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1. Full Text ESTUDIO Y EDICION DE JOAQUIN ZULETA CARRANDI BIBLIOTECA INDIANA UNIVERSIDAD DE NAVARRA-IBEROAMERICANA
by Mateo B Martinic
Magallania, ISSN 0718-0209, 01/2016, Volume 44, Issue 1, p. 301
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2. Full Text Joaquin Ferrer Arellano, El sacerdocio, don y misterio. Teologia y espiritualidad del sacerdocio ministerial
by Mateo-Seco, Lucas F
Scripta Theologica, ISSN 0036-9764, 09/2011, Volume 43, Issue 3, p. 794
Autores | Obras | Aspectos religiosos | Sacerdocio | Teologia | Historia | Analisis
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3. Full Text Metals and metalloids in blood and feathers of common moorhens (Gallinula chloropus) from wetlands that receive treated wastewater
by López-Perea, Jhon J and Laguna, Celia and Jiménez-Moreno, María and Rodríguez Martín-Doimeadios, Rosa C and Feliu, Jordi and Mateo, Rafael
Science of the Total Environment, ISSN 0048-9697, 01/2019, Volume 646, pp. 84 - 92
We addressed the hypothesis that birds in eutrophic wetlands receiving wastewater treatment plant (WWTP) effluents are exposed to high levels of metals and... 
Ecological trap | Waterbirds | Wastewater | Metals | Body condition | HEAVY-METALS | METALLOTHIONEIN CONCENTRATIONS | MEDITERRANEAN WETLANDS | ENVIRONMENTAL SCIENCES | SAN-JOAQUIN VALLEY | BOTULISM OUTBREAKS | TRACE-ELEMENTS | TREATMENT PLANTS | SOUTHWESTERN SPAIN | DAIMIEL NATIONAL-PARK | SULFATE-REDUCING BACTERIA | Environmental Monitoring | Feathers - chemistry | Metals - analysis | Metals, Heavy | Waste Disposal, Fluid | Waste Water | Metals - blood | Spain | Wetlands | Metals - metabolism | Animals | Metalloids - blood | Metalloids - analysis | Metalloids - metabolism | Sewage | Purification | Ecosystems | Birds | Sediments (Geology) | Index Medicus
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4. Full Text Abstract IA18: Sensitivity and resistance biomarkers to PARP inhibitors in Mcrpc
by Mateo, Joaquin
Cancer Research, ISSN 0008-5472, 08/2018, Volume 78, Issue 16 Supplement, pp. IA18 - IA18
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5. Full Text Sequencing of agents in castration-resistant prostate cancer
by Lorente, David, MD and Mateo, Joaquin, MD and Perez-Lopez, Raquel, MD and de Bono, Johann S, Prof and Attard, Gerhardt, Dr
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 6, pp. e279 - e292
Summary Until 2010, docetaxel was the only agent with proven survival benefit for castration-resistant prostate cancer. The development of cabazitaxel,... 
Hematology, Oncology and Palliative Medicine | ANDROGEN RECEPTOR | MITOXANTRONE PLUS PREDNISONE | CIRCULATING TUMOR-CELLS | ONCOLOGY | SURVIVAL ANALYSIS | PHASE-III | DOUBLE-BLIND | ABIRATERONE ACETATE | QUALITY-OF-LIFE | ANTITUMOR-ACTIVITY | SIPULEUCEL-T | Radioisotopes - therapeutic use | Phenylthiohydantoin - therapeutic use | Humans | Docetaxel | Androstenes - therapeutic use | Male | Treatment Outcome | Tissue Extracts - therapeutic use | Prostatic Neoplasms, Castration-Resistant - drug therapy | Radium - therapeutic use | Abiraterone Acetate | Phenylthiohydantoin - analogs & derivatives | Prostatic Neoplasms, Castration-Resistant - pathology | Taxoids - therapeutic use | Prostatic Neoplasms, Castration-Resistant - epidemiology | Prostate cancer
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6. Full Text Stroke Prophylaxis in Atrial Fibrillation: Searching for Management Improvement Opportunities in the Emergency Department: The HERMES-AF Study
by Coll-Vinent, Blanca, MD, PhD and Martín, Alfonso, MD, PhD and Malagón, Francisco, MD and Suero, Coral, MD and Sánchez, Juan, MD, PhD and Varona, Mercedes, MD and Cancio, Manuel, MD and Sánchez, Susana, MD, PhD and Montull, Eugeni, MD and del Arco, Carmen, MD, PhD and HERMES-AF Invest and HERMES-AF Investigators
Annals of Emergency Medicine, ISSN 0196-0644, 2014, Volume 65, Issue 1, pp. 1 - 12
Study objective We determine the prevalence of stroke prophylaxis prescription in emergency department (ED) patients with atrial fibrillation and the factors... 
