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Circulation Journal, ISSN 1346-9843, 2016
Journal Article
Circulation Journal, ISSN 1346-9843, 2016, Volume 80, Issue 4, pp. 825 - 826
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2019, Volume 381, Issue 12, pp. 1103 - 1113
Patients with atrial fibrillation and stable coronary artery disease were assigned to receive either rivaroxaban monotherapy or combination therapy with... 
MEDICINE, GENERAL & INTERNAL | ORAL ANTICOAGULANT | RIVAROXABAN | JAPANESE PATIENTS | ANTIPLATELET THERAPY | ARTERY-DISEASE | FOCUSED UPDATE | Rivaroxaban | Treatment outcome | Usage | Safety and security measures | Atrial fibrillation | Analysis | Thrombolytic drugs | Drug therapy
Journal Article
Circulation Journal, ISSN 1346-9843, 2019, Volume 83, Issue 2, pp. 283 - 284
Journal Article
Circulation Journal, ISSN 1346-9843, 2018
Journal Article
International Heart Journal, ISSN 1349-2365, 2014, Volume 55, Issue 4, pp. 281 - 286
Administration of drugs and other therapeutic agents has been the central strategy of contemporary medicine for cardiovascular disease. The use of a drug... 
Myocardial infarction | Inflammation | Ischemia reperfusion | Nanotechnology | Atherosclerosis | MYOCARDIUM | CARDIAC & CARDIOVASCULAR SYSTEMS | NEUTROPHIL | PITAVASTATIN | PERMEABILITY | MACROPHAGES | NANOMEDICINE | THERAPEUTIC NEOVASCULARIZATION | ISCHEMIA-REPERFUSION INJURY | ELUTING STENTS | LIPOSOMES
Journal Article
Circulation, ISSN 0009-7322, 11/2015, Volume 132, Issue Suppl_3 Suppl 3, pp. A18536 - A18536
IntroductionMitochondrial injury and inflammation play temporally and spatially different roles in myocardial ischemia-reperfusion (IR) injury, which demand... 
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0132451
Aim There is an unmet need to develop an innovative cardioprotective modality for acute myocardial infarction (AMI), for which the effectiveness of... 
GLYCOGEN-SYNTHASE KINASE-3-BETA | MITOCHONDRIAL PERMEABILITY TRANSITION | INDUCED CARDIOMYOCYTE APOPTOSIS | OXIDATIVE STRESS | WORKING GROUP | MULTIDISCIPLINARY SCIENCES | CELLULAR BIOLOGY | MONOCYTES | MICE | EUROPEAN-SOCIETY | ISCHEMIA/REPERFUSION | Quinolines - blood | Capillary Permeability | Injections, Intravenous | Myocardium - chemistry | Cardiotonic Agents - analysis | Male | Quinolines - administration & dosage | Cardiotonic Agents - therapeutic use | Flow Cytometry | Nanoparticles - therapeutic use | Disease Models, Animal | Echocardiography | Rats | Myocardium - pathology | Proto-Oncogene Proteins c-akt - physiology | Rats, Sprague-Dawley | Blotting, Western | Quinolines - analysis | Animals | Cardiotonic Agents - administration & dosage | Myocardial Infarction - drug therapy | Signal Transduction - drug effects | Cardiotonic Agents - blood | Phosphatidylinositol 3-Kinases - physiology | Quinolines - therapeutic use | Drug Delivery Systems - methods | Myocardial Reperfusion Injury - prevention & control | Ischemia | Models | Inflammation | Permeability | Health aspects | Statins | Heart attack | Myocardial infarction | Heart | Therapy | Phosphorylation | Intravenous administration | Heart attacks | Mitochondrial permeability transition pore | Cyclosporins | Membrane permeability | AKT protein | Myocardial ischemia | Cardiovascular disease | Activation | Leukocytes | Kinases | Polylactide-co-glycolide | Nanoparticles | Reperfusion | Rodents | Glycolic acid | Peripheral blood | Inhibition | Pretreatment | University graduates | Hypertension | CD11b antigen | Polylactic acid | Cardiomyocytes | 1-Phosphatidylinositol 3-kinase | Medicine | White blood cells | Ostomy | Injury prevention | Inhibitors | Acids | Medical prognosis | Wortmannin | Myocardium | Infarction | Ventricle | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2016, Volume 11, Issue 9, p. e0162425
Background There is an unmet need to develop an innovative cardioprotective modality for acute myocardial infarction, for which interventional reperfusion... 
