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Scientific Reports, ISSN 2045-2322, 12/2019, Volume 9, Issue 1, pp. 1211 - 13
Homozygous mutations in SNAP29, encoding a SNARE protein mainly involved in membrane fusion, cause CEDNIK (Cerebral Dysgenesis, Neuropathy, Ichthyosis and... 
CONSERVATION | BIOGENESIS | BDNF | VESICLES | MULTIDISCIPLINARY SCIENCES | MOTOR | TRAFFICKING | PHENOTYPE | DISORDERS | AUTOPHAGY | SYNTAXIN 17 | Membrane fusion | Pathogenesis | SNAP receptors | Neuropathy | Neurodevelopmental disorders | Organelles | Autophagy | Ichthyosis | Membrane proteins | Mitochondria | Microencephaly | Life span | Trigeminal nerve | Cell death | Genetic analysis | Cerebrum | SNAP-25 protein | Phagocytosis | Apoptosis
Journal Article
The FEBS Journal, ISSN 1742-464X, 06/2018, Volume 285, Issue 11, pp. 2104 - 2124
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers. Its aggressiveness is driven by an intense fibrotic desmoplastic reaction in which... 
pancreatic adenocarcinoma | VEFGR‐2 | cancer stem cells | vasculogenic mimicry | 3D organotypic cultures | desmoplastic reaction | VEFGR-2 | PANCREATIC DUCTAL ADENOCARCINOMA | METASTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | 3D CULTURE | PHENOTYPE | DESMOPLASIA | STROMAL BIOLOGY | GROWTH | CANCER PROGRESSION | TUMOR MICROENVIRONMENT | Adenocarcinoma - pathology | Neoplastic Stem Cells - drug effects | Humans | Vascular Endothelial Growth Factor A - genetics | Carcinoma, Pancreatic Ductal - genetics | Neovascularization, Pathologic - pathology | Vascular Endothelial Growth Factor Receptor-2 - genetics | Extracellular Matrix - genetics | Neoplasm Metastasis | Tumor Microenvironment - genetics | Neoplasm Invasiveness - pathology | Neoplastic Stem Cells - pathology | Adenocarcinoma - genetics | Cell Culture Techniques | Gene Expression Regulation, Neoplastic - drug effects | Parenchymal Tissue - drug effects | Extracellular Matrix - drug effects | Parenchymal Tissue - pathology | Carcinoma, Pancreatic Ductal - pathology | Cell Plasticity - genetics | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Cell Proliferation - drug effects | Collagen Type I - pharmacology | Neoplasm Invasiveness - genetics | Vascular endothelial growth factor | Collagen | Pancreatic cancer | Stem cells | Adenocarcinoma | Phenotypes | Collagen (type I) | Composition | Invasiveness | Collagens | Stroma | Secretome | Mimicry | Metastases | Vascular endothelial growth factor receptors | Angiogenesis | Laminin | Fibrosis | Extracellular matrix | Infiltration | Pancreas | Tumors
Journal Article
Seminars in Cell and Developmental Biology, ISSN 1084-9521, 02/2018, Volume 74, pp. 29 - 39
ESCRT (Endosomal Sorting Complex Required for Transport) proteins have been shown to control an increasing number of membrane-associated processes. Some of... 
Signaling | Endocytosis | Human disease | ESCRT | Vps genes | Notch | Development | Endosome | GIANT DISCS | ENDOCYTIC PATHWAY | PREVACUOLAR COMPARTMENT | NOTCH ACTIVATION | DOWN-REGULATION | DEVELOPMENTAL BIOLOGY | CELL-DEATH | CELL BIOLOGY | ENDOSOMAL TRAFFICKING | DEUBIQUITINATING ENZYME AMSH3 | SORTING COMPLEX | III COMPLEX
Journal Article
Autophagy, ISSN 1554-8627, 12/2014, Volume 10, Issue 12, pp. 2251 - 2268
How autophagic degradation is linked to endosomal trafficking routes is little known. Here we screened a collection of uncharacterized Drosophila mutants... 
Socs36E, suppressor of cytokine signaling at 36E | Vps25, vacuolar protein sorting 25 | dome | ESCRT, endosomal sorting complex required for transport | Syb, Synaptobrevin | hop-Stat92E, hopscotch-signal transducer and activator of transcription protein at 92E | SNARE | EM, electron microscopy | FE, follicular epithelium | usnp | CEDNIK, cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma | V-ATPase, vacuolar H | dome, domeless | NECD, N extracellular domain | Vamp, vesicle-associated membrane protein | trafficking | N, Notch | CFP, cyan fluorescent protein | Atg, autophagy-related | GFP, green fluorescent protein | autophagy | MENE, mutant eye no eclosion | ATPase | Notch | WT, wild type | refP, refractory to sigma P | MVB, multivesicular body | + | Snap29 | NPF, asparagine-proline-phenylalanine | SNARE, soluble NSF attachment protein receptor | os, outstretched | E(spl)mβ-HLH, enhancer of split mβ, helix-loop-helix | Syx, syntaxin | histone H3, His3 | Snap29, synaptosomal-associated protein 29 kDa | Dome | Trafficking | Usnp | Autophagy | ACTIVATION | FUSION | ATPASE | COMPLEX GENES | CELL BIOLOGY | GENETIC SCREEN | SNAP-29 | PATHWAY | NOTCH RECEPTOR | UNCONVENTIONAL SECRETION | MELANOGASTER | Exosomes - metabolism | Vesicular Transport Proteins - metabolism | Humans | Phagosomes - metabolism | Qb-SNARE Proteins - metabolism | Protein Transport - physiology | Autophagy - physiology | Drosophila Proteins - metabolism | Cell Movement - physiology | Endosomes - metabolism | Drosophila melanogaster - metabolism | Animals | Qc-SNARE Proteins - metabolism | SNARE Proteins - metabolism | Protein Binding - physiology
Journal Article
Cell stress, ISSN 2523-0204, 03/2018, Volume 2, Issue 4, pp. 72 - 81
Despite extensive study, regulation of membrane trafficking is incompletely understood. In particular, the specific role of SNARE (Soluble NSF Attachment... 
autophagy | SNARE proteins | cell division | endocytosis | membrane trafficking | SNAP family | Snap29
Journal Article
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