Emergency | BENEFIT | TASK-FORCE | EMERGENCY MEDICINE | WARFARIN | ORAL ANTICOAGULANTS | GUIDELINES | PREVENTION | THROMBOPROPHYLAXIS | CLINICAL CLASSIFICATION SCHEMES | TRENDS | REGISTRY | Stroke - prevention & control | Age Factors | Cross-Sectional Studies | Risk Assessment | Humans | Risk Factors | Atrial Fibrillation - complications | Anticoagulants - therapeutic use | Male | Emergency Service, Hospital - statistics & numerical data | Practice Patterns, Physicians' - statistics & numerical data | Spain - epidemiology | Sex Factors | Female | Aged | Emergency service | Hospitals | Drug therapy | Atrial fibrillation | Analysis | Anticoagulants (Medicine)
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7. Full Text DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer
by Mateo, Joaquin and Carreira, Suzanne and Sandhu, Shahneen and Miranda, Susana and Mossop, Helen and Perez-Lopez, Raquel and Nava Rodrigues, Daniel and Robinson, Dan and Omlin, Aurelius and Tunariu, Nina and Boysen, Gunther and Porta, Nuria and Flohr, Penny and Gillman, Alexa and Figueiredo, Ines and Paulding, Claire and Seed, George and Jain, Suneil and Ralph, Christy and Protheroe, Andrew and Hussain, Syed and Jones, Robert and Elliott, Tony and McGovern, Ursula and Bianchini, Diletta and Goodall, Jane and Zafeiriou, Zafeiris and Williamson, Chris T and Ferraldeschi, Roberta and Riisnaes, Ruth and Ebbs, Bernardette and Fowler, Gemma and Roda, Desamparados and Yuan, Wei and Wu, Yi-Mi and Cao, Xuhong and Brough, Rachel and Pemberton, Helen and A’Hern, Roger and Swain, Amanda and Kunju, Lakshmi P and Eeles, Rosalind and Attard, Gerhardt and Lord, Christopher J and Ashworth, Alan and Rubin, Mark A and Knudsen, Karen E and Feng, Felix Y and Chinnaiyan, Arul M and Hall, Emma and de Bono, Johann S
The New England Journal of Medicine, ISSN 0028-4793, 10/2015, Volume 373, Issue 18, pp. 1697 - 1708
Fourteen of 16 patients with metastatic, castration-resistant prostate cancer and genetic defects in repair of DNA damage had a response to the PARP inhibitor... 
POLY(ADP-RIBOSE) POLYMERASE | MEDICINE, GENERAL & INTERNAL | BRCA MUTATION CARRIERS | SENSITIVITY | ATM | HOMOLOGOUS RECOMBINATION | OVARIAN-CANCER | IONIZING-RADIATION | PARP INHIBITORS | MAINTENANCE THERAPY | DAMAGE | Humans | Middle Aged | Drug Resistance, Neoplasm | Male | Antineoplastic Agents - therapeutic use | Fatigue - chemically induced | DNA Repair - genetics | Prostatic Neoplasms - genetics | Neoplasm Metastasis - drug therapy | Genes, BRCA2 | Adult | Genes, Tumor Suppressor | Prostatic Neoplasms - drug therapy | Enzyme Inhibitors - adverse effects | Prostatic Neoplasms - pathology | Anemia - chemically induced | Piperazines - therapeutic use | Enzyme Inhibitors - therapeutic use | Piperazines - adverse effects | Poly(ADP-ribose) Polymerase Inhibitors | Phthalazines - therapeutic use | Aged | Mutation | Ataxia Telangiectasia Mutated Proteins - genetics | Phthalazines - adverse effects | Diagnosis | DNA repair | Prostate cancer | Analysis | BRCA2 protein | Adenosine | Inhibitor drugs | Tablets | BRCA1 protein | Anemia | Prostate-specific antigen | Poly(ADP-ribose) polymerase | Fatigue | Metastasis | Gene expression | Patients | Metastases | Castration | Ribose | Solid tumors | Molecular biology | Prostate | DNA sequencing
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8. Full Text Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer
by Pritchard, Colin C and Mateo, Joaquin and Walsh, Michael F and Walsh, Tom and De Sarkar, Navonil and Abida, Wassim and Beltran, Himisha and Garofalo, Andrea and Gulati, Roman and Carreira, Suzanne and Eeles, Rosalind and Elemento, Olivier and Rubin, Mark A and Robinson, Dan and Lonigro, Robert and Hussain, Maha and Chinnaiyan, Arul and Vinson, Jake and Filipenko, Julie and Garraway, Levi and Taplin, Mary-Ellen and AlDubayan, Saud and Han, G. Celine and Beightol, Mallory and Morrissey, Colm and Nghiem, Belinda and Cheng, Heather H and Montgomery, Bruce and Casadei, Silvia and Berger, Michael and Zhang, Liying and Zehir, Ahmet and Vijai, Joseph and Scher, Howard I and Sawyers, Charles and Schultz, Nikolaus and Kantoff, Philip W and Solit, David and Robson, Mark and Van Allen, Eliezer M and Offit, Kenneth and de Bono, Johann and Nelson, Peter S
The New England Journal of Medicine, ISSN 0028-4793, 08/2016, Volume 375, Issue 5, pp. 443 - 453
Inherited mutations in DNA-repair genes were found in nearly 12% of men with metastatic prostate cancer, as compared with 2.7% in an unselected general... 