MULTIDISCIPLINARY SCIENCES | Blood Pressure | Myocardial Infarction - blood | Quinolines - blood | Phosphorylation | Nanoparticles - chemistry | Polylactic Acid-Polyglycolic Acid Copolymer | Myocardial Reperfusion Injury - complications | Quinolines - administration & dosage | Kidney Function Tests | Cardiotonic Agents - therapeutic use | Quinolines - pharmacokinetics | Ventricular Remodeling | Swine | Cell Death | Swine, Miniature | Anesthesia | Myocardial Infarction - physiopathology | Myocardial Reperfusion Injury - drug therapy | Proto-Oncogene Proteins c-akt - metabolism | Myocardial Reperfusion Injury - blood | Disease Models, Animal | Liver Function Tests | Heart Rate | Lactic Acid - chemistry | Consciousness | No-Reflow Phenomenon | Translational Medical Research | Cells, Cultured | Myocardium - pathology | Myocardial Reperfusion Injury - physiopathology | Stroke Volume | Magnetic Resonance Imaging | Myocardial Infarction - complications | Myocytes, Cardiac - pathology | Animals | Cardiotonic Agents - administration & dosage | Myocardial Infarction - drug therapy | Myocardial Reperfusion | Polyglycolic Acid - chemistry | Quinolines - therapeutic use | Heart beat | Ischemia | Electrocardiogram | Electrocardiography | Health aspects | Heart attack | Myocardial infarction | Animal models | Intravenous administration | Pressure effects | Heart attacks | AKT protein | Cardiovascular disease | Experiments | Blood | Polylactide-co-glycolide | Nanoparticles | Reperfusion | Transmitters | Rodents | Glycolic acid | Blood pressure | Polyvinyl alcohol | Heart diseases | University graduates | EKG | Pigs | Medical research | Polylactic acid | Coronary artery | Cardiomyocytes | Pharmacology | Telemetry | Metabolism | 1-Phosphatidylinositol 3-kinase | Medicine | Heart rate | Studies | Hogs | Side effects | Ostomy | Injury prevention | Acids | Magnetic resonance imaging | Myocardium | Infarction | Ventricle | Laboratory animals | Apoptosis
Journal Article
Journal of Atherosclerosis and Thrombosis, ISSN 1340-3478, 2016, Volume 23, Issue 7, pp. 757 - 765
Journal Article
Scientific Reports, ISSN 2045-2322, 02/2016, Volume 6, Issue 1, p. 20467
Myocardial ischemia-reperfusion (IR) injury limits the therapeutic effects of early reperfusion therapy for acute myocardial infarction (MI), in which... 
LOCAL-DELIVERY | INFLAMMATORY MONOCYTES | HYPERTROPHY | MYOCARDIAL-INFARCTION | PITAVASTATIN | NUCLEAR-FACTOR | MULTIDISCIPLINARY SCIENCES | CARDIAC MYOCYTES | THERAPEUTIC NEOVASCULARIZATION | NEOINTIMA FORMATION | CELL-DEATH | Mitochondria, Heart - metabolism | Nanoparticles - chemistry | Cyclosporine - pharmacology | Male | Mitochondria, Heart - drug effects | Drug Carriers - chemistry | Cardiotonic Agents - therapeutic use | Myocardial Reperfusion Injury - pathology | Myocardial Reperfusion Injury - drug therapy | Disease Models, Animal | Hydrogen Peroxide - toxicity | Mitochondrial Membrane Transport Proteins - metabolism | Lactic Acid - chemistry | Myocytes, Cardiac - cytology | Cytochromes c - metabolism | Mice, Inbred C57BL | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Rats | Mitochondrial Membrane Transport Proteins - drug effects | Cardiotonic Agents - chemistry | Cardiotonic Agents - pharmacology | Rats, Sprague-Dawley | Cyclosporine - therapeutic use | Myocardial Reperfusion Injury - metabolism | Animals | Myocytes, Cardiac - drug effects | Cyclosporine - chemistry | Polyglycolic Acid - chemistry | Myocytes, Cardiac - metabolism | Mice | Oxidative Stress - drug effects | Ventricular Remodeling - drug effects | Heart | Myocardial infarction | Oxidative stress | Hydrogen peroxide | Mitochondrial permeability transition pore | Cyclosporins | Membrane permeability | Myocardial ischemia | Cardiomyocytes | Mitochondrial DNA | Inflammation | Permeability | Polylactide-co-glycolide | Nanoparticles | Monocytes | Reperfusion | Ischemia | Rodents | Glycolic acid | Myocardium | MPTP | Ventricle
Journal Article
Scientific Reports, ISSN 2045-2322, 07/2016, Volume 6, Issue 1, p. 29601
Myocardial ischemia-reperfusion (IR) injury limits the therapeutic effect of early reperfusion therapy for acute myocardial infarction (AMI), in which the... 
INFARCT SIZE | PERCUTANEOUS CORONARY INTERVENTION | II TYPE-1 RECEPTOR | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | PPAR-GAMMA | THERAPEUTIC NEOVASCULARIZATION | NEUTROPHIL DEPLETION | DEFICIENT MICE | PRIMARY PCI | SPLENIC RESERVOIR
Journal Article