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index medicus (178) 178
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matrix metalloproteinase (16) 16
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abridged index medicus (14) 14
gene expression (14) 14
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matrix metalloproteinase 7 - genetics (14) 14
medicine, research & experimental (14) 14
mice, knockout (14) 14
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matrix metalloproteinase 9 - metabolism (13) 13
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matrix metalloproteinases - metabolism (9) 9
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SCIENCE, ISSN 0036-8075, 03/2002, Volume 295, Issue 5564, pp. 2387 - 2392
For at least 30 years, matrix metalloproteinases (MMPs) have been heralded as promising targets for cancer therapy on the basis of their massive up-regulation... 
BREAST-CANCER | CARCINOGENESIS | METASTASIS | B16-F10 MELANOMA-CELLS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | TISSUE INHIBITOR | INTESTINAL TUMORIGENESIS | MICE | EXPRESSION | MARIMASTAT
Journal Article
NATURE REVIEWS CANCER, ISSN 1474-175X, 10/2007, Volume 7, Issue 10, pp. 800 - 808
Proteases have long been associated with cancer progression because of their ability to degrade extracellular matrices, which facilitates invasion and... 
CELL LUNG-CANCER | MATRIX METALLOPROTEINASES | PROMOTER HYPERMETHYLATION | ONCOLOGY | HUMAN MACROPHAGE METALLOELASTASE | PROSTATE-SPECIFIC ANTIGEN | GENE-EXPRESSION | SERINE-PROTEASE | HUMAN BREAST-CANCER | NF-KAPPA-B | DIPEPTIDYL PEPTIDASE-IV
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2006, Volume 103, Issue 5, pp. 1492 - 1497
G protein-coupled receptor ligand-dependent transactivation of growth factor receptors has been implicated in human cancer cell proliferation, migration, and... 
Receptors | Phosphorylation | Prostaglandins | Liver | Antibodies | Metastasis | Colorectal neoplasms | Transactivation | Cytosol | Tumors | EGF receptor | c-Src | Prostaglandin E | Prostaglandin E receptor | ACTIVATION | prostaglandin E receptor | CELL MOTILITY | MECHANISM | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | EP4 | prostaglandin E-2 | COLON-CANCER | BREAST-CANCER | GROWTH-FACTOR RECEPTOR | metastasis | EXPRESSION | CARCINOMA | Immunohistochemistry | Immunoprecipitation | src-Family Kinases | Protein-Tyrosine Kinases - metabolism | Humans | Transcriptional Activation | Arrestins - physiology | Collagen - chemistry | Arrestins - metabolism | Proteoglycans - chemistry | Receptors, Prostaglandin E, EP4 Subtype | Neoplasm Metastasis | Receptor, Epidermal Growth Factor - metabolism | Time Factors | Cell Membrane - metabolism | Densitometry | Signal Transduction | Phosphotyrosine - chemistry | Blotting, Western | Disease Progression | Dinoprostone - metabolism | Models, Biological | beta-Arrestin 1 | beta-Arrestins | Cell Line, Tumor | Cytosol - metabolism | Laminin - chemistry | Colorectal Neoplasms - pathology | Drug Combinations | Microscopy, Fluorescence | Receptors, Prostaglandin E - metabolism | Cell Movement | Proteins | Medical research | Signal transduction | Colorectal cancer | Cell adhesion & migration | Index Medicus | Biological Sciences | prostaglandin E2
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 09/2013, Volume 31, Issue 27, pp. 3432 - 3438
Purpose Pancreatic cancer clinical trials open in the United States and their accrual were examined to identify opportunities to accelerate progress in the... 
SURVIVAL | NATION | ONCOLOGY | GEMCITABINE | United States - epidemiology | Pancreatic Neoplasms - epidemiology | Clinical Trials as Topic - statistics & numerical data | Humans | Female | Male | Research Design | Pancreatic Neoplasms - therapy | Index Medicus
Journal Article
Journal Article
CANCER RESEARCH, ISSN 0008-5472, 07/2014, Volume 74, Issue 14, pp. 4006 - 4006
Journal Article
Cancer Cell, ISSN 1535-6108, 2005, Volume 7, Issue 5, pp. 485 - 496
We developed a rodent model that mimics the osteoblastic and osteolytic changes associated with human metastatic prostate cancer. Microarray analysis... 
ONCOLOGY | MATRIX-METALLOPROTEINASE INHIBITORS | BONE METASTASES | IN-VIVO | GROWTH | TUMOR | MICE | OSTEOPROTEGERIN | MODEL | EXPRESSION | T-ANTIGEN | Prostatic Neoplasms - metabolism | Receptor Activator of Nuclear Factor-kappa B | Membrane Glycoproteins - metabolism | Gene Expression - genetics | Humans | Rats, Inbred F344 | Actins - metabolism | Tartrate-Resistant Acid Phosphatase | Male | Monocytes - metabolism | Osteolysis - etiology | RANK Ligand | Gene Expression Profiling | Osteoprotegerin | Acid Phosphatase - metabolism | Matrix Metalloproteinase 7 - metabolism | Isoenzymes - metabolism | Skull - pathology | Carrier Proteins - pharmacology | Osteolysis - pathology | Disease Models, Animal | Receptors, Tumor Necrosis Factor - genetics | Glycoproteins - genetics | Osteoclasts - pathology | Membrane Glycoproteins - pharmacology | Mice, Inbred C57BL | Parathyroid Hormone-Related Protein - genetics | Rats | Up-Regulation - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Osteoclasts - metabolism | Osteolysis - metabolism | Down-Regulation - genetics | Membrane Glycoproteins - genetics | Mice, Knockout | Monocytes - drug effects | Carrier Proteins - genetics | Matrix Metalloproteinase 7 - genetics | Animals | Carrier Proteins - metabolism | Models, Biological | Mice | Prostatic Neoplasms - complications | Prostate cancer | Analysis | Metastasis | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, pp. e22775 - e22775
Journal Article