Chimica Acta, ISSN 0020-1693, 09/2019, Volume 495, p. 118983
Since the first approval of cisplatin for cancer treatment in 1978, a lot of attempts have been carried out to characterize in detail its interactions with... 
Human Serum Albumin | Metalation sites | Mass spectrometry | Cisplatin | Crystal structure | Human serum albumin | ANTICANCER DRUG CISPLATIN | HUMAN SERUM-ALBUMIN | BLOOD-PLASMA | COMPLEXES | PROTEIN-BINDING | MASS-SPECTROMETRY | CHEMISTRY, INORGANIC & NUCLEAR | LIQUID-CHROMATOGRAPHY | METABOLISM | BINDING-SITES | CYTOTOXICITY
Journal Article
Journal Article
by Chatrchyan, S and Khachatryan, V and Sirunyan, A.M and Tumasyan, A and Adam, N and Adam, W and Aguilo, E and Bergauer, T and Dragicevic, M and Erö, J and Fabjan, C and Friedl, M and Frühwirth, R and Ghete, V.M and Hammer, J and Hoch, M and Hörmann, N and Hrubec, J and Jeitler, M and Kiesenhofer, W and Knünz, V and Krammer, M and Krätschmer, I and Liko, D and Majerotto, W and Mikulec, I and Pernicka, M and Rahbaran, B and Rohringer, H and Rohringer, C and Schöfbeck, R and Strauss, J and Szoncsó, F and Taurok, A and Waltenberger, W and Walzel, G and Widl, E and Wulz, C.-E and Chekhovsky, V and Emeliantchik, I and Litomin, A and Makarenko, V and Mossolov, V and Shumeiko, N and Solin, A and Stefanovitch, R and Suarez Gonzalez, J and Fedorov, A and Korzhik, M and Missevitch, O and Zuyeuski, R and Bansal, M and Bansal, S and Beaumont, W and Cornelis, T and De Wolf, E.A and Druzhkin, D and Janssen, X and Luyckx, S and Mucibello, L and Ochesanu, S and Roland, B and Roland, C and Roland, G and Rougny, R and Selvaggi, G and Selvaggi, M and Staykova, Z and Van Haevermaet, H and Van Mechelen, P and Van Remortel, N and Van Spilbeeck, A and Blekman, F and Blyweert, S and DʼHondt, J and Devroede, O and Gonzalez Suarez, R and Goorens, R and Kalogeropoulos, A and Maes, M and Olbrechts, A and Tavernier, S and Van Doninck, W and Van Lancker, L and Van Mulders, P and Van Onsem, G.P and Villella, I and Clerbaux, B and De Lentdecker, G and Dero, V and Dewulf, J.P and Gay, A.P.R and Hreus, T and Léonard, A and Marage, P.E and Mohammadi, A and Reis, T and Rugovac, S and Thomas, S and Thomas, M and ... and CMS Collaboration and Los Alamos National Lab. (LANL), Los Alamos, NM (United States) and Argonne National Lab. (ANL), Argonne, IL (United States) and Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States) and Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Physics Letters B, ISSN 0370-2693, 09/2012, Volume 716, Issue 1, pp. 30 - 61
Journal Article