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Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 02/2019, Volume 83, Issue 2, pp. 300 - 308
Suppressor of cytokine signaling (SOCS) 2, a negative regulator of growth hormone (GH) and insulin-like growth factor 1 (IGF-1), which is associated with... 
SOCS2 | Cell growth | cell-penetrating protein | protein therapy | Cell-penetrating protein | Protein therapy | METASTASIS | GROWTH-HORMONE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | ANDROGEN | CHEMISTRY, APPLIED | PROGRESSION
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 804 - 15
Repeated cell divisions and aging impair stem cell function. However, the mechanisms by which this occurs are not fully understood. Here we show that... 
IN-VITRO | DNA-DAMAGE CHECKPOINT | COLOCALIZATION | MULTIDISCIPLINARY SCIENCES | DYSKERATOSIS-CONGENITA | EXPANSION | QUIESCENCE | END-PROTECTION | SELF-RENEWAL | SHELTERIN | EX-VIVO | Binding | Cell culture | Reactive oxygen species | Oxygen | DNA damage | Aging (artificial) | Stem cell transplantation | Proteins | Telomeres | Allografts | Stem cells | Aging | Damage | Telomerase | Deoxyribonucleic acid--DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2016, Volume 11, Issue 5, p. e0155558
Geminin regulates chromatin remodeling and DNA replication licensing which play an important role in regulating cellular proliferation and differentiation.... 
TRANSCRIPTION FACTORS | INHIBITION | STRUCTURAL BASIS | POLYCOMB-GROUP GENES | MULTIDISCIPLINARY SCIENCES | HEMATOPOIETIC STEM-CELLS | IN-VIVO | REGULATOR GEMININ | PLURIPOTENT CELLS | E3 UBIQUITIN LIGASE | DNA-REPLICATION | NIH 3T3 Cells | Humans | DNA-Binding Proteins - metabolism | Transfection | Transcription, Genetic | Real-Time Polymerase Chain Reaction | Fibroblast Growth Factor 4 - metabolism | Chromatin - chemistry | Fibroblasts - metabolism | Recombinant Proteins - metabolism | Geminin - metabolism | Mice, Inbred C57BL | Cell Cycle Proteins - metabolism | Gene Expression Regulation | Ubiquitin - chemistry | Chromatin Assembly and Disassembly | Proteasome Endopeptidase Complex - chemistry | DNA Replication | Nuclear Proteins - metabolism | Plasmids - metabolism | Amino Acid Motifs | Transcription Factors - metabolism | DNA Helicases - metabolism | Animals | Cell Cycle | K562 Cells | RAW 264.7 Cells | Mice | Physiological aspects | Chromatin | Genetic aspects | Research | DNA binding proteins | Cell cycle | Ubiquitin | BRG1 protein | Transcription | DNA polymerase | Science | Stem cell transplantation | Licenses | Biology | Remodeling | Nuclei | Proteins | E2F protein | Fibroblasts | Nuclease | Configurations | Geminin | Deoxyribonucleic acid--DNA | Recombinant | Embryo fibroblasts | Fibroblast growth factor 4 | Chromatin remodeling | DNA biosynthesis | Medicine | Stem cells | Proteasomes | Protein expression | Cancer | Deoxyribonucleic acid | DNA
Journal Article
Science, ISSN 0036-8075, 2/1999, Volume 283, Issue 5406, pp. 1317 - 1321
Journal Article
Journal Article
Science, ISSN 0036-8075, 12/1995, Volume 270, Issue 5241, pp. 1491 - 1494
The phosphorylation of the human estrogen receptor (ER) serine residue at position 118 is required for full activity of the ER activation function 1 (AF-1).... 
