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Journal Article
Journal Article
Journal of Gastroenterology, ISSN 0944-1174, 7/2017, Volume 52, Issue 7, pp. 800 - 808
Journal Article
Cancer Science, ISSN 1347-9032, 07/2016, Volume 107, Issue 7, pp. 1029 - 1038
The major mechanism of imatinib (IM) resistance of CML is the reactivation of ABL kinase either through BCR‐ABL gene amplification or mutation. We investigated... 
Chronic myelogenous leukemia | combination therapy | ponatinib | imatinib‐resistant | panobinostat | Panobinostat | Combination therapy | Imatinib-resistant | Ponatinib | imatinib-resistant | TARGETED THERAPY | BCR-ABL | CHAPERONE FUNCTION | CHRONIC MYELOID-LEUKEMIA | ONCOLOGY | PHILADELPHIA-CHROMOSOME | CHROMOSOME-POSITIVE LEUKEMIAS | TYROSINE KINASE INHIBITOR | 3-YEAR FOLLOW-UP | HISTONE DEACETYLASE INHIBITORS | Imatinib Mesylate - pharmacology | Humans | Histone Deacetylases - metabolism | Imidazoles - pharmacology | Pyridazines - pharmacology | HSP70 Heat-Shock Proteins - metabolism | Drug Synergism | Acetylation - drug effects | Fusion Proteins, bcr-abl - genetics | Signal Transduction - drug effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Cell Line, Tumor | Indoles - pharmacology | Histones - metabolism | Phosphorylation - drug effects | Hydroxamic Acids - pharmacology | Fusion Proteins, bcr-abl - metabolism | Drug Resistance, Neoplasm - drug effects | Antimitotic agents | Heat shock proteins | Antineoplastic agents | Protein kinases | Analysis | Leukemia | BCR protein | Histone deacetylase | Hsp90 protein | Phosphorylation | Transcription | Cytotoxicity | AKT protein | Kinases | Drug resistance | Proteins | Acetylation | Drug dosages | Protein-tyrosine kinase | Tyrosine | Imatinib | Extracellular signal-regulated kinase | Abl protein | Hsp70 protein | Gene expression | Gene amplification | Cell lines | Lymphomas | Mutation | Alzheimers disease | Binding sites | Histone H3 | Cancer | Apoptosis | Original
Journal Article
Journal Article
BMC Medicine, ISSN 1741-7015, 05/2012, Volume 10, Issue 1, pp. 45 - 45
Journal Article
British Journal of Haematology, ISSN 0007-1048, 10/2017, Volume 179, Issue 2, pp. 246 - 255
Journal Article
PLOS ONE, ISSN 1932-6203, 10/2018, Volume 13, Issue 10, p. e0204039
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e69891
Journal Article