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Annals of Oncology, ISSN 0923-7534, 11/2015, Volume 26, Issue suppl 7, pp. vii30.3 - vii30
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 09/2011, Volume 31, Issue 18, pp. 3802 - 3819
Journal Article
PLoS Pathogens, ISSN 1553-7366, 08/2013, Volume 9, Issue 8, p. e1003533
The innate immune system is essential for controlling viral infections, but several viruses have evolved strategies to escape innate immunity. RIG-I is a... 
VIRAL-RNA | RECOGNITION | HEPATITIS-C-VIRUS | MICROBIOLOGY | KAPPA-B | SIGNALING PROTEIN | VIROLOGY | STRUCTURAL BASIS | PATHWAY | ADAPTER PROTEIN | HELICASE | PARASITOLOGY | E3 UBIQUITIN LIGASE | Hepatitis C - metabolism | Hepacivirus - immunology | Humans | Cercopithecus aethiops | Hepacivirus - genetics | Mutation, Missense | Hepacivirus - metabolism | Tripartite Motif Proteins | DNA-Binding Proteins - metabolism | Hepatitis C - immunology | Ubiquitin-Protein Ligases - immunology | HEK293 Cells | Ubiquitination - physiology | DEAD-box RNA Helicases - metabolism | Transcription Factors - immunology | Vero Cells | Carrier Proteins - immunology | Viral Nonstructural Proteins - immunology | Protein Structure, Tertiary | DEAD Box Protein 58 | DNA-Binding Proteins - immunology | Ubiquitin-Protein Ligases - metabolism | Viral Nonstructural Proteins - genetics | Hepatitis C - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Immunity, Innate | Hep G2 Cells | Mice, Knockout | Transcription Factors - metabolism | Carrier Proteins - genetics | DEAD-box RNA Helicases - genetics | Animals | Carrier Proteins - metabolism | DEAD-box RNA Helicases - immunology | Viral Nonstructural Proteins - metabolism | Mice | Ubiquitin-Protein Ligases - genetics | Amino Acid Substitution | Antiviral agents | Immune response | Drug interactions | Physiological aspects | Dosage and administration | Research | Ubiquitin-proteasome system | Health aspects | Hepatitis | Infections | Kinases | Viral infections | Immune system
Journal Article
2015, ISBN 9784431553274
This book overviews cancer immunity from broad scientific fields, based on the concept that cancer is a sort of by-product of infection, inflammation, and host... 
Medicine | Immunology | Oncology
Web Resource
Cancer Science, ISSN 1347-9032, 12/2015, Volume 106, Issue 12, pp. 1659 - 1668
Immune‐enhancing adjuvants usually targets antigen (Ag)‐presenting cells to tune up cellular and humoral immunity. CD 141 + dendritic cells ( DC ) represent... 
PolyI:C | Toll‐like receptor 2/3 | Antigen‐presenting dendritic cell (CD8α | DC, CD141 | BCG | 1 pathway | TICAM | CWS | DC | TICAM-1 pathway | BCG-CWS | Antigen-presenting dendritic cell (CD8α | Toll-like receptor 2/3 | Cell competition | NATURAL-KILLER-CELLS | DOUBLE-STRANDED-RNA | BACILLUS-CALMETTE-GUERIN | cell death | LUNG-CANCER | CELL-WALL SKELETON | cellular senescence | tumor progression | ONCOLOGY | SUPPRESSOR-CELLS | cellular cooperation | PATTERN-RECOGNITION RECEPTORS | T-CELLS | CD8-ALPHA(+) DENDRITIC CELLS | CROSS-PRESENTATION | Cancer Vaccines - immunology | Immunotherapy - methods | Adjuvants, Immunologic - pharmacology | Animals | Toll-Like Receptor 2 - agonists | Humans | Toll-Like Receptor 3 - agonists | Antigens | Care and treatment | Dendritic cells | Analysis | Immunotherapy | Vaccines | Drug therapy | T cells | Cancer | CD8 antigen | Bladder | Lymphocytes T | Kinases | Cancer vaccines | Proteins | Hepatitis | Toll-like receptors | Bacteria | Immunity (humoral) | Natural killer cells | Immune system | Pathogens | Medical research | Cell survival | TLR7 protein | Cytokines | Peptidoglycans | Adjuvants | Inflammation | Pattern recognition | TLR3 protein | TLR9 protein | CD4 antigen | Lipoproteins | TLR1 protein | Major histocompatibility complex | TLR2 protein | Agonists | Chemokines | Apoptosis | Review | Antigen‐presenting dendritic cell (CD8α+ DC, CD141+ DC) | BCG–CWS | Toll‐like receptor 2 | TICAM‐1 pathway
Journal Article
Advanced drug delivery reviews, ISSN 0169-409X, 07/2019
Vaccine immunotherapy consisting of tumor antigens combined with an immune-enhancing adjuvant fosters cytotoxic T cell (CTL) proliferation. Clinically, polyI:C... 
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 03/2017, Volume 24, Issue 3, pp. 385 - 396
PolyI:C, a synthetic double-stranded RNA analog, acts as an immune-enhancing adjuvant that regresses tumors in cytotoxic T lymphocyte (CTL)-dependent and... 
TOLL-LIKE RECEPTOR-3 | DENDRITIC CELLS | INFILTRATING NEUTROPHILS | MULTIPLE-SCLEROSIS | MICROENVIRONMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | PEROXYNITRITE-INDUCED APOPTOSIS | SUPPRESSOR-CELLS | CANCER | URIC-ACID | CELL BIOLOGY | Myeloid Cells - cytology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Adaptor Proteins, Vesicular Transport - deficiency | Adaptor Proteins, Vesicular Transport - genetics | Caspase 3 - metabolism | Caspase 8 - metabolism | Spleen - drug effects | Adaptor Proteins, Vesicular Transport - metabolism | T-Lymphocytes, Cytotoxic - drug effects | Antigens, Ly - metabolism | RNA, Double-Stranded - metabolism | Receptor, Interferon alpha-beta - genetics | T-Lymphocytes, Cytotoxic - immunology | Poly I-C - pharmacology | Reactive Nitrogen Species - metabolism | Receptor, Interferon alpha-beta - deficiency | Mice, Inbred C57BL | Cells, Cultured | Spleen - cytology | Mice, Knockout | Animals | Antigens, Ly - immunology | Signal Transduction - drug effects | Spleen - metabolism | Lymphocyte Activation - drug effects | Adaptor Proteins, Signal Transducing - deficiency | Adaptor Proteins, Signal Transducing - genetics | Myeloid Cells - metabolism | Cell Proliferation - drug effects | Mice | CD11b Antigen - metabolism | T-Lymphocytes, Cytotoxic - cytology | Original Paper
Journal Article
Nature, ISSN 0028-0836, 05/2016, Volume 534, Issue 7607, pp. 402 - 406
Journal Article