COS cells | Phosphorylation | Receptors | Cell growth | Reporter genes | Estrogen receptors | Reports | Breast cancer | Promoter regions | Genetic mutation | Transactivation | DEPENDENT TRANSCRIPTIONAL ACTIVATION | ONCOGENE | ELEMENT | HUMAN-BREAST-CANCER | TAMOXIFEN | MULTIDISCIPLINARY SCIENCES | GROWTH | 4-HYDROXYTAMOXIFEN | IDENTIFICATION | DOMAINS | BINDING | Protein Kinases - metabolism | Estradiol - analogs & derivatives | Receptors, Estrogen - metabolism | Humans | Transcriptional Activation - drug effects | Molecular Sequence Data | Estrogen Antagonists - pharmacology | Recombinant Fusion Proteins - metabolism | Polyunsaturated Alkamides | Somatomedins - pharmacology | Mitogen-Activated Protein Kinase Kinases | Transfection | Estradiol - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins p21(ras) - metabolism | Proto-Oncogene Proteins - metabolism | Amino Acid Sequence | Cell Line | Proto-Oncogene Proteins c-raf | Receptors, Estrogen - genetics | Serine - metabolism | Animals | Receptors, Estrogen - chemistry | Tamoxifen - pharmacology | Tamoxifen - analogs & derivatives | Enzyme Activation | Epidermal Growth Factor - pharmacology | Mutation | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Physiological aspects | Growth factors | Estrogen | Proteins | Cellular biology
Journal Article
FEBS Letters, ISSN 0014-5793, 2005, Volume 579, Issue 30, pp. 6821 - 6826
Recent studies have shown that adiponectin, an adipocyte-derived cytokine, acts as a potent inhibitor of inflammatory responses. It has been also demonstrated... 
Nuclear factor-κB | Inhibitor κB phosphorylation | Adiponectin receptor | Toll-like receptor | Adiponectin | Murine macrophage-like cell | glutathione | NF-κB-inducing kinase | LPS | reverse transcriptase-PCR | deoxycytidylate-phosphate-deoxyguanylate | IκB | NF-κB | tumor necrosis factor alpha | FBS | RT-PCR | ODN | CpG | TLR | globular adiponectin | oligodeoxynucleotide | GST | gAd | transferase | nuclear factor-κB | fetal bovine serum | NIK | inhibitor κB | TNF-α | LTA | lipoteichoic acid | ACRP30 | lipopolysaccharide | a 30-kDa adipocyte complement-related protein | PATHWAYS | adiponectin | inhibitor kappa B phosphorylation | RISK-FACTORS | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | nuclear factor-kappa B | BYPASS GRAFT-SURGERY | murine macrophage-like cell | CELL BIOLOGY | ACTINOBACILLUS-ACTINOMYCETEMCOMITANS | BIOPHYSICS | ADIPOSE-SPECIFIC PROTEIN | INSULIN-RESISTANCE | adiponectin receptor | ADAPTER PROTEIN | BACTERIAL-DNA | MYD88 | Luciferases - metabolism | Toll-Like Receptor 2 - antagonists & inhibitors | NF-kappa B - metabolism | Adipocytes - drug effects | Recombinant Fusion Proteins - metabolism | Dose-Response Relationship, Drug | Receptors, Adiponectin | I-kappa B Kinase - metabolism | Adiponectin - genetics | Adiponectin - metabolism | Phosphorylation - drug effects | Protein Synthesis Inhibitors - pharmacology | Toll-Like Receptor 4 - antagonists & inhibitors | Genes, Reporter | Cell Line | Adiponectin - pharmacology | Biotinylation | Toll-Like Receptor 9 - antagonists & inhibitors | Glutathione Transferase - metabolism | Receptors, Cell Surface - metabolism | Adiponectin - analysis | Toll-Like Receptor 2 - metabolism | 3T3-L1 Cells | Toll-Like Receptor 4 - metabolism | Cycloheximide - pharmacology | Animals | Signal Transduction - drug effects | Macrophages - drug effects | Mice | Toll-Like Receptor 9 - metabolism | Receptors, Cell Surface - genetics | Cell research | Glutathione transferase | Universities and colleges | Peptide hormones | Mitogens | Organic acids | Glutathione
Journal Article
Journal of Biochemistry, ISSN 0021-924X, 12/2011, Volume 150, Issue 6, pp. 635 - 648
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 09/2015, Volume 66, pp. 112 - 120
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 09/2015, Volume 66, p. 112
* PI polyamide targeting human TGF-[beta]1 gene promoter region regulates the EMT/MET process in MCF10A cells. * PI polyamide significantly increased... 
Hypertension | Bone morphogenetic proteins | Thiophene | Transforming growth factors | Polyamides | Medical colleges | Phosphatases | Genetic vectors | RNA | Stem cells
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2008, Volume 283, Issue 46, pp. 31575 - 31583
Recent studies using SOCS family knock-out mice have suggested that SOCS proteins have multiple biological functions in addition to their role as negative... 
SUPPRESSOR | HEPATOCELLULAR-CARCINOMA | COMPLEX | HYPERMETHYLATION | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY<