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Journal Article
PLoS Computational Biology, ISSN 1553-734X, 09/2017, Volume 13, Issue 9, pp. e1005709 - e1005709
Journal Article
Circulation Research, ISSN 0009-7330, 02/2017, Volume 120, Issue 4, pp. 604 - 606
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2018, Volume 115, Issue 3, pp. E363 - E371
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/2011, Volume 300, Issue 2, pp. 448 - 458
The differentiation of valvular interstitial cells (VICs) to a myofibroblastic or osteoblast-like phenotype is commonly found in calcific valvular stenosis,... 
Signaling pathways | Extracellular matrix | Nodule formation | Heart valve | Myofibroblast | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | myofibroblast | heart valve | PROTEIN-KINASE | AORTIC-VALVE CALCIFICATION | VASCULAR SMOOTH-MUSCLE | GROWTH-FACTOR-BETA | IN-VITRO | signaling pathways | HEART-VALVES | BONE-FORMATION | nodule formation | PERIPHERAL VASCULAR DISEASE | EXTRACELLULAR-MATRIX | extracellular matrix | CARDIAC VALVES | Calcinosis - genetics | Immunohistochemistry | Cell Proliferation | Heart Valve Diseases - pathology | Apoptosis - drug effects | Actins - metabolism | Apoptosis - genetics | RNA - isolation & purification | rho-Associated Kinases - metabolism | Swine | Calcinosis - drug therapy | Enzyme-Linked Immunosorbent Assay | Heart Valves - physiology | Cells, Cultured | Reverse Transcriptase Polymerase Chain Reaction | rho GTP-Binding Proteins - physiology | Stimulation, Chemical | RNA - biosynthesis | Phenotype | Animals | Signal Transduction - drug effects | Heart Valve Diseases - genetics | Signal Transduction - physiology | Heart Valve Diseases - drug therapy | Calcinosis - pathology | Heart Valves - cytology | Microscopy, Fluorescence | Heart cells | Physiological aspects | Genetic aspects | Chemical properties | Gene expression | Phosphotransferases | Heart valves | Genotype & phenotype | Molecules | Medical treatment | Kinases | Cells | Apoptosis | Index Medicus | Vascular Biology and Microcirculation
Journal Article
Journal Article
Journal of Biomedical Materials Research Part A, ISSN 1549-3296, 10/2013, Volume 101, Issue 10, pp. 2870 - 2882
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 06/2009, Volume 296, Issue 6, pp. 1748 - 1757
Much remains to be discovered about the etiology of heart valve disease and the molecular level mechanisms that drive it. The MAPK/ERK pathway influences... 
Signaling pathways | Extracellular matrix | Heart valve | Mineralization | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | ACTIVATED PROTEIN-KINASE | heart valve | CALCIFYING VASCULAR CELLS | OSTEOBLASTIC DIFFERENTIATION | OSTEOGENIC DIFFERENTIATION | AORTIC-VALVE CALCIFICATION | MYOFIBROBLAST ACTIVATION | mineralization | signaling pathways | BONE-FORMATION | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | EXTRACELLULAR-MATRIX | extracellular matrix | CARDIAC VALVES | MAP Kinase Signaling System - physiology | Heart Valve Diseases - pathology | Nitriles - pharmacology | Cell Count | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | Extracellular Matrix - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | Cell Movement - physiology | Swine | Gene Expression - physiology | Flavonoids - pharmacology | Calcinosis - metabolism | MAP Kinase Kinase 1 - antagonists & inhibitors | Butadienes - pharmacology | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Tissue Culture Techniques | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | MAP Kinase Kinase 1 - metabolism | MAP Kinase Kinase 2 - metabolism | Phenotype | Animals | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | MAP Kinase Kinase 2 - antagonists & inhibitors | Heart Valve Diseases - metabolism | Biomarkers | Apoptosis - physiology | Calcinosis - pathology | Mitogen-Activated Protein Kinase 1 - metabolism | Heart | Abdominal surgery | Genotype & phenotype | Calcium | Cardiovascular disease | Cells | Apoptosis | Index Medicus
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/2015, Volume 137, Issue 6, pp. 2183 - 2186
Journal Article