BREAST-CANCER | MEDICINE, GENERAL & INTERNAL | GENOMICS | VARIANTS | DISEASE | GUIDELINES | RISK | AGGRESSIVENESS | OVARIAN-CANCER | BRCA1 | ASSOCIATION | Genetic Predisposition to Disease | Age Factors | Humans | Middle Aged | Male | DNA Repair - genetics | Incidence | Neoplasm Metastasis - genetics | Prostatic Neoplasms - genetics | DNA Mutational Analysis | Aged, 80 and over | Germ-Line Mutation | Aged | Research | Gene mutations | DNA repair | Prostate cancer | Risk factors | BRCA2 protein | BRCA1 protein | Risk groups | Genes | Metastasis | Metastases | Men | Mutation | Diagnosis | Prostate | Age | DNA sequencing
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9. Full Text Towards a New Classification for Metastatic Prostate Cancer
by Mateo, Joaquin and Carles, Joan
European Urology, ISSN 0302-2838, 03/2019, Volume 75, Issue 3, pp. 383 - 384
UROLOGY & NEPHROLOGY
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10. Full Text Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor
by Barber, Louise J and Sandhu, Shahneen and Chen, Lina and Campbell, James and Kozarewa, Iwanka and Fenwick, Kerry and Assiotis, Ioannis and Rodrigues, Daniel Nava and Reis-Filho, Jorge S and Moreno, Victor and Mateo, Joaquin and Molife, L Rhoda and De Bono, Johann and Kaye, Stan and Lord, Christopher J and Ashworth, Alan
The Journal of Pathology, ISSN 0022-3417, 02/2013, Volume 229, Issue 3, pp. 422 - 429
PARP inhibitors (PARPi) for the treatment of BRCA1 or BRCA2 deficient tumours are currently the focus of seminal clinical trials exploiting the concept of... 
BRCA | cancer | drug resistance | secondary mutation | massively parallel sequencing | PARP inhibitor | POLY(ADP-RIBOSE) POLYMERASE | OVARIAN-CANCER | PATHOLOGY | TUMORS | MAINTENANCE | THERAPY | ONCOLOGY | CARCINOMAS | BREAST CANCERS | Breast Neoplasms, Male - genetics | Humans | Middle Aged | Ovarian Neoplasms - pathology | Drug Resistance, Neoplasm | Male | Combined Modality Therapy | Breast Neoplasms, Male - drug therapy | Adenocarcinoma - drug therapy | Piperazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors | Sequence Analysis, DNA | Adenocarcinoma - secondary | Ovarian Neoplasms - genetics | Phthalazines - pharmacology | DNA Mutational Analysis | Female | Adenocarcinoma - genetics | Antineoplastic Agents - pharmacology | Breast Neoplasms, Male - pathology | Gene Expression Regulation, Neoplastic - drug effects | Mutation | Ovarian Neoplasms - drug therapy | BRCA2 Protein - genetics | Genetic aspects | Nucleotide sequencing | Drug resistance | Tumors | DNA sequencing
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11. Full Text Appraising iniparib, the PARP inhibitor that never was - What must we learn?
by Mateo, Joaquin and Ong, Michael and Tan, David S. P and Gonzalez, Michael A and De Bono, Johann S
Nature Reviews Clinical Oncology, ISSN 1759-4774, 12/2013, Volume 10, Issue 12, pp. 688 - 696
Several drugs targeting poly(ADP-ribose) polymerase (PARP) enzymes are under development. Responses have been observed in patients with germline mutations in... 
POLY(ADP-RIBOSE) POLYMERASE | OLAPARIB | PHASE-II TRIAL | GEMCITABINE/CARBOPLATIN | 4-IODO-3-NITROBENZAMIDE | RADIOSENSITIZATION | ONCOLOGY | CLINICAL-TRIALS | TUMOR-CELLS | NEGATIVE BREAST-CANCER | BASAL | Benzamides - therapeutic use | Humans | Female | Antineoplastic Agents - therapeutic use | Clinical Trials as Topic | Breast Neoplasms - drug therapy | Poly(ADP-ribose) Polymerase Inhibitors | Research Design | Antimitotic agents | Transferases | Physiological aspects | Breast cancer | Research | Antineoplastic agents | Drug therapy | Health aspects
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12. Full Text Phenotypic diversity of circulating tumour cells in patients with metastatic castration‐resistant prostate cancer
by McDaniel, Andrew S and Ferraldeschi, Roberta and Krupa, Rachel and Landers, Mark and Graf, Ryon and Louw, Jessica and Jendrisak, Adam and Bales, Natalee and Marrinucci, Dena and Zafeiriou, Zafeiris and Flohr, Penelope and Sideris, Spyridon and Crespo, Mateus and Figueiredo, Ines and Mateo, Joaquin and de Bono, Johann S and Dittamore, Ryan and Tomlins, Scott A and Attard, Gerhardt
BJU International, ISSN 1464-4096, 11/2017, Volume 120, Issue 5B, pp. E30 - E44
Objectives To use a non‐biased assay for circulating tumour cells (CTCs) in patients with prostate cancer (PCa) in order to identify non‐traditional CTC... 
metastatic castration‐resistant prostate cancer | PTEN | circulating tumour cells | ERG | liquid biopsy | metastatic castration-resistant prostate cancer | UROLOGY & NEPHROLOGY | LETHAL | EXPRESSION | BLOOD | Prostate-Specific Antigen - genetics | PTEN Phosphohydrolase - genetics | Neoplastic Cells, Circulating - pathology | Prostatic Neoplasms, Castration-Resistant - blood | Humans | Middle Aged | In Situ Hybridization, Fluorescence | Male | Disease Progression | Prostate-Specific Antigen - blood | Prostatic Neoplasms, Castration-Resistant - genetics | Prostatic Neoplasms, Castration-Resistant - pathology | Biomarkers, Tumor - blood | Neoplasm Metastasis - genetics | Phenotype | Receptors, Androgen - genetics | Neoplasm Metastasis - pathology | Aged, 80 and over | Adult | Aged | PTEN Phosphohydrolase - blood | Prostate cancer | Care and treatment | Metastasis | Cytokeratin | CD45 antigen | Metastases | Castration | Fluorescence in situ hybridization | Cell size | Immunofluorescence | Prostate | PTEN protein | Apoptosis | Tumors | metastatic castration resistant prostate cancer | Circulating tumour cells
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13. Full Text Novel drugs targeting the androgen receptor pathway in prostate cancer
by Mateo, Joaquin and Smith, Alan and Ong, Michael and de Bono, Johann S
Cancer and Metastasis Reviews, ISSN 0167-7659, 9/2014, Volume 33, Issue 2, pp. 567 - 579
After decades of limited success in the treatment of castration-resistant prostate cancer (CRPC), five novel therapeutics were granted Food and Drug... 
Biomedicine | Abiraterone | Androgen receptor | Cancer Research | Oncology | CYP17 | Enzalutamide | Prostate cancer | Biomedicine general | CONTROLLED-TRIAL | STEROIDAL INHIBITORS | PHASE-II | ANTITUMOR-ACTIVITY | CASTRATION | HEAT-SHOCK-PROTEIN | THERAPY | ONCOLOGY | ABIRATERONE ACETATE | INCREASED SURVIVAL | CLINICAL ACTIVITY | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - pathology | Androgen Receptor Antagonists - therapeutic use | Antineoplastic Agents, Hormonal - pharmacology | Humans | Receptors, Androgen - metabolism | Male | Androgen Receptor Antagonists - pharmacology | Molecular Targeted Therapy | Drug Discovery | Signal Transduction - drug effects | Antineoplastic Agents, Hormonal - therapeutic use | Neoplasm Staging | Prostatic Neoplasms - drug therapy | Drugs | Cellular signal transduction | Drug approval | Cytochrome P-450
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